Download Integrated course of Human Physiology

Integrated Course of
HUMAN PHYSIOLOGY
European Credit Transfer and Accumulation System =
4 Hours of formal lectures 32 Hours of interactive
learning activities 16
Scientific field: Human Physiology BIO/09
Coordinator: Prof. ANTONIO COLANTUONI
Department of Clinical Medicine and Surgery, ed. 19, 9th floor, phone 0817463212
e-mail: [email protected]
Faculty
Position
Scientific Fields:
Phone
F.P.
HUMAN
PHYSIOLOGY
3212
Mon. 14:30–15:30
ed.19, 9th Floor
[email protected]
F.P.
HUMAN
PHYSIOLOGY
3225
Wed. 10:30–12:30
ed.19, 11th Floor
[email protected]
A.P.
HUMAN
PHYSIOLOGY
3233
Wed. 11.00-1300
ed.19, 11th Floor
[email protected]
Colantuoni
Antonio
Mondola Paolo
Santillo
Mariarosaria
Reception
(day/time/building)
E-mail
EDUCATIONAL OBJECTIVES
The human physiology course is focused on the study of the organ functions involved in the body system, starting
from the knowledge of organ metabolic activity, up to the dynamic integration of several organs to form a system;
The study comprises:
1) The control mechanisms of the different organ functions;
2) The regulatory mechanisms of human body integrated functions in physiological conditions;
3) The application of the general laws of physics, biophysics, chemistry, mathematics, statistics and biomedical
technology to the functions of the human body
CORE CURRICULUM
Human Physiology I program covers:
1)The study of the functioning of the heart and cardiovascular system, under physiological conditions and in
response to environmental stress;
1) The study of the essential mechanisms of breathing and its control under physiological conditions as well as in
different environmental conditions;
2) The study of the functional mechanisms of kidney under physiological condition, and their involvement in the
processes of acid-base balance and body fluid volume regulation;
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3) The study of the mechanisms involved in digestion and absorption of food nutrients; to know the metabolism and
secretion of abdominal organs;
4) The study of the content in nutrients of food and their application to the healthy balanced diet under
physiological condition;
5) The study of the functions of blood and body fluids.
PRELIMINARY KNOWLEDGE
A basic knowledge on cell biology and human anatomy
PROPAEDEUTIC COURSE
EXAMS
A test with multiple choice questions on the arguments listed in the core curriculum is preliminary to the oral
examination. The test must be passed (almost 18/30) for the access to oral examination.
TEXTBOOKS
1)Berne & Levy Physiology, 6th Updated Edition by Bruce M. Koeppen, Bruce A. Stanton Elsevier
2)Medical Physiology, 3rd Edition by Walter F. Boron (Autore), Emile L. Boulpaep Elsevier
DIDACTIC ACTIVITY C.I. HUMAN PHYSIOLOGY
WEEK
TIME
LESSONS
Cellular membranes and transmembrane transport of solutes
and water. Hemorheology and fluidodynamics: the
1°
14:30
fundamental principles. Hemodynamics: Poiseuille’s law and
6-10 March
15:30
blood viscosity. Homeostatic function of blood. Hemostasis
and blood coagulation.
2°
13 -17 March
3°
20 -24 March
4°
27 - 31 March
5°
3-7 April
6°
10 - 12 April
14:30
15:30
Electrical activity of the heart. Seno atrial node: pacemaker
cells. Ventricular myocytes. Atrial, atrial-ventricular and
ventricular conduction. Electrocardiography: standard limb
leads
14:30
15:30
The cardiac pump. Cardiac chambers. Cardiac valves. Cardiac
cycle. Measurement of cardiac output. Regulation of cardiac
output. Frank-Starling’s law of the heart
14:30
15:30
Regulation of the heartbeat: nervous control of heart rate.
The arterial system; regulation of arterial blood pressure.
14:30
15:30
The microcirculation and lymphatics. The peripheral
circulation and its control. The peripheral circulation and its
control
14:30
15:30
Special circulation: coronary blood flow. Cutaneous
circulation; skeletal muscle circulation; cerebral circulation
PROFESSORS
Colantuoni
Colantuoni
Colantuoni
Colantuoni
Pohl
Colantuoni
2
WEEK
TIME
7°
19 -21 April
13:30
14:30
8°
24 - 28 April
9°
2-5 May
10°
8-12 May
11°
15-19 May
12°
22-26 May
13°
29 May-1 June
14:30
15:30
14:30
15:30
14:30
15:30
14:30
15:30
14:30
15:30
13:30
14:30
LESSONS
Respiratory system: Structure and function of the respiratory
system. Blood supply to the lung. Pulmonary ventilation:
muscles of respiratory.
Mechanical properties of the lung and chest wall: static and
dynamic. Pulmonary interstitial fluid dynamics: edema.
Ventilation and perfusion relationships. Oxygen and carbon
dioxide transport.
Control of respiration: chemical and nervous. High altitude
acclimatization.
Elements of renal function: structure and functions of the
kidneys and urinary tract. Glomerular filtration and
autoregulation. Renal clearances. Solute and water transport
along the nephron: tubular functions.
Henle’s loop. Distal tubule and collecting duct. Control of body
fluids, osmolality and volume: concentration and dilution of
urine. Control of extracellular fluid volume and regulation of
NaCl excretion. Role of the kidney in the regulation of acidbase balance.
Gastro-intestinal system: Motility. Salivary secretion; gastric
secretion; pancreatic secretion; function of the liver: bile
secretion; intestinal secretion. Digestion and absorption of
carbohydrates, proteins and lipids. Intestinal absorption of
salts and water.
Absorption of vitamins. Absorption of bile acids. Regulation of
secretion and motility of gastrointestinal system. Principles of
human nutrition. The resting energy expenditure. The exercise
induced metabolic activation. Nutrition and lifestyle along the
different periods of life. Nutrition during pregnancy, delivery
and lactation.
PROFESSORS
Santillo
Mondola
Mondola
Mondola
Mondola
Mondola
Mondola
3