Download Richard P Harvey, PhD FAA

Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Richard P Harvey, PhD FAA
The Victor Chang Cardiac Research Institute
Lowy Packer Building
405 Liverpool Street
Darlinghurst NSW 2010
Australia
Nationality:
Telephone:
Facsimile:
Email:
Australian
+61 2 9295 8620 (work – Direct)
+61 2 9295 8601
[email protected]
QUALIFICATIONS
1982
1977
1976
PhD Molecular Biology; “The Isolation and Characterisation of Chicken Histone
Genes”; Department of Biochemistry, University of Adelaide, Adelaide Australia.
Advisor: Dr Julian RE Wells
BSc (Hons) (1ST class), Molecular Biology, University of Adelaide, Adelaide
Australia
BSc Biochemistry, University of Adelaide, Adelaide Australia
PRESENT POSTS




Deputy Director, Victor Chang Research Institute (since August 2003)
Head of the Developmental and Stem Cell Biology Division, Victor Chang Cardiac Research
Institute
Sir Peter Finley Professor of Heart Research, Victor Chang Cardiac Research and the Faculty
of Medicine, University of New South Wales, Australia (since February 1998)
Member, Scientific Leadership Group, Australian Research Counsel Special Research
Initiative in Stem Cell Science (Stem Cells Australia)
PROFESSIONAL EXPERIENCE
1992-1998
1991-1995
1988-1990
1986-1987
1985-1986
1983-1984
1982-1983
Senior Research Fellow and Faculty Member, The Walter and Eliza Hall Institute
of Medical Research, Melbourne, Australia; Associate of the University of
Melbourne in the Department of Medical Biology
Australian Research Council (ARC) Research Fellow, The Walter and Eliza Hall
Institute of Medical Research, Melbourne, Australia
Australian Research Council (ARC) Queen Elizabeth II Postdoctoral Fellow, The
Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
National Institutes of Health (USA) Fogarty International Postdoctoral Fellow,
Harvard University, Cambridge, Massachusetts, USA
Postdoctoral Fellow, Harvard University, Cambridge, Massachusetts, USA
Research Scientist, Transgene (Biotechnology), Strasbourg, France
Postdoctoral Fellow, University of Adelaide, Adelaide, Australia
Page 1 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
HONOURS AND AWARDS
2010
2009
2009-2013
2008
2007
2007
2006
2005
2004
2001
1998
1991-1995
1988-1990
1986-1987
1982
Lemberg Medal and Oration, Australian Society for Biochemistry and Molecular
Biology (lecture at OzBio 2010; profile published in Australian Scientist)
President’s Medal and Oration, Australian and New Zealand Society of Cell and
Developmental Biology (lecture at Combio 2009)
NHMRC Australia Fellowship
Associate Member of European Molecular Biology Organisation (EMBO)
Evelyn Hall Award for Excellence in Research, National Heart Foundation of
Australia
Fellow of the Australian Academy of Science (Inducted May 3rd, 2007)
“Directeur of Recherche” (Visiting Professorship at University Pasteur, Paris;
Director Margaret Buckingham; administered by CNRS)
Julian Wells Medal and Oration; Lorne Genome Meeting 2005, Phillip Island,
Australia (Interview published in Life Scientists, January 2005)
RT Hall Prize, Senior Scientific Award of the Cardiac Society of Australia & New
Zealand (CSANZ)
Hazel Coke Research Excellence Award, National Heart Foundation of Australia
Sir Peter Finley Endowed Professorship, University of New South Wales/Victor
Chang Cardiac Research Institute
Australian Research Council (ARC) Research Fellowship, The Walter and Eliza
Hall Institute of Medical Research, Melbourne, Australia
Australian Research Council (ARC) Queen Elizabeth II Postdoctoral Fellow, The
Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
National Institutes of Health (USA) Fogarty International Fellowship
Culross Prize for Scientific Research (PhD thesis)
GRANT SUPPORT
National Heart Foundation of Australia, Grant in Aid: Use of iPS cells to study the molecular
basis if hypoplastic left heart syndrome. 2012-2013. Total: $130,000. CI: R Harvey (VCCRI).
Australia-India Strategic Research Fund Grant (Indio-Australia Biotechnology Fund):
“Therapeutic approaches to augmentation of adult cardiac stem cells” 2012-2014. Total $400,000.
CIs: R Harvey (VCCRI), J. Dhawan/R Mishra (India).
UNSW Major Research Equipment & Infrastructure Scheme: “UV microscope to analyse
membrane protein crystals destined for X-ray analysis” 2011. Total $120,000. CIs B Martinac
(VCCRI), RM Graham (VCCRI), RP Harvey (VCCRI), D Stock (VCCRI).
UNSW Major Research Equipment and Infrastructure Scheme: “Fully equipped live cell
imaging and real time lineage tracking apparatus and accessories to upgrade existing Zeiss
confocal microscope” 2010. Total $142,000. CIs J Pimanda (UNSW), R Harvey (VCCRI), R
Ward (UNSW), L Khachigian (UNSW), R Lock (UNSW), R Nordon (UNSW), K McDonald
(UNSW), M Crossley (UNSW).
Rebecca Cooper Medical Research Foundation Research Grant: “Real time, single cell
lineage tracking of cardiac stem cell maintenance, activation and rejuvenation”. 2010. Total
$22,000. CI R Harvey; AIs: M Xaymardan, R Nordon (UNSW)
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Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Australian Research Council Strategic Initiative in Stem Cell Science: “Stem Cells
Australia”. 2011-2018. Total: $21million, VCCRI: $2.1million; ID: SR110001002; CIs: M Pera,
T Kilpatrick, D Gardner, D Hilton, N Rosenthal, A Elefanty, E Stanley T Barberi, P Gray, M
Little, J Cooper-White, S Grimmond, E Wolvetang, L Nielsen, P Bartlett, C Wells, RP Harvey, R
Graham.
Cancer Institute NSW Equipment Grant, 2010, “An Influx Cell Sorter to upgrade the Garvan
Institute/St Vincent's research precinct flow cytometry facility” Total: $500,000, ID: N/A, CI: S
Tangye, CI: A Swarbick, CI: E Musgrove, CI: C Suter, CI: RP Harvey, CI: R Brink, CI: R Daly,
CI: J Pimanda, CI: A Kellher, CI: D Ma.
ARC LIEF, 2010, “Fluorescence microscopy with optical tweezers: imaging cellular responses”,
Total: $600,000, ID: LE110100092, CI: P Gunning, CI: K Gaus, PI: W Weninger, PI: L
Khachigian, PI: J Phillips, PI: S Russell, PI: G Grau, PI: E Hardeman, PI: J Gooding, PI: N King,
PI: T Grewal, PI: L Soon, PI: J Coorssen, PI: G O'Neill, PI: D James, PI: M Kavallaris, PI: R
Harvey
Atlantic Philanthropies, Flagship Grant, 2010, “Genome-wide dissection of endothelial cell
specification, specialization and behaviour”, Total: $272,705.25, ID: 19131, CI: R Harvey, CI:
R.M Graham, CI: B Black, CI: D Fatkin, CI: S.R Coughlin.
