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Leader:
Course:
Instructor:
Date:
Cell Signaling
Supplemental Instruction
Iowa State University
Kali D
BIOL 212
Dr.Kukday
10/8/14
Warm up:
List 3 environmental conditions that our bodies need to respond to.
Explain the difference between intracellular communication and intercellular communication.
Application:
1. Receptors can be
or
. (fill in the blank)
2. Can large, hydrophilic ligands enter the cell? (yes/no) If no, how is their signal relayed?
3.What are the three types of cell surface receptors? How are their signals transduced? What are
their protein targets?
A)
B)
C)
4. Explain the signaling pathway for EGF.
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
Epinephrine?
What are the differences between the two pathways?
5. What is the difference between estrogen-mediated response and glucocorticoid meditated
response?
6. What is the first step in apoptosis?
What is the role of caspases?
What is cAMP? Why is it important in signal transduction?
Videos
G-protein linked receptors http://youtu.be/xT0mAQ4726s
Enzyme linked receptors http://youtu.be/kaoRrzakjGE
Ligand gated receptors http://youtu.be/Pl7nzXaVqak