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Draft global e-learning module for food chemical risk assessment On-line course: Training program on Food Chemical Risk Assessment for developing country food safety regulators and the food Industry 27 March 2016 Table of content Filename Title/Content Type 0_01a Welcome 0_01b Introduction Text.docx 1_01a Food Chemical Risk Assessment 1_01b General concept Welcome Introduction Chapter 1: General Concepts on Food Chemical Risk Assessment Chapter 1.1: Introduction to General Concepts of Food Chemical Risk Assessment Chapter 1.2: Introduction to Toxicity and Toxicology Chapter 1.3: General Concepts on Food, Nutrition and Food Safety Chapter 1.4 : Unwanted Chemical Substances Chapter 1.5 :Food Production and Supply Chain Chapter 1.6 : Examples & case studies Chapter 2: Food chemicals – their toxicity Chapter 2.1 (a-c): Food chemicals – their toxicity Chapter 2.1 a: Introduction to Absorption, Distribution, Metabolism, and Excretion (ADME) Chapter 2.1 b: Introduction to Toxicokinetics and Toxicoynamics Chapter 2.1 c: Experimental data acquisition Introduction to the observed toxic effects Case about structure-activity relationships How to find the cramer class using ToxTree – exercise PPT DOC DOC Pages/ Slides 10 2 48 PPT 9 PPT PPT 18 9 PPT PPT PPT DOC PPT PPT 13 20 18 17 3 30 PPT 30 PPT PPT 18 13 DOC 7 Introduction to the observed toxic effects DNA as target – the mycotoxin aflatoxin B1 as an example Acrylamide Deriving an ADI from dose response in a pivotal study (real case)” Chapter 3.1 Regulatory framework Chapter 4: How much of it? Chapter 4.1 How much of it? PPT 4 PPT PPT 13 4 PPT DOC PPT 22 23 49 Exercise 4.2: Exposure assessment of a pesticide’s residues Exercise 4.3: Exposure assessment of a contaminant Acrylamide Chapter 5.1: Principles of Risk Analysis1 of Chemicals PPT 3 PPT 2 PPT 16 Chapter 5.2 Preliminary Risk Managament – Setting the goal Chapter 5.3: Principles of Risk Assessment of Chemicals Chapter 6.1: Specific aspects – Flavouring substances Food Contact Materials Chemicals being present not only in food Applications and Safety of Nanomaterials Used in Food PPT 22 PPT 20 PPT PPT PPT DOC 3 21 1_02 Toxicity and Toxicology 1_03 Food Nutrition Food Safety 1_04 Unwanted Substances 1_05 Food chain 1_06 Examples 2_01 Food chemicals Toxicity Text 2_01 Food Chemicals Toxicity 2_01a ADME 2_01b Toxicokinetics 2_01c Experimental data 2_02a Structure-activity relationship 2_02b Toxtree Cramer Class QSAR 2_03a Example aflatoxin 2_03b Acrylamide - Case study 2_04 Excercise ADI BHA 3_01 Regulatory framework 4_01a Exposure Assessment Text 4_01b Exposure Assessment Presentation 4_02 Exposure Assessment Exercise 4_03 Exposure Assessment Exercise Acrylamide 5_01 Formalizing the process-Risk Analysis 5_02 Formalizing the processPreliminary risk management 5_03 Formalizing the process-Risk assessment 6_01 Flavouring substances 6_02 Food Contact Materials 6_03 Non-food chemicals 6_04a Nanotechnology Text 6 Filename Title/Content Type 6_04b Nanotechnology Presentation 6_05a Novel Foods Text 6_05b Novel Foods Presentation 6_06a GMO Food Text Current Approach to the Safety Assessment of Foods Produced using Nanotechnology Chapter 6.2: Novel Foods Chapter 6.2: Regulation of novel foods Chapter 6.3a: Risk Assessment of Genetically Modified (GM) Food Chapter 6.3b: Current Approach to the Safety Assessment of GM Foods New Plant Breeding Technologies (NPBTs) Current Approach to the Safety Assessment of New Plant Breeding Techniques Wrapping up PPT Pages/ Slides 18 DOC PPT DOC 6 34 23 PPT 87 DOC PPT 25 20 PPT 7 6_06b GMO Food Presentation 6_07a New Plant Breeding Text 6_07b New Plant Breeding.pptx 7_01 Wrapping up Text documents: 157 pages Presentations: 540 slides