New South Wales Cardiovascular Research Network, 2010, “Congenital and inherited heart
disease grant”, Total: $300,000, ID: N/A PI: Celermajer D, CIA: Winlaw D, CIB: Sholler D, CIC:
Fatkin D, CID: Harvey RP, CIE: Richmond J, CIF: Semsarian C, CIG: Puranik R, CIH: Kizana E,
CII: Sullivan DR
NHMRC Program Grant, 2010-2014, “Molecular mechanisms of cardiac function and disease”,
Total: $9.35 million, ID: 573732, CI: Graham RM, PI: Feneley M, PI: Fatkin D, PI: P
McDonald, PI: Harvey RP, PI: D Allan
ASCC Collaborative Stream 4, 2009-2011, “Adult stem cell program”, Total: $363,700, ID:
S4M1, CI: RP Harvey
ASCC Collaborative Stream 2, 2009-2011, “Reprogramming and induction of pluripotency”,
Total: $120,040, ID: S2M6, CI: RP Harvey
NHMRC Australia Fellowship, 2009-2013, “Application of systems biology to cardiac
development and disease”, Total: $4 million, ID: 573705, CI: Harvey RP
NHMRC Project Grant, 2009-2013, “Homeodomain NKx2-5 dependent negative feedback loop
important in heart development and congenital heart disease”, Total: $1.25 million, ID: 573703,
CIA: Harvey RP, CIB: Dunwoodie S
Australian Research Council Discovery Grant, 2009-2011, “Gene regulatory networks in heart
development”, Total: $460,000, ID: DP0988507, CIA: Harvey RP, CIB: Wouters M, CIC/APD:
Bouveret R
National Heart Foundation Grant in aid, 2009-2010, “Mechanisms and modifiers of congenital
heart disease”, Total: $130,000, ID: G08S3718, CIA: Harvey RH, CIB: Prall O
Page 3 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
St Vincent’s Hospital Clinical Foundation, 2009, “Reprogramming of pluripotent cells from adult
cardiac stem cells In vitro without genetic modification”, Total: $100,000, ID: N/A, CIA: Harvey
RP
Australia India Strategic Research Fund (AISRF), July2009-June2011, “Endogenous adult
cardiac stem cells: Genome wide analysis of multipotency and differentiation in homeostasis and
regeneration”, Total: $400,000, ID: BF020084, CIA (Australia): Harvey RP, CIA (India):
Dhawan J
Australian Stem Cell Centre, 2008-2009, “Endogenous Cardiac Stem Cells”, Total: $512,945,
ID: PO82, CIA: Harvey RP
National Heart Foundation, 2007-2008, “Identifying common alleles underlying polygenic
congenital heart disease”, Total: $129,000, ID: G06S2575, CIA: Harvey RP, CIB: Kirk E, CIC:
Moran C
Sydney Heart Valve Bank, 2005-2006, $60,000, N/A, Winlaw D – CIA, Harvey RP – CIB
Johnson & Johnson Focused Giving Grant, 2005 – 2006, $417,437, ID: N/A, CI: Harvey RP,
PI: Prall O
National Institutes Of Health (USA) Exploratory/Development Award, 2005-2006,
“Comparative genetics of cardiac chamber formation”, Total: $265,206, ID: 1R21HD047858, CI
(USA): Yelon D, CI (Australia): Harvey RP, PI: Prall O
NHMRC Program Grant, 2005-2009, $7.725 Million, ID: 354400, CI: Graham RM, PI:
Feneley M, PI: Alan D, PI: Fatkin D, PI: Harvey RP
Australian Stem Cell Centre, 2004-2006, “Cardiac therapeutic focus”, Total: $1.7 Million, ID:
PO82, CI: Harvey RP, PI: Graham RM, PI: Feneley M, PI: Fatkin D
NHMRC, Project Grant [Forfeited under NHMRC Program Grant #354400],
2004-2006, “Role of homeobox gene Nkx2-5 in heart development and congenital disease”,
Total: $493,000, ID: 303706, CIA: Harvey RP, CIB: Schaft D, CIC: Prall O
Federal Government Innovation Access Conference Grant, 2003-2005, “International
Conference Grant – Society of Developmental Biologist Congress”, Total: $50,000, ID: N/A,
Harvey RP, Co-Convenors: Dunwoodie SL, Currie P
NHMRC Project Grant [Forfeited under NHMRC Program Grant #354400], 2003-2005,
“Role of the T-box transcription factors, Tbx5 and Tbx20, in cardiac development and congenital
heart disease”, Total: $470,000, ID: 256302, CIA: Harvey RP, CIB: Stennard F, CIC: Costa M
ARC Discovery Project Grant, 2003-2005, “Molecular mechanisms of stem cell self-renewal”,
Total: $251,261, ID: DPO346726, CIA: Harvey RP, CIB: Graham RM, CIC: Yeoh T
Pfizer Australia, 2003, “Role of the small muscle-specific protein Chisel (Csl) in muscle
adaptation and regeneration”, Total: $637,029, ID: N/A, CIA: Harvey RP
Page 4 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Muscular Dystrophy Association, 2002, “The role of P38 kinase in generation of muscle cells in
vitro”, Total: $27,441, ID: N/A, CIA: Harvey RP, CIB: Yeoh T
NHMRC Project Grant, 2002-2004, Genetic and molecular dissection of laterality in the
developing heart”, Total: $378,600, ID: 213402, CIA: Harvey RP, CIB: Biben C
ARC Discovery Project Grant, 2002-2004, “Control of transcription by the cardiac
homeodomain protein Nkx2-5”, Total: $232,641, ID: DPO21200, CIA: Harvey RP
NIH NIHLB (USA) Research Grant, 2002-2004, $936,308, ID: 1RO1HL, 68885-01, CIA:
Harvey RP, CIB: Kirk EPE, CIC: Buckley MF
RT Hall Trust, 2001-2003, “Mapping genes responsible for congenital heart disease”, Total:
$90,678, ID: N/A, CIA: Harvey RP
National Heart Foundation Grant in Aid, 2002-2003, “Mapping of modifier loci for patent
foramen ovale (PFO) and Atrial Septal dysmorphogenesis in mice“, Total: $73,760, ID:
G0050738, CIA: Harvey RP, CIB: Kirk EPE, CIC: Buckley MF
NHMRC Project Grant, 2000-2002, $332,919, ID: 109000, CIA: Graham RM, CIB: Harvey
RP, CIC: Vo K
National Heart Foundation Grant in Aid, 2000-2001, “Cardiac abnormalities due to mutation
of the regulatory gene Nkx2-5: genetic screening in humans and functional studies in mice”,
Total: $66,600, ID: G9950480, CIA: Harvey RP, CIB: Feneley M
NHMRC Project Grant, 2000-2002, “Role of homeobox gene Nkx2-5 in heart development and
congenital heart disease”, Total: $227,341, ID: 109002, CIA: Harvey RP
NHMRC Project Grant, 1999-2001, “Characterisation and functional analysis of a novel Nkx25 – regulated gene in cardiac and skeletal muscle”, Total: $257,797, ID: 990874, CIA: Harvey
RP, CIB: Palmer S
NHMRC Project Grant, 1999-2001, “The signalling antagonist mCer-1 and its role in
development of brain and mouse embrtyos”, Total: $382,200, ID: 990689, CIA: Harvey RP, CIB:
Biben C
Amrad Corp. Research Grant, 1998-1999, $245,580, ID: N/A, CIA: Harvey RP, CIB: Stanley
E
NIH NIA (USA) (RO3) Research Grant, 1998, $67,750, ID: PA-96-023, CIA: Harvey RP, CIB:
Rosenthal N
National Heart Foundation Grant in Aid, 1997-1998; $50,149, ID: G9644675, CIA: Harvey
RP
Human Frontiers Science Foundation Grant, 1995-1997, $168,184, ID: N/A, PI: Harvey RP,
PI: Olson E, PI: Schultz R
Page 5 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
National Heart Foundation Grant in Aid, 1995-1996, $45,750, ID: N/A, CIA: Harvey RP
