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APC Postgraduate (PhD) Position Job Posted: Closing Date for Applications: 29 Aug 2016 School: Medicine (Department of Pharmacology & Therapeutics/ Department of Urogynaecology/ APC Microbiome Institute). College: Medicine & Health Contract Type: Fixed Term Whole-Time Job Type: Research Salary: See below APC Postgraduate Position The APC Microbiome Institute (APC) was formed in 2003 with funding from Science Foundation Ireland and in conjunction with key industry partners. It represents a seamless collaboration between UCC, Teagasc, Moorepark and CIT. It is widely recognised that the gut microbiota plays an important role in human health and has become one of the most dynamic, complex and exciting areas of research in both food and pharmaceutical arenas. The postgraduate position is open to candidates who meet residency requirements in Ireland or the EU. The studentship comprises an annual stipend for three years, in addition to fees at the EU level (approximately €6,000 per year). The current stipend is €18,000 per annum. PhD position: The student will be a registered student in the Department of Pharmacology & Therapeutics. The student will be associated with the APC Microbiome Institute, UCC. Unique ref no. H14 Title: Exploring the Bladder Microbiome in Health and Disease Description: Notably, the bladder was not included in the Human Microbiome Project. This in combination with the incorrect assumption that “culture-negative” status of urine equates to sterile has resulted in a delay in the characterization of the bladder microbiome in health and disease. However, it is now clear that a bladder microbiome can be detected and that it is altered in bladder disorders. One such disorder is bladder pain syndrome (BPS). BPS is acknowledged as a major health issue which significantly overlaps with other functional pain disorders, most notably irritable bowel syndrome (IBS) in which we have significant pre-existing expertise Therefore, the specific research aims are: (1) to recruit patients with bladder pain syndrome and assess their disease severity and comorbidities using well validated clinical questionnaires; (2) molecularly characterise the urinary microbiomeand host bladder mucosa Our overall aim is to characterise the urinary microbiome and mucosal biopsies from patients with bladder pain syndrome and control subjects stratified by psychiatric and gastrointestinal comorbidities. Principal Investigators – Dr. Niall Hyland (APC/UCC), Dr. Barry O’Reilly (APC/CUMH) Informal queries to Dr. Niall Hyland at [email protected] Key Duties and Responsibilities To conduct a specified programme of research under the supervision and direction of a Principal Investigator. To work with the project partner and other partners / collaborators in achieving the research goals. To participate in the dissemination of the results of the research (oral and written) in which you are engaged, as directed by the Principal Investigator. To contribute and produce high quality peer reviewed publications and other outputs. To present research progress and project outcomes at project meetings and relevant conferences. To engage in the wider research and scholarly activities and educational and outreach programmes of the APC. Criteria An upper second class or first class honours BSc degree and/or a MSc degree in Biomedical Science, Pharmacy. Microbiology, Molecular Biology, Genetics, Biochemistry or related discipline Experience in microbiology desirable Highly motivated individual with a keen interest in molecular biology and clinically orientated research. Have excellent laboratory skills, organizational and communication skills, report writing and data analysis An ability to work independently to a tight schedule to deliver the milestones and deliverables as set out in the project proposal Have the ability to work effectively as part of a team to achieve results within the time frame of the project. To Apply: Applications should include a covering letter, a detailed CV and the names and contacts of 2 referees and should be sent by email as indicated below, quoting the Unique reference no: H14 Applications will be accepted until August 29th 2016 Applications to [email protected] (please cite the unique position ref in the subject of email) University College Cork is an Equal Opportunities Employer.