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長庚大學醫學院生物醫學研究所 博士班畢業演講公告 演講者:祁 祥 正 博士候選人 現職:長庚大學生物醫學研究所生化暨細胞分子生物學組 博士班 題目:TRAIL受甲狀腺素及甲狀腺素接受體調控之研究及其於肝癌細 胞轉移的相關性 Thyroid hormone receptors promote metastasis of human hepatoma cells via regulation of TRAIL 時間:101 年 5 月 24 日上午 9:30 地點:第一醫學大樓八樓生醫所辦公室 主持人:林光輝 教授 ※※※歡迎踴躍參加※※※ Curriculum Vitae Name: 祁祥正 Hsiang-Cheng Chi Date & Place of Birth: Apr, 17, 1982, Taiwan Citizenship: Taiwan Title, Affiliation and Office Address PhD candidate Graduate Institute of Biomedical sciences & Department of Biochemistry and Molecular Biology Chang Gung University 259 Wen-Hwa 1st Road, Taoyuan 333, Taiwan Phone: (886)-3-2118800 ex 5177 Fax: (886)-3-2118263 E-mail: [email protected] Eduction 2006 - present : PhD PhD student, Chang Gung University, Taoyuan, Taiwan 2004 - 2006 : MS Master, Graduate Institute of Life science, National Central University, Jhongli 320, Taiwan 2000- 2004 : BS Nutrition, Chung Shan medical University, Taichung, Taiwan Academic and professional appointments 2008 - present : Assistant Chang Gung hospital, Chiayi, Taiwan Research Interests Tumor biology, basic and translational research Publications 1. Chang, J-H., Lin, K-H., Shih, C-H., Chang, Y-J., Chi,C-H., and Chen, S-L. Myogenic bHLH proteins regulate the expression of PPAR-gamma coactivator -1α Endocrinology. 147(6):3093-3106. 2006 2. Chen-Hsin Liao, Shih-Chi Yeh, Ya-Hui Huang, Ruey-Nan Chen, Ming-Ming Tsai, Wei-Jan Chen, Hsiang-Cheng Chi, Pei-Ju Tai, Chia-Jung Liao, Sheng-Ming Wu, Wan-Li Cheng , Li-Mei Pai, K-H Lin (corresponding author) Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion. Endocrine-Related Cancer 17:99-111, 2010 3. C-H Liao, C-T Yeh, Y-H Huang, S-M Wu, H-C Chi, M-M Tsai, C-Y Tsai, C-J Liao, Y-H Tseng, Y-H Lin, C-Y Chen , I-H Chung, W-L Cheng, W-J Chen, *K-H Lin. Dickkopf 4 positively regulated by the thyroid hormone receptor suppresses cell invasion in human hepatoma cells. Hepatology 2011 Oct 12. doi: 10.1002/hep.24740. 4. C-Y Chen, L-M Chi, H-C Chi, M-M Tsai, C-Y Tsai, Y-H Tseng, Y-H Lin, W-J Chen, *K-H Lin Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)-based quantitative proteomics study of a thyroid hormone-regulated secretome in human hepatoma cells. Mol Cell Proteomics 5. Ming-Ming Tsai, Paul Y. Lin, Wan-Li Cheng, Chung-Ying Tsai, Hsiang-Cheng Chi, Cheng-Yi Chen, Yi-Hsin Tseng, Yi-Fen Cheng, Chi-De Chen, Ying Liang, Chia-Jung Liao, Sheng-Ming Wu, Yang Hsiang Lin, I-Hsiao Chung, Chia-Siu Wang, and *K-H Lin. Overexpression of ADP-Ribosylation factor 1 in Human Gastric Carcinoma and its Clinicopathological Significance Cancer Science 6. Wan-Li Cheng, Ming-Ming Tsai, Chung-Ying Tsai, Ya-Hui Huang, Cheng-Yi Chen, Hsiang-Cheng Chi, Yi-Hsin Tseng, Im-Wai Chao, Wei-Chi Lin, Sheng-Ming Wu, Ying Liang4, Chia- Jung Liao, Yang-Hsiang Lin, I-Hsiao Chung, Wei-Jan Chen, Paul Y. Lin, and Chia-Siu Wang, *K-H Lin. Glyoxalase-I is a novel prognosis factor associated with gastric cancer progression. PLoS ONE 7. H-C Chi, S-L Chen2, C-J Liao, C-H Liao, M-M Tsai, Y-H Lin, Y-H Huang, C-T Yeh, S-M Wu, Y-H Tseng, C-Y Chen, C-Y Tsai,I-H Chung, W-J Chen6 and *K-H Lin. A novel function of thyroid hormone receptors in promoting metastasis of human hepatoma cells via regulation of TRAIL. Cell Death and Differentiation (In Press) Conference papers 1. Hsiang-cheng Chi ,Chia-Siu Wang, Kwang-Huei Lin. Expression and regulation of aldose reductase by thyroid hormone receptor in human hapatoma cell lines . (The Endocrine Society 90th Annual Meeting San Francisco, California , 2008 Jan. 15-18))