National Heart Foundation Grant in Aid, 1993-1994, $60,000, ID: N/A, CIA: Harvey RP
William Buckland Foundation Grant, 1993, $17,500, ID: N/A, Harvey RP – CIA
Ian Potter Foundation Grant, 1992, $30,000, ID: N/A, CIA: Harvey RP
NHMRC; block grant to Walter and Eliza Hall Institute, 1992-1998, $200,000p/a, ID: N/A,
Lab head: Harvey RP
Clive and Vera Ramaciotti Foundation Grant, 1991, Amount: $40,000, ID: N/A, CIA: Harvey
RP
British Council Travel, 1991, $3,000, ID: N/A. CIA: Harvey RP
NIH NHLBI (USA) Research Grant (RO1), 1990-1992, $146,436, ID: N/A, PI: Harvey RP
MEMBERSHIP OF PROFESSIONAL SOCIETIES
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Australian Academy of Science (since 2007)
European Molecular Biology Organisation (since 2008)
Australia and New Zealand Society for Cell and Developmental Biology (President
2002-2003
Australian Society for Biochemistry and Molecular Biology (since 1998)
International Society for Stem Cell Research (since 03.05.2006)
SOCIETY CHAIRMANSHIPS
2002-2003
2000-2001
2000-2002
President, Australian and New Zealand Society for Cell and Developmental
Biology
Vice President, Australian and New Zealand Society for Cell and Developmental
Biology
President, Melbourne Developmental Biology Society
COMMITTEES AND ADVISORY BOARD
2011-Present
2011
2011-2012
2010-Present
2010
2009-Present
Scientific Leadership Group, ARC Special Research Initiative in Stem Cell
Science (Stem Cells Australia)
Member, NHMRC Grant Review Panel – Cell Biology and Regenerative
Medicine
Chair, Sectional Committee (Animal Sciences), Australian Academy of Science
Committee of the Australian and New Zealand Society of Cell and
Developmental Biology (senior consultancy body for President and Executive)
Scientific review of Medical Research Council (MRC), National Institute of
Medical Research (NIMR), Mill Hill, UK, Genetics and Development Group
(Director Jim Smith)
Garvan Institute /St. Vincent’s Hospital/ Victor Chang Cardiac Research Institute
campus Flow Cytometry Advisory Committee (Chair Anthony Baston)
Page 6 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2009-Present
2009-Present
2009-2010
2008
2008
2008-Present
2007-2010
2007
2006
2005-Present
2005-2010
2005-2010
2002-present
2002-2006
2002
2002-2009
2000
2000-2006
1999-2009
1998-Present
1997
1996-1997
1994-1997
1994-1995
1991-1996
Scientific Advisory Committee for inStem (Institute for Stem Cell Biology and
Regenerative Medicine), Bangalore, India
Alternative Member - Scientific and Medical Research Funding Working Group,
California Institute of Regenerative Medicine
Member, Sectional Committee (Animal Sciences), Australian Academy of
Science
NHMRC-initiated committee investigating allegations of scientific misconduct
Committee member for selection of Harrison Prize of International Society of
Developmental Biologists (to be presented at ISDB Congress 2009)
Governance Group, Congenital Heart Disease DNA Bank (Kids Heart Research
DNA Bank, Children's Hospital Westmead, Sydney, Australia
Member, Management Committee, Clive & Vera Ramaciotti Centre for Gene
Function Analysis
Ad Hoc Member, Australia Fellowship Committee
NHMRC Grant Review Panel (Genetics)
Member, Research Management Committee, University of New South Wales
Member Executive Advisory Committee, European Consortium Program Grant
“Heart failure and cardiac repair” (Director Antoon Moorman)
Member, Executive Advisory Committee, New South Wales Stem Cell Network
Chair, Faculty Committee, Victor Chang Cardiac Research Institute
Member, Executive Scientific Organisation Committee, Australian Stem Cell
Centre
NHMRC Grant Review Panel (Cell Biology and Biochemistry)
Member, Executive Scientific Advisory Board for ARC Special Centre for
Molecular Genetics of Development (Director Rob Saint)
Consultant for National Institute of Heart, Lung and Blood, NIH, Bethesda
USA for recruitment of a director for the new Developmental Biology Program
St Vincent’s Hospital/Garvan Institute Animal Ethics Committee
Intellectual Property Committee, Victor Chang Cardiac Research Institute
Appointments and Promotions Committee, Victor Chang Cardiac Research
Institute
Howard Florey Institute NHRMC Review Committee (Developmental Biology
Program)
WEHI, Genetic Manipulation Facility Management Committee
WEHI, Education and Seminars Committee Member
WEHI, Seminars Co-ordinator
Head, WEHI Centralised Blastocyst Injection Service
EDITORIAL BOARDS
2009-Present
2009-Present
2007-Present
2004-2007
2004-Present
2001-Present
Editorial Board Member, Circulation Research (American Heart Association)
(IF=9.21)
Editorial Board Member, Seminars in Cell and Developmental Biology
(Elsevier) (IF=6.48)
Editorial Board Member, Stem Cell Research (Elsevier) (IF=3.36)
Editorial Board Member, The Scientific World Journal (The Scientific
World) (IF not yet available)
Editorial Board Member, Developmental Dynamics (Wiley) (IF=2.83)
Associate Editor, Developmental Cell, (Cell Press) (IF=13.36)
Page 7 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2001-2003
2001-Present
2000-Present
Guest Editor, Mouse Knockout and Mutation Database (BioMedNet) (IF=
Not yet available)
Editorial Board Member: Developmental Biology (Elsevier) (IF=4.37)
Editorial Board Member: Trends in Cardiovascular Medicine (Elsevier)
(IF=4.36)
MANUSCRIPT, GRANT AND CAREER REVIEWING
Manuscripts:
Ad hoc reviewer for: Nature, Science, Genes and Development, Development, Mechanisms of
Development, Development Biology, Journal of Cell Biology, International Journal of
Developmental Biology, Proceeding of the National Academy of Sciences (USA), Molecular
Cell, Cell Stem Cell (approximate reviewing frequency: ~ 1-2 papers per week)
NHMRC grant review panels: 2002, 2006, 2011
Frequent Reviewer for:
 NHMRC
 ARC
 National Heart Foundation
 Welcome Trust
 Human Frontiers in Science
INVOLVEMENT IN APPOINTMENTS AND PROMOTIONS
Since 1998; British Heart Foundation (2x), London; National Institutes of Health USA (3X);
Medical College of Georgia, USA; Institute Pasteur, Paris; Weisman Institute, Israel; Mount
Sinai School of Medicine, New York, USA; University of California, San Francisco, USA
(2X); University of Sydney (3x), Australia; Monash University, Australia; University of
Queensland, Australia; Viertel Charitable Trust (Senior Medical Research Fellowship Scheme),
Australia; Washington University at St. Louis, USA.
THESIS REVIEW AND HIGHER DEGREE COMMITTEES
2008
2004
2004
2003
2002
2002
2001
2001
Kate Kollar, Mater Medical Research Institute, Queensland University of
Technology, Queensland, Australia (Confirmation of PhD candidature)
Alessandra Doolan, Centenary Institute, New South Wales, Australia (PhD
degree mid-point review)
Paul Robinson, Monash University (PhD thesis)
Gabriel Kolle, University of Queensland (PhD thesis)
Chris Hale, University of Auckland, New Zealand (PhD thesis)
Enoch Tay, Children’s Medical Research Institute, Australia (PhD mid-term
review)
David Pennisi, University of Queensland, Australia (PhD thesis)
Shen-Liang Chen, University of Queensland, Australia (PhD thesis)
Page 8 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
MAJOR CONFERENCE RESPONSIBILITIES
2012
2011
2010
2009
2009-Present
2009
2008
2008
2007-2009
2006
2005
2004
2004
2004
2003
2003
2001
2001
2001-Present
2001-2002
2000
2000
2000
Program Committee, International Society for Stem Cell Research (ISSCR),
Yokohama, Japan
Session Chair (Model Organisms and Therapies), 8th Indo-Australian
Biotechnology Conference on Stem Cell Biology, Bangalore, India
Session Chair (Organogenesis and Stem/Progenitor Cells), Cold Spring Harbor
Asia Meeting “Molecular Switches and Genome Function in Stem Cells and
Development”, Suzhou, China
Session Chair, International Society of Developmental Biologists Congress,
Edinburgh, UK; “Stem Cells and Medicine”.
Scientific Advisory Committee, Lorne Genome Meeting
Session Chair and Keynote Speaker, Keystone Meeting: Cardiac Disease:
Development, Regeneration and Repair, Ashfield, North Carolina
Convenor, Victor Chang Cardiac Research Institute Symposium, 2009:
“Cardiology at the Frontier – Development, Stem Cells and Heart Failure”
Session Chair, 15th International Vascular Biology Meeting, Convention Centre,
Sydney, Australia
International Advisory Committee, International Society of Developmental
Biologists Congress 2009 (Edinburgh)
Session Chair, half-day symposiums on Mesenchymal Stem Cells run by the
NSW Stem Cell Network, Sydney, Australia
Convenor, International Society of Developmental Biologists Congress,
Sydney, Australia
Session Chair, Australian Health and Medical Research Congress (21-26
November 04)
Co-Organiser with David Winlaw, Symposium: Building Bridges: Insights into
Congenital Heart Disease from Developmental Biologists, Morphologists and
Clinicians, Children’s Hospital at Westmead, Sydney, Australia (October 18th,
Sydney, Australia)
Session Organiser and Co-Chair, ComBio 2004, Perth, Western Australia
(September 26-30), Sydney, Australia
Session Chair, Second Stem Cell Workshop, New South Wales Stem Cell
Network, Sydney, Australia
Session Organiser and Chair, Hanson Institute, Stem Cell and Regeneration
Meeting, Barossa Valley, South Australia, Australia
Organising Committee and Convener, New South Wales Cell and
Developmental Biology Group
Symposium Chairman (Organogenesis), ComBio 2001
Organising and Planning Committee for the Annual Australian Developmental
Biology Workshop (co-organisers, P. Koopman, R. Saint, P, Tam)
Organising and Planning Committee for ComBio 2002
Co-Chairman; Symposium, Tissue Patterning and Organogenesis, International
Congress of Differentiation and Cell Biology, Gold Coast, Queensland,
Australia 1996
Co-Organiser Human Frontiers Science Program Meeting: “Genetic control of
heart development”, Strasbourg, France
Chairman: Developmental Biology Symposium, Australia Society for Medical
Research, Adelaide, Australia
Page 9 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
1997-2000
1996
Member of Organising Committee for the Annual EMBL (Germany)/Cold
Spring Harbour Laboratory (USA) Mouse Molecular Genetics Meeting
Session Chairman: American Heart Association: “Molecular biology of the
normal, hypertrophied and falling heart”, Snowbird, Utah, USA
NAMED, PLENARY AND SPECIAL LECTURES
2012, January
2011, December
2011, November
2011, August
2011, August
2010, November
2010, September
2010, May
2009, December
2009, March
2008, June
2008, April
2007, September
Plenary Speaker Keystone Symposium – “Cardiac Development and
Regeneration” Taos, New Mexico, USA “Defining the Cardiac Gene
Regulatory Network through Large Scale Transcription Factor Target
Site Profiling using DamID”
Keynote Lecture 8th Indo-Australia Biotechnology Conference on “Stem
Cell Biology”, InSTEM, Bangalore, India. “Characterisation and
Embryonic Origins of Adult MSC-like Stem Cells in the Mouse Heart”
Keynote Lecture Australia-France Joint Symposium on Health Sciences
and Biomedicine, National Academy of Sciences, Canberra, Australia.
“Endogenous cardiac MSC-like stem cells: characterisation and prospects
for participation in heart repair”
Keynote Lecture 15th New South Wales Stem Cell Network Workshop –
Stem Cells and Developmental Biology. “Characterisation of cardiacresident MSC-like stem cells in the mouse.”
Basic Science Lecturer, Cardiac Society of Australia and New Zealand.
“Linking development to regeneration in the developing heart”. CSANZ
annual meeting, Perth, Western Australia.
Bill Elliot Lecture, School of Molecular and Biomedical Science,
University of Adelaide, South Australia.
Lemberg Medal and Oration, Australian Society of Biochemistry and
Molecular Biology, OzBio2010, Melbourne, Australia. “Regulatory
networks in the developing heart”
Keynote Lecture: European Union FP6Consortium HeartRepair
Farewell Meeting, Amsterdam, Netherlands “Biology and origins of
cardiac-resident MSC-like stem cells”
President’s Medal Oration, Australian and New Zealand Society of Cell
and Developmental Biology, Combio2009 Meeting, Christchurch, New
Zealand
Keynote Speaker and Session Chair, Keystone Symposium – “Cardiac
Disease: Development, Regeneration and Repair”, Ashfield, North
Carolina, USA “Cardiac progenitor cell behaviour in development and
congenital heart disease”
Keynote Speaker, 15th International Vascular Biology Meeting
Convention Centre Sydney, Australia. “Transcriptional networks in
cardiac development”
Keynote Speaker, EU Consortium “HEARTREPAIR” 2nd Annual
Meeting, Madrid, Spain. “A hierarchy of multipotent, clonogenic and
self-renewing cells in the developing and adult murine heart”
Rosa Beddington Lecture, 19th Annual Mouse Molecular Genetics
Meeting (Welcome Trust Scientific Meeting), Sanger Institute,
Cambridge, UK; “Feedbacks and thresholds affecting progenitor cell
behaviour in the developing heart”
Page 10 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2007, June
2006, October
2005, January
2002, December
2002, December
2002, May
1998, February
1997, April
Keynote Speaker, Genetics Society of AustralAsia Meeting, Sydney,
Australia; “Cardiac development and congenital heart disease”
President’s Symposium Plenary Speaker, 14th International Society of
Differentiation and Cancer, “Cardiac development and congenital heart
disease” Innsbruck, Austria
Julian Wells Medal and Oration: Lorne Genome Meeting 2005.
“Cardiac development & congenital heart disease: Making the
connections”. Phillip Island, Australia (Interview published in Life
Scientist, January 2005)
Keynote Speaker, 5th Osaka Cardiovascular Research Forum. “Cardiac
Nkx2-5 homeobox gene pathways in development, evolution and
disease”, Tokyo, Japan
Keynote Speaker, Frontiers in Biomedical Research Symposium
marking the opening of the new Faculty of Medicine building. “Cardiac
Nkx2-5 homeobox gene pathways in development, evolution and
disease”, Hong Kong University, Hong Kong
Plenary Speaker, Cold Spring Harbour Laboratories 67th Symposium:
The Cardiovascular System; Cold Spring Harbor Laboratories, USA
“Homeobox factor Nkx2-5 in heart development and disease”
Inaugural Sir Peter Finley Lecture, “Cardiac development and heart
disease” The Victor Chang Cardiac Research Institute, Sydney, Australia
John H Blaffer Lecture, “Homeobox and bHLH genes in cardiac
development” MD Anderson Cancer Center, University of Texas,
Houston, Texas, USA
INVITED LECTURES (1990-PRESENT)
2012, May
2011, November
2011, June
2010, November
2010, July
2010, June
2010, April
2009, September
2009, August
Victoria Stem Cell Network, Melbourne Brain Centre, University of
Melbourne. “MSC-like stem cells in the mammalian heart”
Australian Regenerative Medicine Institute, Monash University, Victoria,
Australia. “MSC-like stem cells in the mammalian heart.”
BakerIDI, Melbourne, Victoria. “Biology and Origins of CardiacResident MSC-like Stem Cells”
Bill Elliot Lecture, School of Molecular and Biomedical Science,
University of Adelaide, South Australia. “Biology and Origins of
Cardiac-Resident MSC-like Stem Cells”
Peter MacCallum Cancer Research Institute, Melbourne, Australia;
“Cardiac-resident MSC-like stem cells: definition and origins”
University of California, San Francisco, Cardiovascular Research
Institute, San Francisco; “
University of New South Wales, School of Clinical Sciences, Sydney,
Australia; “A quantitative template for characterisation of cardiacresident stem cells”
Fundacion Centro Nacional de Investigaciones Cardiovasaculares Carlos
III, Madrid, Spain; “Cardiac progenitor cells in the embryo and adult:
towards a systems biology approach”.
National Centre for Adult Stem Cell Research, Eskitis Institute, Griffith
University, Queensland, Australia; “Quantitative template for analysis of
adult cardiac stem cells”.
Page 11 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2008, March
2007, November
2007, October
2007, April
2007, March
2006, October
2006, July
2006, May
2005, November
2005, April
2005, March
2005, March
2005, March
2004, August
2003, October
2003, July
2003, June
2003, May
2002, December
2002, November
2002, October
2002, September
2002, September
2002, June
2002, June
2002, May
Hanson Institute, Institute of Medical and Veterinary Science, Adelaide,
Australia; “A hierarchy of multipotent, clonogenic and self renewing
cells in the developing and adult murine heart”.
