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REPRODUCTIVE AND DEVELOPMENTAL BIOLOGY (Level 2, 4 CU) a. Brief Course Description This course will deal with the importance and significance of reproduction, embryology, gametogenesis, the role of hormones, fertilisation, implantation and type of placentas. b. Course objectives By the end of the course, the student should be able to: Give the importance and significance of reproduction and sex determination Describe the process of, blastulation and gastrulation Compare and contrast the developmental stages among amphioxus, frog , pig and man Identify the different embryonic membranes and where they are found Examine and describe the changes in development of in the chick Describe the development of the man embryo from fertilization till birth c. Detailed Course Description: Embryology of Amphioxus , development of Amphioxus (4 hrs) Embryology of Amphibia (4 hrs) Embryology of chick, the establishing of the body and laying down of the organ systems as exemplified by the chick (14 hrs) From the primitive streak stage to the appearance of Somites. (2 hrs) The notochord, the primitive streak as the centre of early growth, regression of the primate streak, caudal growth and cephalic precocity, growth of the endoderm and establishment of the primitive gut. (9 hrs) Growth and early differentiation of the mesoderm and formation of the neural plate.(1 hr) Formation of the blastula in Amphioxus, Amphibia, chick and mammals (2 hrs) Gastrulation in Amphioxus, Amphibia, chick and mammals.(2 hrs) Formation of the germ layers and origin in Amphioxus, Amphibia, chick and mammals (2 hrs). Organizers , induction , transplants and heteroblastic grafting (1 hr) Types of placentas: Development of 7mm pig embryo, external morphology internal morphology, spinal nerves, neural tube (2 hrs) Human development: human embryos and multiple births (2 hrs) Practicals (30 hrs) d. Mode of delivery: Lectures, assignments, tutorials and practicals Assessment: Practicals, assignments and tests (40%) and examination (60%)