Download Powerpoint - Blood Journal

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

page
1
page
2
page
3
page
4
page
5
page
6
page
7
page
8
Document related concepts
no text concepts found
Transcript 
Surface antigen phenotypes of hematopoietic stem cells
from embryos and murine embryonic stem cells
by Shannon L. McKinney-Freeman, Olaia Naveiras, Frank Yates, Sabine Loewer,
Marsha Philitas, Matthew Curran, Peter J. Park, and George Q. Daley
Blood
Volume 114(2):268-278
July 9, 2009
©2009 by American Society of Hematology
E11.5 AGM-derived repopulating cells do not express CD150 or CD48.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
E12.5 Placenta-derived repopulating cells do not express CD150 or CD48.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
CD150 and CD48 expressing cells are not detectable in E9 YS. Representative analysis of E9 YSderived cells analyzed by flow cytometry for the cell surface expression of c-Kit, CD34, CD41,
CD150, and CD48.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
EPOCH cells are phenotypically heterogeneous.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
ESC-HSC are CD41highCD34− and heterogeneous with respect to CD45 cell-surface expression.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
ESC-HSC are CD150+ and heterogeneous with respect to CD48 cell-surface expression.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
Cell surface phenotype of embryonic and ESC-derived HSCs. Our data further defines the cellsurface phenotype of both murine ESC-HSCs and in vivo HSCs during ontogeny, especially with
regard to the expression of the SLAM family of cell surface molecules.
Shannon L. McKinney-Freeman et al. Blood 2009;114:268278
©2009 by American Society of Hematology
Related documents