Bernard O’Brien Microsurgery Institute, Melbourne, Australia:
“Multipotent cells in the development and adult murine heart”
Skirball Institute, New York; “Thresholds and control of biological noise
in the left/right pathway”
The Murdoch’s Children’s Research Institute, Melbourne, Australia;
“Nkx2-5/Bmp2/Smad1- negative feedback loop controls cardiac
progenitor cell specification and proliferation”
National University of Singapore; Nkx2-5/Bmp2/Smad1 negative
feedback loop controls cardiac progenitor cell specification and
proliferation”
Pasteur Institute, Department of Developmental Biology, Paris, France;
“An Nkx2-5/Bmp2/Smad1-dependent negative feedback loop controls
cardiogenesis”
University of Sydney, School of aerospace, Mechanical and Mechatronic
Engineering, “Stem cells, stem cell therapy and tissue engineering”
University of New South Wales, School of Biotechnology and
Bimolecular Science, “Stem cells, stem cell therapy and tissue
engineering”
Johnson and Johnson, Australia Technology Park, Sydney, Australia,
“Prospects for cardiac regeneration”
University of Sydney, Australia. “Role of homeodomain transcription
factor Nkx2-5 in heart development”
Children’s Medical Research Institute, Sydney, Australia. “Cardiac
progenitor cells – a role in instructing neural crest”
Centre for the Molecular Genetics of Development, University of
Adelaide, Adelaide, South Australia. “Cardiac homeodomain
transcription factor plays a repressive role in early cardiac development”
Centre for the Molecular Genetics of Development, Australian National
University, Canberra, Australia. “Cardiac homeodomain transcription
factor plays a repressive role in early cardiac development”
Kolling Institute, Sydney, Australia
Institute for Reproduction and Development, Monash University,
Melbourne, Australia
Department of Cell Biology and Anatomy, University of Tuscon,
Arizona, USA
Allen’s, Arthur, Robinson Biotech/Health Forum, Sydney, Australia
School of Biomedical Sciences, University of Queensland, Australia
RIKEN Institute of Developmental Biology, Kobe, Japan
Prince of Wales Hospital, Sydney, Australia
Institute Pasteur, Paris
Institute of Molecular and Cell Biology, Singapore
Institute for Stem Cell Research, Edinburgh, UK
Children’s Medical Research Institute, Sydney, Australia
Pfizer, Connecticut, USA
Department of Biochemistry and Biophysics, University of California,
San Francisco, USA
Page 12 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2002, May
2002, May
2001, July
2001, June
2000, September
1999, November
1999, October
1999, October
1999, September
1999, June
1999, March
1998, November
1998, September
1998, July
1998, March
1998, March
1997, March
1997, November
1997, August
1997, April
1996, December
1996, September
1996, September
1996, June
1996, February
1995, July
1995, June
1995, May
1995, April
1995, March
1994, June
1994, May
1994, April
1994, April
1994, April
1994, February
Walter and Eliza Hall Institute of Medical Research, Melbourne,
Australia
Centenary Institute, Sydney, Australia
Garvan Institute for Medical Research, Sydney, Australia
Hanson Center for Cancer Research, Adelaide, Australia
National Institute for Heart, Lung and Blood, National Institutes of
Health, Bethesda, Maryland, USA
Center for Molecular Biology and Biotechnology, Brisbane
Ludwig Institute for Medical Research, Melbourne
Department of Biochemistry, University of New South Wales, Sydney,
Australia
Marseille Institute for Developmental Biology, Marseille, France
Hospital of the University of Pennsylvania, Cardiology Division,
Philadelphia, USA
Cardiovascular Research Club, University of Sydney/Royal North Shore
Hospital, Sydney, Australia
St Vincent’s Hospital, Sydney, Australia
Department of Biochemistry and Biophysics, University of California,
San Francisco, USA
Howard Florey Institute of Experimental Medicine and Physiology,
Melbourne, Australia
Department of Biochemistry, University of Sydney, Sydney, Australia
University of Chicago, Section of Cardiology, Chicago, USA
Children’s Medical Research Institute, Sydney, Australia
Biochemistry Department, University of Sydney, Sydney, Australia
Institute Pasteur, Paris, France
Clinical Research Institute of Montreal, Montreal, Canada
Institute of Molecular Biology and Biotechnology, University of
Queensland, Brisbane, Australia
Cardiovascular Research Institute, Massachusetts General Hospital,
Harvard Medical School, Boston, USA
Skirball Institute, New York University, New York, USA
Ludwig Institute for Cancer Research, Melbourne, Australia
South-Western Medical Centre, Hamon Center for Basic Cancer
Research, Dallas, Texas, USA
Department of Biochemistry and Biophysics, University of California,
San Francisco, USA
Victor Chang Cardiac Research Institute, Sydney, Australia
Department of Genetics and Human Variation, La Trobe University,
Melbourne, Australia
Department of Genetics and Developmental Biology, Monash University,
Australia
Department of Anatomy and Cell Biology, University of Melbourne,
Australia
Murdoch Institute, Melbourne, Australia
Ludwig Institute for Cancer Research, Melbourne, Australia
Department of Medicine, University of California, San Diego, USA
Loyola University of Chicago Stritch School of Medicine, Chicago, USA
Massachusetts General Hospital, Boston, USA
Centre for Molecular Biology and Biotechnology, Brisbane, Australia
Page 13 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
1993, October
1993, October
1993, September
1993, June
1993, April
1992, July
1992, June
1991, October
1991, March
1991, January
1990, November
Austin and Repatriation Hospital, Melbourne, Australia
Baker Medical Research Institute, Melbourne, Australia
CSIRO Division of Bimolecular Engineering, Melbourne, Australia
Children’s Medical Research Institute, Sydney, Australia
Russell Grimwade School of Biochemistry, University of Melbourne,
Melbourne, Australia
Centre for Molecular Biology and Biotechnology, Brisbane, Australia
Department of Genetics, La Trobe University, Melbourne, Australia
Department of Zoology, La Trobe University, Melbourne, Australia
Children’s Medical Research Foundation, University of Sydney, Sydney,
Australia
Institute of Haematology, People’s Hospital, Beijing Medical University,
Beijing, China
Department of Genetics, University of Melbourne, Melbourne, Australia
INVITED PLATFORM MEETING PRESENTATION (1990-PRESENT)
2012, January
2012, January
2011, December
2011, November
2011, September
2011, August
2011, August
2011, July
2010, November
2010, September
Plenary Speaker Keystone Symposium – “Cardiac Development and
Regeneration” Taos, New Mexico, USA “Defining the Cardiac Gene
Regulatory Network through Large Scale Transcription Factor Target
Site Profiling using DamID”
Cardiovascular Research Institute (UCSF; USA)/Victor Chang Cardiac
Research Institute (Australia) Joint Symosium. “Cardiovascular
Development”
Keynote Lecture 8th Indo-Australia Biotechnology Conference on “Stem
Cell Biology”, InSTEM, Bangalore, India. “Characterisation and
Embryonic Origins of Adult MSC-like Stem Cells in the Mouse Heart”
Keynote Lecture Australia-France Joint Symposium on Health Sciences
and Biomedicine, National Academy of Sciences, Canberra, Australia.
“Endogenous cardiac MSC-like stem cells: characterisation and prospects
for participation in heart repair”
Australian Vascular Biology Society 19th Annual Meeting, Bowral,
NSW, Australia. “Cardiac-resident MSC-like stem cells”
Keynote Lecture 15th New South Wales Stem Cell Network Workshop –
Stem Cells and Developmental Biology. “Characterisation of cardiacresident MSC-like stem cells in the mouse.”
Basic Science Lecturer, Cardiac Society of Australia and New Zealand.
“Linking development to regeneration in the developing heart”. CSANZ
annual meeting, Perth, Western Australia.
