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ENDOCRINE SYSTEM Chapter 13 BASIC OVERVIEW: Endocrine vs. Exocrine Paracrine – nearby cells Prostaglandins Autocrine – affect itself Function: Help Control Homeostasis Slower than Nervous System Negative Feedback Hormones – Chemical Messengers Released into blood Only affect target cells Specific proteins in membrane PITUITARY GLAND Anterior Pituitary Controlled by Hypothalamus Hormones (releasing hormones) Hypophoseal Portal Veins Growth Hormone, Prolactin, Thyroid Stimulating Hormone, Adrenocorticotropic Hormone Gonadotropins: Leutinizing Hormone, Follicle Stimulating Hormone Posterior Pituitary Neurosecretory Cells of Hypothalamus Anti-diuretic Hormone (vasopressin) – H2O conservation Oxytocin – Uterus contraction (labor) OTHER ENDOCRINE GLANDS Thyroid Parathyroid Metabolism (BMR) Thyroxine + Triiodothryonine Calcitonin Posterior side PTH – bone resorption Adrenal Top of the kidneys Medulla Adrenaline (epinephrine) + Noradrenaline (norepinephrine) Fight or flight Cortex Aldosterone + Cortisol OTHER ENDOCRINE GLANDS Pancreas: glucose glycogen Islets of Langherans Beta Cells Insulin lower blood sugar Alpha cells glucagon increase blood sugar Delta Cells Somatostatin Pineal Gland Thymus Immunity Melatonin + circadian rythms Shrinks after childhood Testes, ovaries + placenta Sex hormones – secondary sex characteristics Pregnancy test - hcg