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12/11/2013 Frequency of Emergencies • Annually Medical Emergencies in the Dental Office Matthew E. Dudziak, DDS MD Christopher C. Choi, DDS MD • Every 1.2 minutes someone dies of a sudden cardiac arrest • Every 20 seconds someone has a heart attack • Every 45 seconds someone has a stroke • Every 3.3 minutes someone dies from a stroke • Every 3 minutes someone has a seizure for the first time • Every 6.6 minutes someone has an anaphylactic reaction Dental Economics July 2007 Roberson DMD and Rothman DDS Emergencies in Dental Office Type of Emergency Syncope Mild Allergic Reaction Angina Pectoris Postural Hypotension Seizures Total Number Percentage 15,407 2,583 2,552 2,475 1,595 51.6% 8.7% 8.6% 8.3% 5.3% JADA 112:499-501, 1986 JADA 124:40-53, 1993 Emergencies in Dental Office Type of Emergency Asthmatic Attack Hyperventilation Epinephrine Reaction Insulin Shock (Hypoglycemia) Cardiac Arrest Total Number Percentage 1,392 1,326 913 4.7% 4.4% 3.1% 890 3.0% 331 1.1% JADA 112:499-501, 1986 JADA 124:40-53, 1993 Emergencies in Dental Office Emergencies in Dental Office Type of Emergency Total Number Percentage Type of Emergency Total Number Percentage Anaphylactic Reaction Myocardial Infraction Local Anesthesia Overdose Acute Pulmonary Edema Diabetic Coma 304 289 1.0% 1.0% 204 0.7% Cerebrovascular Accident Adrenal Insufficiency Thyroid Storm 0.2% 0.1% 0.0% 141 109 0.5% 0.4% 68 25 4 30,608 JADA 112:499-501, 1986 JADA 124:40-53, 1993 JADA 112:499-501, 1986 JADA 124:40-53, 1993 1 12/11/2013 The Five Deadly Misconceptions 1. A medical emergency will not happen to me. 2. A medical emergency will not happen in the office. 3. Calling 911/EMS is the answer. 4. My staff and I won’t panic during a medical emergency. 5. CPR is all we need to know. Prevention • “Complete system of physical evaluation for all prospective dental patients would be capable of preventing approximately 90% of all lifethreatening emergencies.” • “When you prepare for an emergency, the emergency ceases to exist.” Dental Economics July 2007 Roberson DMD and Rothman DDS 5-Point Plan to Prevent Emergencies • Use careful, routine patient assessment procedures. • Document and update accurate, comprehensive patient records. • Implement stress reduction protocols. • Recognize early signs of emergency distress. • Organize team management plan for emergency preparedness. Vital Signs • • • • Temperature Pulse Blood Pressure Respiratory Rate Information Gathering • Ask open ended questions • Medical History • Medications including herbal medications • Surgical History • Social History • Allergies • Review organ systems (General, Neurological, Cardiovascular, Respiratory, Gastrointestinal, Renal, Musculoskeletal…) Temperature • Oral - 97.3 and 99.1 °F • Fever – 98.9 °F in a.m. and 99.9 °F in p.m. • Hyperthermia - > 104 °F 2 12/11/2013 Pulse • Normal – 60 to 100 bpm • Tachycardia - > 100 bpm • Bradycardia - < 60 bpm Respiratory Rate • • • • • • birth to 6 weeks: 30–60 breaths per minute 6 months: 25–40 breaths per minute 3 years: 20–30 breaths per minute 6 years: 18–25 breaths per minute 10 years: 15–20 breaths per minute adults: 12–24 breaths per minute Emergency Duties Four-Member Dental Team TEAM MEMBER 1: LEADER • Directs team members • Positions the patient and stays with him or her • Performs “ABCs”† of cardiopulmonary resuscitation (CPR) • Takes command and appears calm • States instructions directly and clearly • Requests acknowledgment from team members that instructions are understood • Fosters open exchange among team members • Concentrates on what is right for the patient, not who is right Blood Pressure Blood Pressure Category Normal Systolic mm Hg (upper #) Diastolic mm Hg (lower #) less than 120 and less than 80 Prehypertension 120 – 139 or 80 – 89 High Blood Pressure (Hypertension) Stage 1 140 – 159 or 90 – 99 High Blood Pressure (Hypertension) Stage 2 160 or higher or 100 or higher Hypertensive Crisis (Emergency care needed) Higher than 180 or Higher than 110 Team • Know your team • Know your roles • Practice, Practice, Practice Emergency Duties Four-Member Dental Team TEAM MEMBER 2 • Brings emergency kit • Brings oxygen tank and attaches appropriate delivery system • Brings automated external defibrillator • Assists with ABCs of CPR, including monitoring vital signs • Checks oxygen tank regularly • Checks emergency kit regularly • Prepares drugs for administration 3 12/11/2013 Emergency Duties Four-Member Dental Team TEAM MEMBER 3 • Telephones emergency medical services (9-1-1) • Meets