American Heart Association Basic Cardiovascular Science Meeting, New
Orleans, Louisiana, USA. “Characterisation and Origins of Endogenous
Cardiac MSC-like Stem Cells”
Annual Meeting of the Institute for Stem Cell Biology and Regenerative
Medicine (inStem), Bangalore, India. “Biology and lineage origins of
adult cardiac stem cells in the mouse”
Lemberg Medal and Oration, Australian Society of Biochemistry and
Molecular Biology, OzBio2010, Melbourne, Australia. “Regulatory
networks in the developing heart”
Page 14 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2010, September
2010, June
2010, May
2010, March
2010, March
2010, February
2009, December
2009, October
2009, September
2009, March
2009, March
2008, July
2008, July
2008, June
2008, June
2008, April
Cold Spring Harbor Asia Conference - Molecular Switches and Genome
Function in Stem Cells and Development, Suzhou, China. “Biology and
lineage origins of adult cardiac stem cells in the mouse”
International Society of Stem Cell Research 8th Annual Meeting, San
Francisco, USA; “Lineage Origins of Adult Cardiac Stem Cells in the
Mouse” [selected from abstracts]
Keynote Lecture: European Union FP6Consortium HeartRepair
Farewell Meeting, Amsterdam, Netherlands “Biology and origins of
cardiac-resident MSC-like stem cells”
Hunter Cellular Biology Meeting, Hunter Valley, New South Wales,
Australia “Adult cardiac stem cells and the pericyte continuum”
Hunter Cellular Biology Meeting (Imaging Workshop), Hunter Valley,
New South Wales, Australia “Imaging of congenital heart disease”
Keystone Meeting - Cardiac Diseases: Development, Regeneration and
Repair, Keystone Colorado, USA. “The pericyte continuum in heart
development and repair”
Australian and New Zealand Society of Cell and Developmental
Biology President’s Medal Oration, Combio2009 Meeting,
Christchurch, New Zealand. “The developing heart: ancient core, fragile
form”
Victor Chang Cardiac Research Institute International Symposium –
Cardiology at the Frontier: Development, Stem Cells and Heart Failure,
Sydney, Australia; “Cardiogenesis and congenital heart disease: probing
the regulatory landscape”
International Society of Developmental Biologists Congress, Edinburgh,
UK; Cardiac Transcription Factors in Development and Disease”.
Keynote Speaker and Session Chair, Keystone Symposium – “Cardiac
Disease: Development, Regeneration and Repair”, Ashfield, North
Carolina, USA “Cardiac progenitor cell behaviour in development and
congenital heart disease”
National Centre for Biological Sciences, Bangalore, India (symposium
for Working Group for establishment of Stem Cell Institute, Bangalore)
“Quantitative framework for analysis of adult cardiac stem cells”
American Heart Association Basic Cardiovascular Sciences Annual
Conference 2008: “Heart Failure: Molecular Mechanisms and
Therapeutic Targets” Keystone Colorado, USA. “Nkx2-5/Bmp2 pathway
in cardiac progenitor specification”
Genetics Society of Australasia Annual Scientific Meeting, Adelaide,
Australia; “Overlapping roles for Bmp/Smad signalling in heart
development”
Sydney Cardiac Club, Sydney, Australia; “Endogenous cardiac stem
cells: a quantitative approach”
Centenary Institute Symposium: “Opportunities in Stem Cells” Sydney,
Australia; “A hierarchy of clonogenic, self-renewing and multipotent
stem cells in the adult murine heart”
European Union Consortium HEARTREPAIR 2nd Annual Meeting,
Madrid, Spain. “Thresholds and management of biological noise in the
left/right pathway”.
Page 15 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2008, April
2008, March
2008, February
2007, November
2007, October
2007, September
2007, September
2007, August
2007, August
2007, June
2007, June
2007, May
2007, April
2006, October
2006, March
Keynote Speaker, European Union Consortium HEARTREPAIR 2nd
Annual Meeting, Madrid, Spain. “A hierarchy of multipotent, clonogenic
and self-renewing cells in the developing and adult murine heart”.
Australian Stem Cell Centre Adult Stem Cell Workshop 2008. University
of Queensland, Australia; “A hierarchy of multipotent, clonogenic and
self-renewing cells in the developing and adult murine heart”.
Lorne Genome Meeting, Lorne, Victoria, Australia; “Thresholds and
management of intrinsic biological noise: the BMP/Smad1 signalling
system provides a buffer against precocious activation of the nodal
left/right asymmetric organ development pathway”.
Victor Chang Cardiac Research Institute Princesses’ Lecture Symposium,
Cardiology at the Frontier. Victor Chang Cardiac Research Institute,
Sydney, Australia. “Origins of the conduction system and
arrhythmogenic tissue in the developing heart”.
NHLBI Symposium on Cardiovascular Regenerative Medicine, National
Institutes of Health, Bethesda, MA, USA; “Multipotent progenitor cells
in the developing and adult murine heart”.
Combio 2007, Sydney, Australia; “Thresholds and management of
biological noise in the left/right pathway”.
Rosa Beddington Lecture, Mouse Molecular Genetics Meeting, Sanger
Centre, Hixton, UK; “Cardiac development and congenital heart disease”.
Inaugural Annual Stem Cell Symposium at UNSW, Prince of Wales
Hospital, Sydney, New South Wales, Australia. “Endogenous cardiac
stem cells and capacity for heart regeneration”
Inaugural Australian Phenomic Stem Cell Initiative Workshop, John
Curtin School of Medicine, Australian National University, Canberra,
Australia. “Endogenous cardiac stem cells: definition, characterisation
and quantification”
Plenary Speaker, Genetics Society of Australia Meeting, University of
Sydney, Sydney, Australia “Cardiac development and congenital heart
disease”
International Society of Stem Cell Research Meeting, “Identification and
quantification of multipotent stem cells in the mammalian heart”, Cairns,
Australia
Gordon Conference: Myogenesis; II Ciocco Resort, Italy “Coordination
of the multiple roles of Bmps in the cardiogenesis”
Stem Cell Workshop: Bridging the gap-drug discovery and regenerative
medicine (Invitation only meeting run by Department of Education,
Science and Training, and Academy of Technological Science and
Engineering), Sydney, Australia “Stem cells and heart repair: prospects
for endogenous regeneration”.
President’s Symposium Plenary Speaker, 14th International Society of
Differentiation Conference, “Order and Disorder in Differentiation and
Cancer”, Innsbruck, Austria; “An Nkx2-5/Bmp2/Smad1 – dependant
negative feedback loop controls cardiogenesis”.
National Heart Foundation of Australia Inaugural Heart Foundation
Conference and Scientific Meeting, Convention Centre, Sydney,
Australia; “Cardiac transcription factors and congenital heart disease”
Page 16 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2006, March
2005, November
2005, September
2005, April
2005, March
2005, March
2005, February
2004, November
Mater Medical Research Institute, 3rd Annual Stem Cell Symposium
“Basic science and clinical applications of mesenchymal and
haematopoietic stem cells”.
