Download - IEEE Mentor

July 2012
doc.: IEEE 802.15-12-0394-00-004n
Project: IEEE P802.15 Working Group for Wireless Personal Area Networks (WPANs)
Submission Title: Overview of I2R’s Wireless Transceiver Design for MBAN
Activities
Date Submitted: July 17, 2012
Source: Dr. Sumei Sun
Contact: Dr. Sumei Sun, Institute for Infocomm Research (I2R), ([email protected]), Dr. Xiaoming Peng ([email protected])
Re:
Overview of I2R’s Wireless Transceiver Design for MBAN Activities
Abstract:
Purpose: To focus activities during the meeting
Notice: This document has been prepared to assist the IEEE P802.15. It is
offered as a basis for discussion and is not binding on the contributing
individual(s) or organization(s). The material in this document is subject
to change in form and content after further study. The contributor(s)
reserve(s) the right to add, amend or withdraw material contained herein.
Release: The contributor acknowledges and accepts that this contribution becomes
the property of IEEE and may be made publicly available by P802.15.
Submission
Slide 1
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Outline
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for Treatment
Submission
Slide 2
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for Treatment
Submission
Slide 3
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
The A*STAR Family
Institute of
High
Performance
Computing
(IHPC)
Data
Storage
Institute
(DSI)
Submission
Institute
for
Chemical &
Engineering
Sciences
(ICES)
Institute of
Microelectronics
(IME)
Slide 4
Singapore
Institute of
Manufacturing
Technology
Institute of (SIMTech)
Materials
Research &
Engineering
(IMRE)
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
A*STAR’s BEP Program
• The Biomedical Engineering Programm (BEP) is a competitive,
multi-disciplinary grant programm
• Aiming at engaging the local clinical community with engineers and
scientists to develop cost-effective innovations through a needsdriven approach that will improve patient care
• Funded by the Science and Engineering Research Council (SERC)
of A*STAR
• Supports Clinician-Engineer/Scientist collaborative research
projects with emphasis on devices, procedures, diagnosis, and
clinical systems
• The two use cases we share in this presentation are supported
under the Program.
Submission
Slide 5
Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Outline
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for
Treatment
Submission
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Introduction
• Capsule endoscopy is a technique
which facilitates imaging of the
gastro-intestinal track
• Can be used to evaluate cause of
gastro-intestinal bleeding and the
surveillance of small bowel tumor
and polyps
• Safe and well-tolerated procedure,
with low complication rates
Submission
Slide 7
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Project objective
• Develop wireless comms module for swallowable
capsule
• In-body diagnostics
Camera
Submission
26 mm
Comms &
Application
Module
Battery/
Standard
Module
Slide 8
Antenna
11 mm
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Existing Comms Transceiver
• Zarlink MICS Transceiver – ZL 70101
•
• RF Band – 402 to 405 MHz
• Max data rate – 800 kbps
• FSK modulation
• Low power
Submission
Slide 9
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Comms Requirements (1/2)
• Primary function
– Transmit up to 6 x VGA quality images per second
• Translates to 1.5 to 3 Mbps
– existing transceiver cannot achieve this data rate
• Other functionalities include:
– temperature sensing
– pH sensing
– capsule status indication
Submission
Slide 10
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Comms Requirements (2/2)
• Provide limited control of capsule (low data rate)
–
–
–
–
Toggle between sleep / active mode
Actuators control
Activation of biomarkers
Adjust image compression ratio
• RF Band – 921 to 924 MHz
– antenna more compact in 900 MHz than in 400 MHz
band
• Low power
Submission
Slide 11
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
PHY Layer Design (1/2)
• Comms receivers are typically more complex
than transmitters
• Shift system complexities to external base
station to reduce power
• Asymmetric comms link between in-body
capsule and external base station
• Modulation:
– Capsule – QPSK Tx / OOK Rx
– Base station – OOK Tx / QPSK Rx
Submission
Slide 12
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
PHY Design (2/2)
• Error correction:
– Capsule
• Reed-Solomon (255, 239) encoder
• 1/3 repetition code decoder
– Base station
• 1/3 repetition code encoder
• Reed-Solomon (255, 239) decoder
• Data rates:
– Capsule to base station – 3 Mbps
– Base station to capsule – 50 kbps
Submission
Slide 13
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Antenna Design
• Capsule
– Coil antenna
– Radiation – Omni-directional
– Dimension – 5 x 5 x 5 mm3
• Station
– Patch antenna
– Radiation - Directional
– Dimension – 100 x 100 x 4.6 mm3
Submission
Slide 14
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
The Animal Trial
The standalone
capsule
Submission
The capsule in pig’s stomach
Slide 15
Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Outline
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for
Diabetes Treatment
Submission
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Background and Motivation
• 286 million diabetics worldwide, 400 million by 2030
• ~10% of the Singapore population has diabetes
• 7th leading cause of death in Singapore ,
• ~US$116 billion was spent on the direct medical cost for
diabetes in 2007 (in US alone)
• All Type I and ~30% of Type 2 diabetics require insulin therapy
• Painful fingerpricks (blood glucose testing) and insulin injections
• Psychological aversion to the therapy  non-compliance (as
high as 50%)
– Non- compliance increases the risk of developing systemic sequelae
Submission
Slide 17
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Some Available Advanced
Solutions
• Implanting of semi-permanent glucose-sensing
and insulin-delivery components
- Medtronic, Johnson & Johnson, Roche, Abbott,
and Animas
• New forms of insulin
- Exubera by Pfizer, an inhaled form of insulin
(withdrawn due to fears of pulmonary side effects)
Submission
Slide 18
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Our Objective
• Develop a proof-of-concept prototype for implantable close-loop
glucose control
– A closed-loop glucose regulation algorithm
– A bench model for testing and developing the above algorithm
– A fail-safe system to prevent hypoglycaemia based on graded
alarms and glucose-insulin co-infusion
– A wireless transceiver
– A power management module with embedded wireless inductive
power charging capabilities
Submission
Slide 19
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Lab Bench Prototype
Platform for Base Station
(external unit)
Submission
Platform for Implantable Device
(internal unit)
Slide 20
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Lab Bench Prototype
Base Station Communicating with Implantable unit
Submission
Slide 21
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Validation of Control Algorithm
Case 1 - Type 1 Patient
Cases 2 and 3 – A Type 2 Patient
monitored in March and April 2011
Modeled glucose level and clinical data
were shown in the top panel; and in the
bottom panel the red dash curve and the
green solid line represented glucose intake
rate Gin (mg/dL) and insulin injection u
(mU/min), respectively.
Submission
Slide 22
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Test and Trial with Pork Meat
Submission
Slide 23
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Prototype for Upcoming Animal
Test
Submission
Slide 24
Sumei Sun, I2R
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Power Management
• Energy consumption profiling
– Conducted experiment on energy consumption profile of the
implant device in various operation modes
– Will be used to further optimize power management mechanism
• Energy harvesting/charging mechanism
– Conducted experiments on resonant-based wireless power
transfer/charging
– Design is on-going
Submission
Slide 25
Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Summary and discussions
• Two wireless transceiver design projects have
been presented
– One with short-life cycle, high data rate
– One with long life-cycle, moderate or low data rate
• Higher and higher demand for intelligent
healthcare/lifesyle management
– Calling for unified/inter-operable communication standard
Submission
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Thank You!
Q&A
Submission
Slide 27
Sumei Sun, I2R