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8.3 DNA Replication
KEY CONCEPT
General Description: DNA replication copies the
genetic information of a cell.
8.3 DNA Replication
Replication copies the genetic information.
• A single strand of DNA serves as a template for a new
strand.
• The rules of base pairing direct
replication.
• DNA is replicated during the
S (synthesis) stage of the
cell cycle.
• Each body cell gets a
complete set of
identical DNA.
8.3 DNA Replication
Proteins carry out the process of replication.
• DNA serves only as a template.
• Enzymes and other proteins do the actual work of
replication.
• Process
1. Enzymes unzip the double helix.
2. Free-floating nucleotides form hydrogen bonds
with the template strand.
nucleotide
The DNA molecule
unzips in both directions.
8.3 DNA Replication
3. DNA polymerase enzymes bond the nucleotides
together to form the double helix.
1. Sugar
Phosphate
Backbone
4. new strand
2. Nitrogen bases
3. DNA polymerase
8.3 DNA Replication
4. Two new molecules of DNA are formed, each with an
original strand and a newly formed strand.
• DNA replication is semi-conservative, meaning one
original strand and one new strand.
new strand
original strand
Two molecules of DNA
8.3 DNA Replication
Replication is fast and accurate.
• DNA replication starts at many points in eukaryotic
chromosomes.
There are many origins of replication in eukaryotic chromosomes.
• DNA polymerases can find and correct errors.
8.3 DNA Replication
• http://www.youtube.com/watch?v=z685FFqmrpo
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