Australian Stem Cell Centre Retreat, Melbourne Australia. Heart Repair
Regeneration
Combio 2005, Adelaide, Australia. “Nkx2-5 negatively regulates multiple
stages of early cardiogenesis”
Hunter Valley Cell Biology Meeting, The Sebel-Kirkton Park, Hunter
Valley, New South Wales, Australia (withdrawn ill)
Mammalian Genome-Phenome Code Meeting, Australian National
University, Canberra, Australia
Victor Chang Cardiac Research Institute/Centre for Vascular Research,
UNSW, joint retreat; Crown Plaza, Coogee, New South Wales, Australia
Lourne Genome Meeting, Phillip Island, Victoria, Australia (winner:
Wells Medal and Oration)
New South Wales Cardiovascular Genetics Workshop; Sydney, Australia
Page 17 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2004, October
2004, May
2004, March
2004, March
2004, February
2003, November
2003, October
2003, October
2003, August
2003, May
2002, December
2002, November
2002, September
2002, May
2002, April
2002, April
2001, November
2001, September
2001, August
2001, July
2001, June
2001, April
2000, September
2000, September
2000, June
2000, February
1999, November
1999, November
Symposium: “Building Bridges: Insights into Congenital Heart Disease
from Developmental Biologists, Morphologists and Clinicians”,
Children’s Hospital at Westmead, Sydney, Australia (October 18th,
Sydney Australia)
EMBO Workshop: “Myogenesis” II Ciocco, Italy
Victor Chang Cardiac Institute Symposium: “A Day of Science” Sydney,
Australia
Keystone Symposium “Cardiac Development and Congenital Heart
Disease” Keystone, Colorado, USA
Keystone Symposium, Santa Fe, New Mexico, USA “Signalling in
Vertebrate Organogenesis”
“Science amongst the Vines” meeting of the Hanson Institute of Cancer
Research Australia, Barossa Valley, South Australia “Regeneration”
First Australian Stem Cell Centre Conference, Melbourne, Australia
Australian Developmental Biology Workshop 2003, Sydney, Australia
Society for Developmental Biology Meeting, Boston, USA
Osaka International Audio Conference, Osaka, Japan
Japanese Society of Molecular Biologists Meeting, Yokahama, Japan
Stem Cell Workshop, University of New South Wales, Sydney, Australia
EMBO Workshop, Cambridge, UK, “Molecular genetics of myogenesis
and muscle diseases”.
XIVth World Congress of Cardiology, Sydney, Australia
Cold Spring Harbor Laboratories Meeting: Evolution of Developmental
Mechanisms. Cold Spring Harbor Laboratories, USA
Hunter Valley Cell Biology Meeting, Hunter Valley, Australia
1st Australian Developmental Biology Workshop, Victor Harbour,
Australia
Satellite Meeting of the 34th International Congress of Physiological
Sciences: Muscle Fibre Types: Development, Function and Regulation.
Sydney, Australia
34th International Congress of Physiological Sciences, Christchurch, New
Zealand
Mundaring Weir Symposium, University of Western Australia, Australia
Symposium of Physiological Genomics, University of Sydney, Australia
Myogenesis Gordon Conference, II Ciocco Italy
International Congress on Cell and Developmental Biology, Gold Coast,
Queensland, Australia
Mouse Molecular Genetics Meeting, Cold Spring Harbor Laboratories,
Cold Spring Harbor, New York, USA
Department of Molecular Genetics and Development, University of
Adelaide: Symposium to celebrate opening of new departmental building.
Adelaide, South Australia, Australia
Baker Institute Symposium – Cardiovascular Genetics, St Kilda, Victoria,
Australia
Australian Society for Medical Research 38th National Scientific
Meeting, Leura, New South Wales, Australia
Victor Chang Cardiac Research Institute Symposium, Sydney, Australia
“Muscle development, adaptation and hypertrophy: Implications for
cardiovascular and musculoskeletal diseases”
Page 18 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
1999, September
1999, June
1999, June
1999, June
1998, November
1998, November
1998, November
1998, August
1998, March
1997, April
1997, April
1997, May
1997, November
1997, December
1996, December
1996, November
1996, October
1996, September
1996, August
1996, August
1996, March
1996, February
EMBO Workshop: Molecular Genetics of Muscle Development and
Neuromuscular Disease, Kloster, Irsee, Germany, “NK homeobox gene
pathways in cardiac and visceral muscle”
Cold Spring Harbor Course: Molecular Embryology of the Mouse, (2
Lectures), Cold Spring Harbor, USA “Heart Development”
58th Annual Meeting of the Society for Developmental Biology,
Charlottesville, Virginia, USA “Role of homeodomain Factor Nkx2-5 in
cardiac development and disease”
Samuel Lunenfeld Research Institute of Mount Sinai Hospital 5th Annual
Symposium: Pathways of Development and Disease, Toronto, Canada
“NK2 homeobox genes in development and disease”
Transgenic Approaches in Biomedical Research (In honour of Richard
Palmiter), Garvan Institute, Sydney, Australia “Mouse genetic technology
in the study of heart development”
Australian Birth Defects Society Meeting, Royal Hospital for Women,
Sydney, Australia, “Homeobox Gene Nkx2-5 and its role in cardiac
development in mice and humans”
Sydney Transcription Group Meeting, Royal North Shore Hospital,
Sydney, Australia “The cardiac NK-2 class homeobox genes: structure,
function and evolution”
BCCH Symposium: Baker Medical Research Institute, Melbourne,
Australia “Cardiac development: Implications for heart disease”
Keystone Meeting: Molecular Biology of the Cardiovascular System,
Steamboat Springs, Colorado, USA “Homeodomain genes in control of
cardiac development”,
Keystone Symposium, Snowmass, Colorado, USA, “Molecular biology
of muscle development”
European Science Foundation Forth International Workshop,
Villefranche-sur-Mer, France, “The genetic control of vertebrate
development”
Cold Spring Harbor LXII Symposium, Cold Spring Harbor Laboratories,
“Pattern formation during development” USA
Cold Spring Harbor Banbury Meeting, The Banbury Centre, Cold Spring
Harbor, USA “Handedness and symmetry in development”,
Pfizer Japan Audio Conference to University of Tokyo, Japan ,“Linage
specification and patterning during vertebrate heart development”
The Victor Chang Cardiac Research Institute, Sydney, Australia,
“Molecular Structure, Function and Development of the Heart”,
Howard Florey Institute of Experimental Medicine and Physiology,
“Biomedical science in the 21st century”, Melbourne, Australia
Human Frontiers Science Program Specialist Meeting: “Genetic Control
of Heart Development”, Strasbourg, France
Cold Springs Harbor Meeting: Mouse Genetics, