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Enhanced Sympathetic and Ventilatory Responses to Central Chemoreflex Activation in Heart Failure by Krzysztof Narkiewicz, Catherine A. Pesek, Philippe J. H. van de Borne, Masahiko Kato, and Virend K. Somers Circulation Volume 100(3):262-267 July 20, 1999 Copyright © American Heart Association, Inc. All rights reserved. ECG tracings and sympathetic neurograms at baseline and during third minute of hypercapnia. Krzysztof Narkiewicz et al. Circulation. 1999;100:262-267 Copyright © American Heart Association, Inc. All rights reserved. Changes in minute ventilation (Ve), mean arterial pressure (MAP), HR, and MSNA during hypercapnia in control subjects (○) and patients with CHF (•). Krzysztof Narkiewicz et al. Circulation. 1999;100:262-267 Copyright © American Heart Association, Inc. All rights reserved.