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8.3 DNA Replication KEY CONCEPT General Description: DNA replication copies the genetic information of a cell. 8.3 DNA Replication Replication copies the genetic information. • A single strand of DNA serves as a template for a new strand. • The rules of base pairing direct replication. • DNA is replicated during the S (synthesis) stage of the cell cycle. • Each body cell gets a complete set of identical DNA. 8.3 DNA Replication Proteins carry out the process of replication. • DNA serves only as a template. • Enzymes and other proteins do the actual work of replication. • Process 1. Enzymes unzip the double helix. 2. Free-floating nucleotides form hydrogen bonds with the template strand. nucleotide The DNA molecule unzips in both directions. 8.3 DNA Replication 3. DNA polymerase enzymes bond the nucleotides together to form the double helix. 1. Sugar Phosphate Backbone 4. new strand 2. Nitrogen bases 3. DNA polymerase 8.3 DNA Replication 4. Two new molecules of DNA are formed, each with an original strand and a newly formed strand. • DNA replication is semi-conservative, meaning one original strand and one new strand. new strand original strand Two molecules of DNA 8.3 DNA Replication Replication is fast and accurate. • DNA replication starts at many points in eukaryotic chromosomes. There are many origins of replication in eukaryotic chromosomes. • DNA polymerases can find and correct errors. 8.3 DNA Replication • http://www.youtube.com/watch?v=z685FFqmrpo