paramedics at building entrance • Keeps chronological log of events • Assists with ABCs of CPR Basic Dental Office Emergencies • Neurologic o o o o Syncope Postural Hypotension Cerebrovascular Accident Seizure Disorder • Respiratory Distress o o o o Dyspnea Hyperventilation Syndrome Asthmatic Attack / Bronchospasm Airway Obstruction • Cardiovascular o Angina Pectoris o Acute Myocardial Infarction Emergency Duties Four-Member Dental Team TEAM MEMBER 4 • Assists with ABCs of CPR • Assists with other duties as needed JADA 2010;141(suppl 1):8S-13S Basic Dental Office Emergencies • Blood pressure abnormalities o Hypertension o Hypotension • Diabetes o Hyperglycemia o Hypoglycemia • Allergic Reactions o Urticaria / Pruritus o Anaphylactic shock o Epinephrine reaction o Drug Overdose o Local Anesthetics o Sedatives/Hypnotics o Narcotics Neurologic Emergencies • Syncope • Cerebrovascular Accident • Seizure Disorder Syncope 4 12/11/2013 What to do if someone is fainting What is syncope? • • • • Trendelenburg Establish airway 100% Oxygen Apply cold compress to pts forehead • Assess consciousness • Monitor vital signs • Sudden, brief loss of consciousness • Decreased blood flow to the brain • Pre-syncope a person may feel lightheaded Causes of syncope • • • • • • Vasovagal reaction Vasovagal reaction Panic or anxiety attacks Hyperventilation Low blood sugar Irregular heart beat Seizures • A reflex of the involuntary nervous system that causes – Decreased heart rate (bradycardia) – Vasodilation (hypotension) • Decreased cardiac output • Less blood flow to head Common Triggers • • • • • Sight of blood Having blood drawn Straining (bowel movement) Standing for extended periods Heat exposure Signs/symptoms/manifestations • • • • Pallor - loss of color Sensation of warmth Lightheadedness Diaphoresis (excessive sweating – cold and clammy) • Loss of consciousness • Dilation of pupils 5 12/11/2013 Basic Treatment • Place patient in trendelenburg (head down, feet up) • Assess consciousness • Assess Airway, Breathing, Circulation (abc’s) Treatment • • • • • • Advanced Syncope Loss of consciousness more then 5 minutes • Vital signs unstable • Re-consider diagnosis – Seizure – Heart Attack – Stroke – Hypoglycemia 100% oxygen Monitor vitals Crushed ammonia under nose Cold compresses to forehead or neck Reassure and relax pt Full recovery 20 minutes Prevention • • • • • • Thorough history Stress reduction Pre op sedation Patient monitoring 100% oxygen Early recognition • Activate EMS • Start ACLS Definition • Rapid fall in blood pressure when moving form supine to upright position • 20 mm Hg systolic BP • 10 mm Hg diastolic BP Postural (Orthostatic) Hypotension 6 12/11/2013 Causes • Blood pools in lower extremity when standing causing decreased cardiac output and subsequent hypotension, decreased blood flow to brain • Hypovolemia – Dehydration – Blood loss – Anemia Risk Factors • • • • • • • Treatment Symptoms/signs/manifestations • • • • Dizziness Blurred or dimmed vision Lightheadedness Fainting (extreme cases) Prolonged periods of reclining, positioning Late stage pregnancy Advanced age Venous defects in legs-Varicose veins Exhaustion Starvation Nitrous oxide • • • • • • • Return patient to supine of trendelenburg Maintain airway Administer oxygen may assist recover Monitor pulse Ammonia capsules Cold compresses Reposition patient slowly after become stable Treatment • Activate EMS if condition worsens o Complete loss of consciousness o Unstable vital signs • Re-evaluate diagnosis o Hypoglycemia o Seizure o CVA o Cardiac Arrest Cerebrovascular Accident (Stroke) 7 12/11/2013 Types Definition • Onset of a focal neurologic deficit or abnormality • Decrease in blood flow to a specific area of the brain • Lasts from a few minutes to hours • Cerebral thrombosis – Blockage in arteries • Cerebral hemorrhage – Aneurysm or other weakened area of an artery that burst Causes/Risk factors Knowing Signs of Stroke • Thrombosis • Will help you act faster in response • Minimize damage to the brain, improve chances of recovery- and even save your patient’s life – High cholesterol – DM – CAD, PAD • Hemorrhagic – – – – Hypertension Aneurysm Illegal drug use Trauma Cincinnati Stroke Scale Management • • • • • • Terminate procedure Oxygen by mask or nasal cannula Keep patient’s head slightly elevated Place patient on cardiac monitor Check vital signs frequently Activate EMS 8 12/11/2013 Prevention Management - Advanced • 250 ml bolus of normal saline (NS) or lactated Ringer’s (LR) if the patient’s blood pressure is low • Do not treat blood pressure unless it is 220/120 if so aim is to bring it down slightly and slowly • ACLS as appropriate • Transport to hospital capable of fibrinolytic therapy • Review patients history • Take blood pressure before treatment – Ischemic CVA Management • • • • • • Terminate procedure Supine position Ensure patient safety Establish airway Monitor vital signs 100% oxygen • • • • • • • • • • • • Syncope Brain Tumor Head injuries Stroke Electrolyte imbalance Elevated body temperatures Brain infections (e.g., meningitis) Hypoglycemia (very low blood sugar) Medication or alcohol withdrawal Administration of local or general anesthesia Cocaine and heroin abuse Antipsychotics and some asthma drugs Seizure Disorder Definition • Abnormal electrical activity in the brain • Change or loss of consciousness and involuntary muscle spasms called convulsions. • Sudden onset with variation in duration and severity. Causes 9 12/11/2013 Types Generalized Seizures (Produced by the entire brain) 1. "Grand Mal" or Generalized tonic-clonic 2. Absence 3. Myoclonic 4. Clonic 5. Tonic 6. Atonic Types Partial Seizures (Produced by a small area of the brain) Symptoms Unconsciousness, convulsions, muscle rigidity Brief loss of consciousness Sporadic (isolated), jerking movements Repetitive, jerking movements Muscle stiffness, rigidity Loss of muscle tone 1. Simple (awareness is retained) a. Simple Motor b. Simple Sensory c. Simple Psychological 2. Complex (Impairment of awareness) 3. Partial seizure with secondary generalization Management – Early • Terminate procedure • Protect patient • Place patient in the supine position • Loosen clothing • Relocate instruments/supplies • Establish airway • Position head on side • Suction mouth Management - Advanced • With continued seizures, consider IM benzodiazepine (Ativan) • Establish IV if possible – Diazepam(Valium)- 5mg/minute I.V up to 10 mg – Midazolam(Versed) - 3mg/minute I.V. or I.M. up to 6mg Symptoms a. Jerking, muscle rigidity, spasms, headturning b. Unusual sensations affecting either the vision, hearing, smell taste, or touch c. Memory or emotional disturbances Automatisms such as lip smacking, chewing, fidgeting, walking and other repetitive, involuntary but coordinated movements Symptoms that are initially associated with a preservation of consciousness that then evolves into a loss of consciousness and convulsions. Management – Early • • • • • • Apnea >30 seconds-establish basic life support Monitor vital signs Monitor vital signs and record in writing 100% oxygen by mask Observe in office for minimum of 1 hour after seizure Consult with physician Management - Advanced • Activate EMS • Observe patient following a grand mal seizure for depressed respirations • Support respiration during the recovery period (postictal state- period of time immediately following a seizure during which the patient will be confused and lethargic) 10 12/11/2013 Prevention • For known epileptics, check medication compliance • Limit the amounts of precipitating drugs to the lowest effective dose to allow adequate results • Avoid rapid injection of local anesthetic • Calculate the maximum dose prior to initiating the procedure • Aspirate prior to injection to avoid intravascular injection • Consider diazepam instead of midazolam in I.V. sedation cases Local Anesthetic Maximum Doses Maximum Dosage mg/kg mg/lb Maximum total dosage Carpules mg/carpule 7 3.2 500 mg 8 34 - 36mg 3% Mepivacaine plain (Carbocaine) 4.4 2.0 300 mg 5 51 - 54mg 4% Articaine 1:100,000 epi (Septocaine) 7.0 3.2 500 mg 6 68 - 72mg 4% Prilocaine plain (Citanest) 6.0 2.7 400 mg 5 68 - 72mg 0.5% Bupivacaine 1:200,000 epi (Marcaine) 1.3 0.6 90 mg 10 8.5 - 9mg Anesthetic 2% Lidocaine 1:000,000 epi (Xylocaine) Adapted from Stanley Malamed, Handbook of Local Anesthesia, Fifth Edition Respiratory Emergencies • • • • Dyspnea Airway Obstruction Hyperventilation Syndrome Asthmatic Attack / Bronchospasm Dyspnea Dyspnea • • • • Establish airway 100% oxygen Monitor Vitals Treat underlying cause Definition • Sensation of labored, difficult, and uncomfortable breathing. • Due to inadequate control of respiration, oxygenation, and ventilation 11 12/11/2013 Causes • Heart disease • Chronic obstructive pulmonary disease (asthma, COPD, emphysema, chronic bronchitis) • Anxiety/hyperventilation • Aspiration • Lung infection • Pulmonary embolism Signs and Symptoms • Sensation of not getting enough air • Breathing is shallow and slightly labored • Difficulty breathing at rest or after mild exertion • Unable to speak in complete sentences • Chest tightness • Severe wheezing • Anxiety, fear, agitation, restlessness • Extreme drowsiness Treatment • • • • Establish and maintain airway Assist ventilation as necessary 100% oxygen Monitor Pulse oximeter Blood pressure Cardiac status • • Identify underlying cause and treat accordingly Transport unstable pt. to Emergency Room Airway Obstruction • • • • Upright position Pack off surgical site Suction oropharynx Determine if airway obstructed • Heimlich maneuver, if indicated. Airway obstruction Definition • Bronchoconstriction, secretions, or solid material causing decreased or absence of ventilatory movement. 12 12/11/2013 Causes Signs / Symptoms • • • • • • Choking Gagging Violent expiratory effort Substernal notch retraction Cyanosis Rapid pulse initially then decreased pulse, respiratory arrest, cardiac arrest • Airway obstruction causes HYPOXIA (deficiency of oxygen in body tissue) which leads to cardiovascular complications • Respiratory arrest • Cardiac arrest • Posterior displacement of the tongue due to loss of tone of pharyngeal muscle secondary to deep anesthesia and / or sedation. • Foreign body on larynx and pharynx – secretions or solid material. Treatment - Early • • • • Treatment - Advanced Position patient upright or comfortable position Pack off surgical site Suction oropharynx Digital traction of tongue with: - Gauze - Tongue Forceps - Hemostat - Suture IF NO SUCCESS AT CLEARING AIRWAY, AND IF PATIENT LOSES CONSCIOUSNESS: • Place patient supine • Chin lift- jaw thrust • Tilt head backwards and continue to attempt to open airway • Check for respiratory sounds; ventilate of possible • Perform abdominal thrust if no airflow with ventilations Heimlich Maneuver • Stand behind patient • Place fist of one hand slightly above patient’s navel • Grasp fist with other hand • Give quick upward thrusts into abdomen (chest thrust over sternum if pregnant or obese) • Continue until object is expelled or patient becomes unconscious If patient is unconscious • • • • Activate 911 Positive pressure ventilation Endotracheal intubation Cricothyroidotomy 13 12/11/2013 Prevention • Proper placement of throat pack • Preoperative removal of potential foreign bodies (dentures, partials, tongue piercings, secretions) • Adequate suctioning • Adequate visualization of operative field Follow Up • If the foreign body is not recovered or does not pass, refer patient as soon as possible for radiographic localization – PA / Lateral neck x-ray – Chest x-ray – Abdominal x-ray Basic Treatment Hyperventilation • Upright / semi-reclined position • Verbally calm / reassure patient • Rebreathing bag to reduce carbon dioxide elimination • Hold breath Definition • Patient breathes faster and deeper • Patient exhales too much carbon dioxide, causing hypocapnea • Respiratory alkalosis cerebral vasoconstriction • • • • • Causes • Stress • Anxiety Dizziness Tingling of lips/extremities Headache Weakness Fainting 14 12/11/2013 Causes • Ingestion or overdose of medications – Amphetamine – Aspirin – Beta-2 Agonist – Cocaine – Iron – LSD – Methamphetamine – Methanol SIGN/SYMPTOMS/MANIFESTATIONS • • • • Feeling of anxiety, nervousness, or tenseness Light headedness, vertigo Muscle twitching and spasm Numbness / tingling of hands, feet or around mouth • Sweating • Pounding and racing heartbeat • Chest tightness, fullness, pressure, tenderness or pain TREATMENT • Breathe deliberately and slowly “7-11” breathing – Inhale 7 seconds – Exhale 11 seconds • Breathing in bag no longer advised – Restricts inspired oxygen, worsening hypoxia Causes • Increased metabolism from – Exercise – Fever – Graves’ disease, hyperthyroidism, thyroid storm – Infection TREATMENT • Terminate treatment and remove foreign bodies from the mouth • Position patient in an upright/semireclining • Maintain patent airway • Calm patient TREATMENT - ADVANCED • If nonsedated patient fails to respond consider – Midazolam (Versed) 1-22mg slow IV – Diazapam(Valium) 5-10 mg slow IV – Methohexital (Brevital) 10 mg slow – Propofol (Diprivan) 10-20 mg slow IV • Continue to monitor vital signs • Discontinue rebreathing bag as patient’s breathing returns to normal • Activate EMS call for assistance if patient’s condition deteriorates (patient loses consciousness, vital signs unstable) 15 12/11/2013 Definition Asthma Attack • Generalized smooth muscle contraction of the bronchi and bronchioles • Restriction of inhalation and exhalation air flow • Bronchospasm – more difficult with exhalation Causes • Genetic • Environmental • Immune system – Allergens – Triggers • Sinusitis • GERD • Medication reactions (Aspirin and NSAIDS) – Samter’s triad: asthma, nasal polyposis, ASA sensitivity Treatment - Early • Patient in upright position • Monitor vital signs • Administer 100% oxygen Signs / Symptoms / Manifestations • • • • • • • • • • • • Labored breathing Expiration difficulty Diminishing respiratory status Cyanosis Decreased oxygen saturation Decreased ventilations Wheezing Chest tightness Shortness of breath Tiring quickly during exercise Anxiety Spastic cough Treatment - Advanced • Activate EMS • Bronchodilating medications o Albuterol (Ventolin) o 4-8 puffs every 20 minutes for up to 4 hours than q1-4 hours o Ipratropium bromide (Atrovent) o 2 puffs stat than every 4 hours o 0.5mL of 0.02% nebulized solution every 4 hours o Epinephrine 0.3-0.5mg 1:1000 subcutaneous every 20 minutes to max of 1gm • Prednisone 40-60mg orally 16 12/11/2013 Prevention Cardiovascular Emergencies • Thorough medical history • Angina Pectoris • Myocardial Infarction – Assess severity of asthma • • • • Last attack? How often do you use inhaler? Prior hospitalizations? Intubation required? Other medications? Definition • Chest pain or discomfort due to insufficient oxygen to the heart Angina Pectoris Causes • Narrowing or constriction or coronary arteries • Decreased blood supply/oxygen • Increased cardiac demand for oxygen (caused by cold, stress, increased heart rate) Signs / Symptoms • • • • • • Early symptoms mistaken for indigestion Pain in chest Wide differential diagnosis Heaviness or squeezing sensation Exhibits a crescendo-decrescendo pattern Key to differentiate from MI – – – – Duration of symptom History of similar symptoms Relieved by rest, nitroglycerin, or reduction of stress Angina pain usually relieved within 5-15 minutes 17 12/11/2013 Management - Early • Terminate surgery • Activate EMS if new onset or signs of hemodynamic instability • Monitor vital signs • Immediate administration of oxygen • Nitroglycerine sublingually (.2-.6mg) every 5 minutes to max 3 doses over 15 minutes if BP>90 – Vasodilatation to improve cardiac flow • Place patient in comfortable position • Loosen all clothing Management - Advanced • Aspirin, nonenteric coated-325mg orally (chewable) • MONA (Morphine, Oxygen, Nitroglycerin and Aspirin) • Transport patient to medical facility Management - Early • • • • • Continuous EKG and pulse oximeter monitoring Set up and activate automatic external defibrillator Continue dialogue with patient to reassure Quickly review medical history Second /third nitroglycerine at 5 minute intervals over 15minutes with max of 3 doses • After 3rd dose, if no relief, assume MI • Activate EMS with signs of hemodynamic instability – Unrelieved chest pain – New onset of chest pain – Pain does not subside with nitro – Pain not typical of angina pain Prevention • Consult with patient’s physician prior to tx • Use premedication for stress reduction • Consider preoperative medications – discuss with physician • Administer supplemental oxygen • Monitor vital signs • Limit amount of epinephrine used • Discuss with pt how they are feeling Definition • Inadequate blood flow and oxygen (ischemia) to the heart muscle (myocardium) resulting in irreversible injury to the myocardium MYOCARDIAL INFARCTION 18 12/11/2013 Signs/Symptoms/Manifestations Causes • Decreased oxygen flow to the heart muscle • Complete or partial blockage of the coronary arteries • New onset of chest pain • Chest pain which lasts for at least 20 minutes • Evidence of ischemia on EKG • Increased levels of cardiac enzymes • Chest pain-crushing / squeezing • Pain continues at rest Signs/Symptoms/Manifestations • Elevated or reduced blood pressure • Pain not immediately relieved by nitroglycerin • Pain may originate under sternum-may radiate to arm, neck, and mandible • Nausea / vomiting • Diaphoresis • Anxiety • Sense of impending doom • Dyspnea Management - Early • Place patient in upright/ semi-reclined position • Activate EMS • Establish and maintain airway • Administer 100% oxygen Management - Advanced • Set up automated external defibrillation • Administer non-enteric coated aspirin 325mg (chewable) • Establish I.V. access • Nitroglycerin –0.2-0.6 mg sublingually Management - Advanced • • • • Monitor vital signs / EKG Reassure patient Start ACLS if patient loses consciousness Transport patient to hospital – repeat every 5 minutes up to 3 doses over 15 minutes 19 12/11/2013 Prevention Blood Pressure Abnormalities • Identify patient at risk for myocardial infarction • Hypertension • Hypotension – Thorough medical history – Family history – Exercise tolerance • Physician consult • Consider anxiolytic night before and morning of surgery – 5-10 mg diazepam (Valium) POHS – Continue anti-hypertensive • Consider preoperative nitroglycerin if blood pressure allows or is desirable • Avoid low PaCo2 Hypertension Causes • • • • • • • Anxiety Inadequate anesthesia or light anesthesia Hypoxia Excessive or intravascular injection of vasoconstrictor Anesthetic overdose Exacerbation of essential hypertension Noncompliance with medications Hypertensive Crises Hypertensive Urgency • SBP > 180 or DBO > 110 • No end organ damage • Possible Symptoms – – – – severe headache shortness of breath nosebleed severe anxiety Hypertensive Crises Hypertensive Emergency • SBP > 180 or DBO > 110 • With symptoms of end organ damage – – – – – – – Stroke Loss of consciousness Memory loss Heart attack Damage to eyes Loss of kidney function Pulmonary Edema 20 12/11/2013 Treatment - Early • Cessation of TX • Confirm patient airway, adequacy of ventilation and give 100% O2 • Benzodiazepines for hypertension secondary to anxiety or emergence delirium • Review medications and dose given • Reassess patient • Record vital signs every 5 minutes • Check for monitor malfunctions • If using electronic monitors confirm with manual determination Treatment - Advanced • Consider activating EMS • Oral therapy Prevention • Continue anti-hypertensive drug therapy • Check compliance to medications • Consider oral antianxiety night before surgery and day of surgery • Adequate local anesthesia and pain control Definition • • • • Systolic BP < 90 mm Hg Diastolic BP < 60 mm Hg Good cardiovascular health Pathologic - inadequate blood flow to the heart, brain and other vital organs. Hypotension Causes Preoperative: • Dehydration • Poor diet • Heart problems • Blood loss • Excessive premedication or drug allergies • Orthostatic: rapid fall in blood pressure when moving from supine to upright position) 21 12/11/2013 Signs/symptoms/manifestations Causes Intraoperative: • Hypoxia • Anesthetic overdose (especially narcotics and barbiturates) • Drug allergies • • • • • • • Weakness Nausea Impending loss of consciousness Dizziness Thirst Cold, clammy, pale skin Fatigue Early Treatment • • • • • Terminate surgery Support airway, give 100% oxygen Monitor vital signs Stimulate the patient Trendelenburg position or raise legs above head • Activate EMS if condition deteriorates • Ammonia inhalant Advanced Treatment • Initial fluid bolus of normal saline solution • Ephedrine-2.5-5 mg I.V then titrate until blood pressure is stabilized – increases heart rate – causes vasoconstriction • Phenylephrine • Hypotension from narcotics – Naloxone(Narcan) 0.4 - 2 mg I.V. every 2-3 hours as needed start with lower dosage for narcotic dependent patients. Diabetic issues • Hypoglycemia • Hyperglycemia Diabetes • Type I – body cannot produce insulin – – – – Formerly known as insulin dependent DM or juvenile onset Requires insulin replacement Causes: genetic, autoimmune Diabetic ketoacidosis (emergency, LOC) • Type II – body cannot use insulin properly (insulin resistance) – – – – – Formerly known as non-insulin dependent DM or adult onset Can be combined with reduced insulin secretion Treated with oral hypoglycemics and/or insulin Causes: lifestyle, genetics Hyperosmolar hyperglycemic state 22 12/11/2013 Diagnosis Symptoms • Polyuria, polydipsia, polyphagia, weight loss, loss of strength • Bed wetting, skin infections, irritability, headache drowsiness, malaise, xerostomia • Fasting Blood Sugar (FBS) < 125 mg/dl – Current more stringent guidelines <100 mg/dl • Post Prandial (PP) < 140 mg/dl • HbA1C (4-6%) > 8% uncontrolled in the past 2-3 months Managing the Diabetic Patient • Maximum of 2 carpules in poorly controlled patient – Epi causes glycogen breakdown which increases hyperglycemia • Use full dose of antibiotics after major procedure For management of infections. • Treat only acute dental issues and delay treatment for routine procedures for poorly controlled diabetic • Control blood glucose first • A normal type 2 diabetic can undergo all dental procedures unless diabetic complication exists • Avoid chronic use of NSAIDS and Steroids Hypoglycemia Causes Definition • Reduction in blood glucose level • Blood levels of glucose drop too low to properly fuel the body • • • • • Excessive insulin therapy/oral hypoglycemics Missed/delayed meals Illness/infection Excessive exercise Alcohol ingestion 23 12/11/2013 Signs/symptoms/manifestations Signs/symptoms/manifestations Moderate(50mg/dl) Mild (<60-65mg/dl) • Cold, clammy wet skin • Extreme hunger • Nausea • Tachycardia • Numbness/tingling lips and fingers tips • Trembling • • • • • • • Signs/symptoms/manifestations Severe (<30mg/dl) • Loss of consciousness • Seizures / convulsions • Hypothermia Treatment - Early • Oral Glucose: – Regular soft drink, fruit juice – Candy, cake frosting • Eating quick sugar foods puts glucose into the blood stream in about 5 minutes • Any quick-sugar food on this list will raise blood sugar about 30mg/dl in about 15-20 min Lack of energy Irritability Restlessness Headache Dizziness Slurred speech Blurred vision Treatment - Early • • • • Stop dental treatment Placed patient in supine patient Monitor vital signs Check blood glucose <50 mg/dl, even with no symptoms Food and amount • Fruit juice and regular soda - ½ cup • Glucose tablets - 3 tablets • Glucose Gel - ½ tube • Hard Candy - 3 pieces 24 12/11/2013 Treatment - Advanced • Patient becomes unconscious: Basic life support • Patient not responding - Activate EMS Establish I.V access • 1 ampule I.V glucose (50 ml or 50% glucose solution) • Recheck blood glucose in 15 minutes • Start I.V infusion of 5% to 20% dextrose solution Prevention • Thorough medical history and physical examination • Focus on glycemic/insulin control • Maintain normal glycemic control • Avoid hypoglycemia – A little high is better than a little low • Early identification and management Treatment - Advanced Without I.V access: • 1 mg of glucagon I.M • Recheck blood glucose in 15 min • Repeat glucagon ,as needed, base on blood glucose Preoperative Insulin dependent diabetes: • Consider half dose of long acting insulin if fasting for surgery • Check blood glucose • Start I.V with D5W Noninsulin-dependent diabetes: • Discontinue oral hypoglycemic in the morning • Check blood glucose Definition • Increase in blood sugar level Hyperglycemia – 100 – 126 mg/dl: hyperglycemia – > 126 mg/dl: diabetic 25 12/11/2013 Hyperglycemic crises • Diabetic ketoacidosis – Type 1 diabetic – 5% mortality • Hyperosmolar hyperglycemic state – Type 2 diabetic – 15% mortality Signs/symptoms/manifestations • • • • • • Dry mouth Increased thirst Frequent urination Drowsiness Stomach pain Bed wetting Prevention • Check compliance with medications • Check blood glucose • Treat infections aggressively Hyperglycemic crises • Causes – non-compliance/under-treatment of insulin (DKA) – Infection – Alcohol abuse – Trauma – PE – MI Treatment - Early • Fluids/hydration • Administer insulin • Send to ED for management Allergic Reactions • Urticaria / Pruritus • Anaphylactic Shock • Epinephrine Reaction 26 12/11/2013 Definition • Inappropriate or excess immune reaction to antigen / allergen • Slow (delayed) or fast (immediate) onset • Intense itchy and erythematous plaque that occurs on the skin Urticaria / Pruritus Causes • Allergic response to: o Medications o Latex o Environment o Food Signs / Symptoms / Manifestations • Urticaria (wheal / flare) o Face, trunk, extremities o Blanching o Hives • Pruritus o Mild to severe itching Signs / Symptoms / Manifestations • Angioedema o Face, lips, perioral tissues o Edema o Lesions (painful or burning) Treatment - Early • Upright / semi-reclining position • Administer oxygen • Monitor pulse, blood pressure and PaO2 • Erythema o Generalized or localized o Hives o Redness 27 12/11/2013 Treatment - Advanced • • • • Unsure – activate EMS Monitor vital signs Withdraw drug in question Benadryl (diphenhydramine) o 25-50mg PO every 4-6 hours (max 300 mg/day) o 25-50mg IV/IM every 2-4 hours (max 400 mg/day) Treatment - Advanced • Epinephrine – Severe reactions – See anaphylactic reactions – 0.3-0.5mg (1:1,000) IM • Oral Benadryl 25-50mg PO every 6-8 hours for 3 days • More severe reactions Prevention • Thorough history • Avoid known allergens Anaphylactic Shock Causes Definition • Immediate hypersensitivity • Sudden and severe allergic reaction • Characterized by – Cardiovascular collapse (severe hypotension) – Respiratory compromise (bronchospasm) • Allergic response to: o Medications o Latex o Environment o Food 28 12/11/2013 Signs / Symptoms / Manifestations • Onset Signs / Symptoms / Manifestations • Skin – Injectable drugs: 5-30 minutes – Oral ingestion: up to 2 hours – Flushed face (early symptoms) – Rash – Urticaria (nose / hands) – Tingling (lips, axilla, groin, hands, feet) – Angioedema (tongue / oropharynx) Signs / Symptoms / Manifestations Signs / Symptoms / Manifestations • Respiratory – – – – – – – – • CNS – Diaphoresis – Impending doom – Altered level of consciousness – Seizure – unconsciousness – Incontinence Apnea (without breathing) Dyspnea (shortness of breath) Dysphagia (difficulty swallowing) Labored breathing Coughing Dysphonia (change in voice) Inspiratory stridor Wheezing Treatment - Early Signs / Symptoms / Manifestations • CVS – Cyanosis / pallor – Dizziness – Hypotension – Tachycardia to bradycardia – Vascular collapse – Cardiac arrest • • • • If suspect, ACTIVATE EMS IMMEDIATELY Supine – BLS Administer oxygen and/or ventilate Monitor pulse, blood pressure, PaO2, patient color, and verbal response – Document and record • Check patient’s history and medication record 29 12/11/2013 Treatment - Advanced • Administer epinephrine – 0.3-0.5mg (1:1,000) IM – 0.2-0.5mg (1:10,000) IV – Repeat every 10-20 minutes • Bronchospasm / laryngospasm Treatment - Advanced • Moderate to severe anaphylaxis – Prevent late-phase recurrence symptoms – Dexamethasone (Decadron): 4mg IV – Hydrocortisone: 100mg IV • Pruritus / Urticaria o Benadryl (diphenhydramine hydrochloride) o Albuterol (Ventolin) o 25-50mg IV/IM every 2-4 hours (max 400 mg/day) o 4-8 puffs every 20 minutes for up to 4 hours than q1-4 hours Treatment - Advanced • IV fluids: 500 – 1000 mL normal saline or Ringer’s lactate • Intubate or cricothyrotomy • Transfer to hospital STAT Epinephrine Reaction Symptoms • • • • • • • • • Rapid elevation in blood pressure Increased pulse rate Anxiety Tremor Treatment Position patient comfortably Administer Oxygen Reassure patient Monitor vitals (could be 20 minutes for return to normal bp) • Activate EMS if further symptoms develop or if elevated BP remains Treatment • • • • Position patient comfortably Administer Oxygen Reassure patient Monitor vitals (could be 20 minutes for return to normal bp) • Activate EMS if further symptoms develop or if elevated BP remains 30 12/11/2013 Drug Overdose Epinephrine Interactions • Hypertensive episodes associated with: – Tricyclic antidepressants (-ptyline) – Non-selective beta blockers • Local anesthetics • Sedatives/hypnotics • Narcotics Local Anesthetic Maximum Doses mg/lb Maximum total dosage Carpules mg/carpule 7 3.2 500 mg 8 34 - 36mg 3% Mepivacaine plain (Carbocaine) 4.4 2.0 300 mg 5 51 - 54mg 4% Articaine 1:100,000 epi (Septocaine) 7.0 3.2 500 mg 6 68 - 72mg 4% Prilocaine plain (Citanest) 6.0 2.7 400 mg 5 68 - 72mg 0.5% Bupivacaine 1:200,000 epi (Marcaine) 1.3 0.6 90 mg 10 8.5 - 9mg 2% Lidocaine 1:000,000 epi (Xylocaine) Local Anesthetics Maximum Dosage mg/kg Anesthetic Adapted from Stanley Malamed, Handbook of Local Anesthesia, Fifth Edition Signs / Symptoms / Manifestations • • • • • Low to Moderate Overdose Levels Confusion Talkativeness Apprehension Excitement Slurred speech Signs / Symptoms / Manifestations • • • • • Low to Moderate Overdose Levels Elevated BP Elevated HR Elevated RR Generalized stutter Twitching 31 12/11/2013 Signs / Symptoms / Manifestations • • • • • Low to Moderate Overdose Levels Restless Visual disturbances Auditory disturbances Numbness Metallic taste Signs / Symptoms / Manifestations Moderate to High Overdose Levels • Generalized tonic-clonic seizure activity followed by o Generalized CNS depression o Depressed BP, heart rate o Depressed respiratory rate Treatment - Advanced • • • • Signs / Symptoms / Manifestations • • • • Low to Moderate Overdose Levels Light-headed and dizzy Drowsy and disoriented Losing consciousness Sensation of twitching (before actual twitching is observed) Treatment - Early • Administer oxygen • Monitor vitals Sedatives / Hypnotics Activate EMS Place patient in supine position Maintain airway Manage seizures – Diazepam (Valium) 5-10mg IV • Manage postictal state • Transfer 32 12/11/2013 Signs / Symptoms / Manifestations • Decreased respiratory rate • Cyanosis • Unresponsiveness Treatment • Place patient in supine position • Maintain open airway • Administer oxygen and ventilation assistance if needed • Monitor vital signs • Activate EMS • Flumazenil (Romazicon) – 0.2mg IV than 0.1mg/minute up to 1 mg Narcotic Overdose Signs / Symptoms / Manifestations • Decreased respiratory rate • Cyanosis • Unresponsiveness Treatment • Place patient in supine position • Maintain open airway • Administer oxygen and ventilation assistance if needed • Monitor vital signs • Activate EMS • Naloxone (Narcan) References • Advanced Protocols for Medical Emergencies- Lewis, McMulln; Lexi-Comp, Inc. • Dental Office Medical Emergencies- Meiller, Wynn; Lexi-Comp, Inc. • Medical Emergencies- 5th edition, Malamed- 2000 • Oral and Maxillofacial Surgery Secrets – Abubaker, 2007 – 0.4-2mg mg IV every 2-3 minutes 33