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CURRICULUM VITAE Personal Data: Name: Khadijeh Jamialahmadi Sex: Female Date of Birth: 1974 Place of Birth: Torbat Jam/Iran Nationality: Iranian Marital status: Married Present position: Assistant Professor in Pharmaceutical Biotechnology, Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Phone: +98-511-8002293 Fax: +98-511-8002960 E. mail: [email protected] Mailing address: Department of Modern Sciences and Technologies, Faculty of Medicine, Pardis Campus, Azadi Square, Mashhad-Iran. Phone: +98-511-8002293 Fax: +98-511-8002960 E. mail: [email protected] Educational Background: - 2003-2008: Ph.D. degree in Pharmaceutical Biotechnology, Tehran University of Medical Sciences, Tehran, Iran. - 1994-2000: Pharm degree, Mashhad University of Medical Sciences, Mashhad, Iran. Seminar: - Production and Optimization of N-Acetyl-D-glucosamine by Chitinase from the Isolated Microorganisms. 28/12/2008, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. - Investigation of Polymer Mixtures for Zero-order Release of Propranolol Hydrochloride from HPMC Matrices. 20/6/2000, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Research Experiment: - Gene cloning and Protein expression in E.coli - Construction and Screening of DNA libraries - Protein purification - Mutation Detection Analysis (DNA and RNA Extraction, PCR, SSCP) - RFLP - Immunohistochemistry Technique - Enrichment and isolation of novel single microorganisms from environments - HPLC analysis of Saccharides Professional Interests: - Cancer, Gene cloning, Glycobiology, Purification, characterization and application of biocatalysts, Protein purification Publications: - Expression of Membranous Epidermal Growth Factor Receptor in Colorectal Adenocarcinoma and Itۥs Correlation with Clinicopathological Features. G. Mohammadi, K. Jamialahmadi, S. Lary, K. Ghaffarzadegan. Pakistan Journal of Biological Sciences, 2011, Submitted - Enzymatic Production of N-Acetyl-D-Glucosamine from Chitin Using Crude Enzyme Preparation of Aeromonas sp. PTCC1691. K. Jamialahmadi, J. Behravan, M. Fathi Najafi, M. Tabatabaei Yazdi , A.R. Shahverdi, M.A.Faramarzi. Biotechnology, 2011, Submitted افزایش سطح سرمی فعالیت آنزیم آلکالین فسفاتاز در معتادین مصرف سیما، مجله ي علوم پزشکی دانشگاه آزاد اسالمی مشهد،کننده ی کریستال ، خدیجه جامی االحمدي، محمود عرفانیان احمدپور، محمد محمدي،افشارنژاد )پژوهشی- (علمی.85-90 صفحه،)18( پیاپی2 شماره، سال پنجم، 1388 تابستان - Investigation of Factors Affecting on the Activity and Stability of chitinase from Aeromonas sp. PTCC1691. K. Jami al Ahmadi, J. Behravan, M. Fathi Najafi, M. Tabatabaei yazdi. Proceedings of the 2010 International Conference on Biotechnology and Food Science; 2010, pp. 129-133. - Clinicopathological significance of E-cadherin, -catenin, p53 expression in gastric adenocarcinoma. MR. Zali, O. Moaven, H. Asadzadeh Aghdaee, K. Ghaffarzadegan, K. Jami Ahmadi, M. Farzadnia, A. Arabi, MR. Abbaszadegan. Journal of Research in Medical Sciences; 14(4): 239-247, 2009. (ISI) - Optimization of cultural conditions for production of chitinase by a soil isolate of Massilia timonae. M. A. Faramarzi, M. Fazeli, M. Tabatabaei yazdi, S. Adrangi, K. Jami al Ahmadi, N. Tasharrofi, F. Aziz Mohseni. Biotechnology; 8(1): 93-99, 2009. (ISI) - Optimization of medium and cultivation conditions for chitinase production by the newly isolated: Aeromonas sp. K. Jami al Ahmadi, M. Tabatabaei yazdi, M. Fathi Najafi, AR. Shahverdi, M. A. Faramarzi, G. Zarrini, J. Behravan. Biotechnology; 7(2): 266-272, 2008. (ISI) - Isolation and characterization of a chitionolytic enzyme producing microorganism, Paenibacillus chitinolyticus JK2 from Iran. K. Jami al Ahmadi, M. Tabatabaei yazdi, M. Fathi Najafi, A.R. Shahverdi, M.A. Faramarzi, Gh. Zarrini and J. Behravan. Research Journal of Microbiology; 3(6): 395-404, 2008. - Isolation and characterization of a chitionolytic enzyme producing microorganism, Paenibacillus chitinolyticus JK2 from Iran. K. Jami al Ahmadi, M. Tabatabaei yazdi, M. Fathi Najafi, AR. Shahverdi, M. A. Faramarzi, Gh. Zarrini and J. Behravan. Proceedings of the 8th International Conference of the European Chitin Society. 153-158, 2007. - Correlation of nuclear p53 immunoreaction with the histopathologic features in Gastric carcinoma. K. Ghaffarzadegan, MR. Zali, K. Jami Ahmadi, H. Asadzadeh, MR. Abbaszadegan. Archives of Iranian Medicine; 7(4): 279-283, 2004. (ISI) - Prevalence of Human Papilloma Virus type16, 18 and p53 mutant protein expression in Esophageal Squamous Cell Carcinomas. Abbaszadegan MR, Omidi AA, Niyazi AA, Zoheidi MR, Gholamin M, Jami Ahmadi Kh, Ghaffarzadegan K. Iranian Journal of Basic Medical Sciences; 1(6): 38-42, 2003. - The expression of E-cadherin in Gastric carcinomas: a clinicopathological study. Abbaszadegan MR, Jami Ahmadi K, Asadzadeh H, Zali MR, Ghaffarzadegan K. Gut; 52 (Suppl VI) A146; 2003. - Mutational analysis of APC gene, immunoreactivity of p53 and E-Cadherin protein in Gastric Adenocarcinoma. Abbaszadegan MR, Asadzadeh H, Pazouki N, Ghaffarzadegan K, Jami Ahmadi K, Houshmand M, Zali MR. The American Journal of Human Genetics. Vol 69 (Suppl), No 4, 2001. Presentation: - Correlation of membranous epidermal growth factor receptor immunoreactivity with the clinicopathological features in colorectal adenocarcinoma. K. Jamialahmadi, M. Mohammadi, S. Lary, K. Ghaffarzadegan. The 1st International Student Congress on Cell and Molecular Medicine (ISCCMM 2011). Shiraz, Iran, 2011. - Selective production of 2-acetamido-2-deoxy-D-glucose by enzymatic hydrolysis of chitin. K. Jamialahmadi, J. Behravan, M. Fathi Najafi, M. Tabatabaei yazdi, AR. Shahverdi, MA. Faramarzi. 11 th Iranian Congress of Biochemistry. Qazvin, Iran, 2011. - Bioethical Issues in Biotechnology Researches. K. Jamialahmadi, 12th Iranian Pharmaceutical Science Congress (IPSC2010). Zanjan, Iran, 2010. - Production of chitinase by a newly isolated Cellulomonas sp. K. Jami al Ahmadi, M. Tabatabaei, J. Behravan, M. Fathi Najafi , M. Faramarzi, A. Shahverdi, G. Zarrini. 3rd International PhD student symposium "Horizons in Molecular Biology". Gottingen, Germany, 2006. - Production of chitinase as a potential antifungal agent: Isolation and identification of chitinolytic microorganisms from the ecosystems of Iran. K. Jami al Ahmadi, M. Tabatabaei, J. Behravan, M. Fathi Najafi, M. Faramarzi, A. Shahverdi, G.Zarrini. 10th Iranian Pharmaceutical Sciences Conference. Tehran, Iran, 2006. - Characterization and optimization of chitinase production from a novel chitinolytic bacterial isolate (JK1). J. Behravan, K. Jami al Ahmadi, M. Tabatabaei and M. Fathi Najafi. XXIII rd International Carbohydrate symposium. Whistler, Canada, 2006. - Enrichment of chitinolytic microorganisms: Characterization and Optimization of Chitinase Production from a Novel Chitinolytic Bacterial Isolate (JK1). K. Jami al Ahmadi, M. Tabatabaei, J. Behravan, M. Fathi Najafi, M.Faramarzi, A. Shahverdi, G. Zarrini. 7th Asia-Pasific Chitin and Chitosan Symposium. Busan, Korea, 2006. - Correlation of nuclear p53 immunoreactivity with the histopathologic features in Gastric carcinoma. Ghaffarzadegan K., Abbaszadegan MR., Jami Ahmadi K. 11th United European Gastroenterology Week, Madrid, Spain, 2003. - Mitochondrial DNA alterations in Gastric cancer. Heidari N., Abbaszadegan MR., Pazouki N., Jami Ahmadi K., Shafa Shariat Panahi M., Rashedi I., Houshmand M. The First Scientific Meeting of Asian Society for Mitochondrial Research and Medicine. Seoul, Korea, 2003. - The expression of E-Cadherin in Gastric carcinoma: a clinicopathological study. Abbaszadegan MR., Jami Ahmadi K., Asadzadeh H., Zali MR., Ghaffarzadegan K. From Bed to Bench in Gastroenterology, Tehran, Iran, 2002. - E-Cadherin germline mutations in familial Gastric cancer. Abbaszadegan MR., Jami Ahmadi K., Raziee H. Second Iranian Congress of Genetic Disorders and Disabilities, Tehran, Iran, 2002. - Correlation of nuclear p53 immunoreaction with the histopathologic features in Gastric carcinoma. Ghaffarzadegan K., Abbaszadegan MR., Jami Ahmadi K., Asadzadeh H., Zali MR. Iranian Annual Pathology Congress, Tehran, Iran, 2002. - Correlation of E-Cadherin expression with the histopathologic features in Gastric carcinoma. Jami Ahmadi K., Ghaffarzadegan K., Abbaszadegan MR. Human Genome Diversity in Islamic Countries, Tehran, Iran, 2002. - Molecular study of the Adenomatous Polyposis Coli (APC) gene mutations in Gastric cancer among the Iranian population by PCR-SSCP and LOH-RFLP. Pazouki N., Jami Ahmadi K. International Student Congress of Medical Sciences, Shiraz, Iran, 2001. - Immunohistochemical detection for the p53 mutant protein and E-Cadherin protein in Gastric cancer among the Iranian population. Ghaffarzadegan K., Jami Ahmadi K., Zali MR., Asadzadeh H., Pazouki N., Abbaszadegan MR. 6th Iranian Congress on Biochemistry, Tehran, Iran, 2001. - Molecular study of the Adenomatous Polyposis Coli (APC) gene mutations in Adenocarcinoma of Gastric cancer among the Iranian population by PCR-SSCP. Abbaszadegan MR., Jami Ahmadi K., Pazouki N. The Second National Biotechnology Congress, Karaj, Iran, 2001. - Expression patterns of E-Cadherin in Gastric cancer among the Iranian population. Abbaszadegan MR., Jami Ahmadi K., Ghaffarzadegan K., Pazouki N. First International Iranian Congress on Cancer, Mashhad, Iran, 2001. - Mutational analysis of APC gene, immunoreactivity of p53 in Gastric Adenocarcinoma. Abbaszadegan MR., Pazouki N., Jami Ahmadi K., Ghaffarzadegan K. First International Iranian Congress on Cancer, Mashhad, Iran, 2001. - Mutation detection in Gastric cancer. Abbaszadegan MR, Pazouki N, Jami Ahmadi K., Ghaffarzadegan K, Zali MR, Asadzadeh H. The 1th Iranian Congress of Cancer Research, Uremia, Iran, 2001. - Investigation of polymer mixtures for zero-order release of Propranolol Hydrochloride from HPMC matrices. Jami al Ahmadi K. The 6th country Pharmacy Student Seminar, Ahvaz, Iran, 1999. Sequence Submissions - Jami al Ahmadi, K., Behravan, J., Tabatabaei Yazdi, M., Fathi Najafi, M., Zarrini,G., Faramarzi, M.A. and Shahverdi, A. DQ985606, Aeromonas sp. JK1 16S ribosomal RNA gene, partial sequence (2006). - Jami al Ahmadi, K., Fathi Najafi, M., Behravan, J., Tabatabaei Yazdi, M., Zarrini, G., Faramarzi, M.A. and Shahverdi, A. EF011984, Paenibacillus chitinolyticus strain JK2 16S ribosomal RNA gene, partial sequence (2006). - Jami al Ahmadi, K., Tabatabaei Yazdi, M., Behravan, J. and Fathi Najafi, M. EF157938, Cellulomonas sp. JK3 16S ribosomal RNA gene, partial sequence (2007). Microorganism Submissions - Persian Type Culture Collection, Tehran, Iran: PTCC 1691 Aeromonas sp. Research Projects: - A survey on knowledge and attitude of faculty members and postgraduate students of basic sciences departments of faculty of medicine regarding to bioethical issues, Mashhad University of Medical Sciences, 2011. (Investigator). - Evaluation of association between rs16139 and rs16147 polymorphism of NeuropeptideY (NPY) gene and Coronary Artery Disease based on angiography in candidates of angiography and angioplasty, Mashhad University of Medical Sciences, 2010. (Investigator). - The effects of N-acetylglucosamine on spatial learning in the Morris water maze task in rats, Mashhad University of Medical Sciences, 2010. (Investigator). - Preparation and characterization of liposomes containing N-acetylglucosamine and evaluation the moisturizing effect of these nanoliposomes, Mashhad University of Medical Sciences, 2010. (Investigator). - Production, Purification and Characterization of Chitinase from Aeromonas PTCC 1691, Mashhad University of Medical Sciences, 2009. (Investigator). - Evaluation of antifungal effects of chitinolytic microorganism Aeromonas sp. JK1. Mashhad University of Medical Sciences, 2007. (Investigator). - Production of chitinase and its optimization from a novel chitinolytic bacterial isolate (JK1) Tehran University of Medical Sciences, 2006. (Co-investigator). - Identification of four chitinolytic microorganisms isolates by 16srRNA sequencing technique. Mashhad University of Medical Sciences, 2006. (Co-investigator). - Mutational analysis of Gastric carcinoma in Iran. Research Center of Gastroenterology and Liver transplantation, Shahid Beheshti University of Medical Sciences, 2000. (Co-investigator) - Study of E-Cadherin Germline Mutations in Familial Gastric Cancer. Research Center of Gastroenterology and Liver transplantation, Shahid Beheshti University of Medical Sciences, 2001. (Co-investigator) - Detection of Human Papiloma Virus DNA by the PCR in oral SCC and dysplasia and its relationship with p53 tumor suppressor expression. Mashhad University of Medical Sciences, 2001. (Co-investigator). Workshops: - Polymerase Chain Reaction (PCR) and RT-PCR, Buali Research Institute, Mashhad, Iran, 2010. - Genome Wide Association Studies (GWAS), Buali Research Institute, Mashhad, Iran, 2010. - Protein purification, Center of Protein engineering (CIP), Faculty of Sciences, University of Liege, Belgium, 2008. - Scientific writing, Tehran University of Medical Sciences, Tehran, Iran, 2005. - Application of voltammetry and pollarography techniques in food and pharmaceutical industries. Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, 2004. - The 3rd training course of molecular detection of cancer. Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, 2004. - Bioinformatics. Pasteur Institute of Iran, Tehran, Iran, 2004. - The 1st International Training Course on Production and Application of Biological Enzyme Preparation in Industry. TCDC, Boading, China, 2004. - Scientific writing, Institute of Biophysics and Biochemistry (IBB), Tehran, Iran, 2003. - Gene transfer to plasmid and its analysis. Mashhad University of Medical Sciences, Mashhad, Iran, 2003.