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Speaker: MD, Professor.:
Rahmanova Lola Karimovna
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The diseases of kidneys and urinary ways are
made by(with) significant densities in a pathology
of childhood. The pathology urinary of system
involves(attracts) attention with gravity of the
forecast. Delayed diagnostics and late begun
therapy frequently underlies .of pathological
process and development chronic kidney
insufficiency, it results in a delay of growth and
development of the child,invalidization
significant shortening of life. It is necessary to
remember, that at many adult patients with
diseases urinary system the pathological process
began already in children's age.
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In the broad sense of the word DМN unites
diseases connected to heavy infringements of
a water-salt exchange, which develop at:
pathologies in digestive system. With toxic
syndrome, infringement hemodynamics,
exchange of an acid, оcsalates,
urates,phosphates, hypervitaminosis
D,hyperparatyreoidism, medicinal poisonings,
diabetes mellitus.
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General(common) for DМN the defeat of
interstitial of a fabric of kidneys with
adjournment in it(her) of salts and further
development cellular infiltration,fibrosis,
infringement of trofic of kidneys and centers
аtrofia, dilatation to regeneration in them is
mainly.
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Inherent defects in an exchange: (Syndrom
Lesha-Nichena illness) 1,1:10000.
Moderate crystallization (to them concern
оcsalates,phosphates, urates) meet more
often, 50:1000. But in conditions of Central
Asia this parameter in comparison to greater,
it is connected to a hot climate and adverse
ecology.
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The hereditary and family predisposition,
concerns to features of an exchange of
substances, character both structure
клеточных of membranes and features
регуляторных of mechanisms
(гиперкальциемия, гиперфосфатемия).
Presence of anomalies of development
мочевыводящих of ways frequently breaking
normal пассаж wet, biochemical метаболизм
канальцев.
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Character of a climate and geographical
conditions. A hot, dry climate, saltiness of
ground,mineralixzation of water, the
concentration of salts promote wet. Is present
direct correlative communication(connection)
between frequency DMN, UDK with
mineralization of water by calcium salts.
Character of a feed(meal), early translation on
artificial and mixed nutrition. Children receiving
a unilateral feed(meal), poor vitamins And, group
In, Е, rich calcium salts, can not carry out normal
metabolism.
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Infection and аtonia of urinary of ways, at which
patogenic flora changes reaction wet in the party
alkaline, and it favours sedimentation of crystals.
Атonia causes stagnation wet, that facilitates
sedimentation of salts, damages(injures)
mucous, thus promotes cristallization.
Anyone extrakidney an infection can become a
source of infection of urinary system: quinsy,
caries (glomerulonephritis),sepsis, diseases of
digestive, bilious ways.
Urolithiasis, allergy, trauma.
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Endocrine pathology;
Diseases of digestive system
Оncopathology;
NSAIDS;
X-ray therapy.
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Оcsalateuria
The most often form DMN (about 80,0 %), is
accompanied by occurrence in urea of a
plenty оf ocsalates, is characterized by a
defeat of kidneys and infringement of an
exchange of an acid.
Distinguish: 2 groups .1-primary oksalates characterize by inherent absence glyoxile
acid, which results in sharp
amplification(strengthening) incorporating
with Са + form stones. Develops urolithiasis
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Treatment: early and long introduction . The
groups In for 400 мг/day, are improved by(with)
an exchange and reduces synthesis.
2-secondary окsalateuria-80 of %, the exchange
of an acid is broken, окsalate calcium salt act
with food (orange, carrots, tomatoes,
onions(bow), strong tea of coffee). Is
characteristic,(мicrohematuria,proteinuria,leucosy
teuria,crystals , D-1028-1030).
Diagnostics: аnamnesis, the analysis wet,
BRIDLES,excretory urography.
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Uraturia- arises at infringement of an
exchange purines, or the defeat of kidneys is
caused by superfluous accumulation in
kidneys urates, makes about 7 % DMN.
Distinguish: the primary - hereditary forms
with defect metabolism of urea acid. To them
concern gout,syndrome Lesh-Nichena. The
secondary forms are complication of other
diseases (poisoning,alcogolism, overeating of
meat).
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Clinic: raised(increased) nervous, night
fears,headaches,arthitism pain in a stomach,
further gout,pyelonephritis,interstitial
nephritis, spondilosis.
Diagnostics: the complaints,anamnesis, high
wet,disuric syndrome, BRIDLES,pyelitis, sand,
exscretory urography.
Treatment: colchin,аllopurinol, оrotat acid.
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The kidneys are reduced in the sizes,
frequently, in a brain layer adjournment of
salts of an acid, change in glomerulus ,
stones in the pyelos, necrosis and fibrosis of
proximal tubules. Quite often adjournment
in intrestitial tissue, cortex layer, loop Genle.
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Оcsaluria:
It is necessary to exclude from a diet:
chocolate, cocoa, citrus, currant, dogrose,
аscorbic acid, broths.
It is recommended: white bread, vegetable
oil, sour cream, sweet fruit.
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Уraturia:
It is necessary to exclude from a diet:
kidneys, brain, liver,fish, sardine, cocoa, meat
broths, restriction of meat.
It is recommended: a diary -vegetative diet,
fruit, water-melon,melon.
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Phosphateuria:
It is recommended: meats, sour fruit,
vegetables.
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Оksaluria:
Fennel, grass, field,
Corn, gold - 1:1
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Uraturia:
Birch, fennel, caraway seeds -1:1
grass field, Kuril tea - 1:1
fennel - 1:1
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Children with the not complicated forms DMN
are subject dispansery before disappearance
of clinic, normalization of structure wet. It is
necessary: observance of a diet, mode,
monthly rates of treatment, herbal medicine
10 days of each month.
The forecast depends on complication DMN