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RFA APPLICATION FORM 2015 REQUEST FOR APPLICATION (RFA): ENABLING DRUG SCREENING FOR ATAXIA TELANGIECTASIA Please check: PHASE ONE: Identification of Cellular Phenotypes and Target Proteins PHASE TWO: Assay Development for Screening Principal Investigator responsible for project Name: Institution: Address: Telephone: Email: Total funds requested for grant: Proposed grant period (one or two years): Institution's grants administrative officer Name: Title: Address: Telephone: Email: A-T CHILDREN’S PROJECT 5300 W. Hillsboro Blvd., Suite 105 • Coconut Creek, Florida 33073 Phone: (954) 481-6611 • www.atcp.org [email protected] 1 RFA APPLICATION FORM 2015 Institution's financial officer responsible for reports of expenditures and proposed grant funds Name: Title: Address: Telephone: Email: Grant payment checks Payable to: Mail to: Name: Title: Address: Institution and/or performance sites where research will be conducted Name: Address: Telephone: Employer Identification Number (EIN): A-T CHILDREN’S PROJECT 5300 W. Hillsboro Blvd., Suite 105 • Coconut Creek, Florida 33073 Phone: (954) 481-6611 • www.atcp.org [email protected] 2 RFA APPLICATION FORM 2015 Abstract of project – one page limit Describe briefly and clearly the nature, objectives, methods and significance to A-T of the proposed research project. Summary for lay persons – 200 word limit Rewrite the abstract in abbreviated form and in terms suitable for presentation to lay persons (200 word limit). Note that this summary should clearly explain the proposed work to nonscientists, but will not necessarily be presented to individuals with any emotional connection to A-T. Therefore, there is no need to interject hoped for but unrealistic long-term results or references to "potential therapies" in an attempt to "sell" the grant. BODY OF PROPOSAL - 10 page limit (not including references or budget ) Overall objectives: Hypothesis and specific aims: Background (previous work by other investigators and applicant): Rationale for current proposal: Methods and procedures: Anticipated problems and limitations: Data analysis: References Budget Detailed budget Budget justification Other financial support of principal and co-investigators Description of scientific environment A-T CHILDREN’S PROJECT 5300 W. Hillsboro Blvd., Suite 105 • Coconut Creek, Florida 33073 Phone: (954) 481-6611 • www.atcp.org [email protected] 3 RFA APPLICATION FORM 2015 Names, titles, telephone numbers and e-mails of co-investigators Attachments Curriculum Vitae for investigator and co-investigators (include recent, relevant publications). NIH style Bio sketches are acceptable. Letters of agreement from co-investigators If human subjects will be used in the proposed research, include copies of IRB approval (if already obtained), consent forms and statement of compliance with the NIH Office of Extramural Research (OER) guidance for research involving human subjects. Please note that for grant proposals requiring Institutional Review Board (IRB) approval, funding will be dependent upon and commence after IRB approval of the study protocol. If animals will be used in the proposed research, provide a statement of compliance with American Veterinary Medicine Association and NIH guidelines. A-T CHILDREN’S PROJECT 5300 W. Hillsboro Blvd., Suite 105 • Coconut Creek, Florida 33073 Phone: (954) 481-6611 • www.atcp.org [email protected] 4