Download S1 Text.

Table A
Clinical
symptoms
Onset date
Days after
symptoms onset *
Days after rash
onset *
Rash duration
Rash type
Low grade fever
(duration)
Headache
Retro-orbital pain
Photophobia
Fatigue/ malaise
Myalgia
Arthralgia
(region)
Patient
1
01/11/16
2
01/24/16
3
01/22/16
4
01/31/16
3
2
5
1
<1**
1
1
1
5 days
6 days
Macular and
maculopapular
+
(2 days)
+
+
2 days
2 days
Maculopapular
Maculopapular
Macular
+
(wrist and
elbows)
-
-
+
(4 days)
+
+
NI
+
+
+ (large and
small joints)
-
Arthritis
Anorexia
+
Nausea/ vomiting
+
Diarrhea
Abdominal pain
Dysuria
Bleeding/ petechia
Dizziness/ light
headedness
Pruritus
+
+
+
Paresthesias
+
Conjunctivitis
Edema
+
(local/site)
(hands)
Lymphadenopathy
(local/ site)
Enanthem
NI
NI
Respiratory
symptoms
Jaundice
Seizures
* Regarding the date of sample collection; **the collection date was in the first
day of rash manifestation
Table B
Clinical
symptoms
Onset date
Days after
sypmtons onset *
Days after rash
onset *
Rash duration
Patient
5
01/26/16
6
01/26/16
7
01/31/16
8
01/31/16
9
01/28/16
2
3
1
2
5
2
<1
1
2
2
20 days
4 days
5 days
6 days
3 days
Rash type
Macular
Low grade fever
(duration)
Headache
Retro-orbital pain
Photophobia
Fatigue/ malaise
Myalgia
Arthralgia
(region)
+
+
+
+
+
-
Arthritis
Anorexia
Nausea/ vomiting
Diarrhea
Abdominal pain
Dysuria
Bleeding/ petechia
Dizziness/ light
headedness
Pruritus
Paresthesias
Conjunctivitis
Edema
Lymphadenopathy
(local/ site)
Enanthem
+
+
+
-
Maculopapular
+
(1 day)
+
+
+
(wrists,
ankles,
knees,
hands)
+
+
-
Maculopapular
-
Macular
and
maculopapular
+
(2 days)
+
+
+
-
Maculopapular
+
+
+
+
-
+
(large
and small
joints)
-
-
-
-
+
-
-
-
-
+
+
+
+
(feet and
hands)
+
+
+
+
-
+
-
+
+
+
(hands)
-
+
-
-
-
-
+
(cervical)
-
-
-
-
+
(Cervical
and
auricular)
-
Respiratory
+
+
symptoms
Jaundice
Seizures
* Regarding the date of sample collection; **the collection date was in the first
day of rash manifestation
Table C
Socialdemographic
data
Patient
1
2
Gender
female
female
Age
36
30
Gestational age
18
33
(weeks)
Family
members
illness
Partner illness
Repellent spray
+
+
use
Previous DENV
+
infection
Domicile in Rio
Duque de Nova Iguaçu
de Janeiro
Caxias
State
NA – not applicable; NI- not informed
3
4
male
24
female
42
NA
21
+
-
NI
NI
+
NI
-
Rio de
Janeiro
Duque de
Caxias
Table D
Social
demographic
data
Gender
Age
Gestational age
(weeks)
Family members
illness
Partner illness
Repellent spray
use
Previous DENV
infection
Domicile in Rio de
Janeiro State
Patient
5
6
7
8
9
female
30
male
68
female
20
female
27
female
22
NA
NA
17
21
20
-
+
-
-
-
-
-
-
-
-
+
-
+
+
+
+
+
-
+
-
Rio de
Janeiro
Rio de
Janeiro
Rio de
Janeiro
Duque
de
Caxias
Rio de
Janeiro
NA – not applicable; NI- not informed