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Cultured Animal Products for Foods and Materials 2015 BIO World Congress What if animal products could We have unique capabilities to tune be made better and components of the media to give without enhanced cellharming performance. animals or the environment? STRICTLY CONFIDENTIAL 15-04-19 | 2 By 2050, the demand for animal products is projected to nearly double 9+ 7 BILLION PEOPLE 60 BILLION 100 BILLION LAND ANIMALS LAND ANIMALS BILLION PEOPLE TODAY 2050 Today, the livestock industry is already pushing planetary resource limits 38% 8% ICE-FREE LAND GLOBAL WATER >18% GREENHOUSE GASES Plus: food security, disease risk, chemicals, antibiotics, pesticides, animal welfare… Rising meat and hide prices reflect scarcity and resource limits US Hide Prices Monthly The price of meat has risen ~2.5x in the past 15 years Hide prices have fluctuated within a 4x range in the last 6 years Source: indexmundi.com Our solution: A better process for growing animal products directly from animal cells STRICTLY CONFIDENTIAL 15-04-19 | 6 Creating an integrated biofabrication platform MATERIALS Cell sourcing Cell eng. Design Cell culture Chemistry Food science FOODS Tissue eng. Material science OTHER Beginning with Materials How do we culture leather? 1 2 SOURCE CELLS GROW CELLS 3 GROW SHEETS 4 5 8 DESIGN 7 FINISH 6 TAN HIDE LAYER SHEETS FUSE LAYERS We unveiled edible prototype cultured We first unveiled edible prototype cultured meat in 2011 and cultured leather in 2013 STRICTLY CONFIDENTIAL 15-04-19 | 10 Challenges for traditional leather Bioengineering enables tunable leather Potential features include: translucency; waterproofing, biological watermarks, embedded fibers, grown patterns, large sized leather, 3D shapes, ultrathin leather, ultra stretch leather Culturing food has a long history 99% less USE OF LAND 96% less USE OF WATER Source: Tuomisto et al, Environmental Science & Technology (July 2011) 96% less GREENHOUSE GASES cultured agriculture cultured agriculture cultured agriculture cultured agriculture Significant resource advantages at scale 45% less USE OF ENERGY Early concept product: “Steak Chips” o No harm to animals or environment o Pure nutrition: high protein + vitamins – fat o Delicious flavor o Highest quality ingredients o Transparent production How do we grow cultured steak chips? 1 ISOLATE AND GROW CELLS 2 MULTIPLY CELLS 6 5 COOK IN DEHYDRATOR ENJOY! 3 ADD PECTIN FOR STRUCTURE 4 ADD SEASONING AND CALCIUM Our “steak chip” concept product was tasted by over 40 delighted participants at Google’s SolveForX event in 2013, and has since been enjoyed by hundreds of others. STRICTLY CONFIDENTIAL 15-04-19 | 17 Steak chip tastings Peter Thiel Sergey Brin Marc Andreessen Peter Diamandis & Jack Hidary Modern Meadow in numbers 20 10 $15M FULL TIME PROFESSIONALS PATENTS FILED CAPITAL RAISED 8 PhDs novel, scalable approach to growing large volumes of cells and tissues from top-tier Investors and grants tissue engineering cell engineering biochemistry chemical engineering bioengineering biophysics 10,000 chemistry SQUARE FEET design and business world-class cell biology R&D labs World class multi-disciplinary team R&D Lab & HQ (10,000 ft2) in Brooklyn Thank You Andras Forgacs CEO & Co-founder [email protected] With support from: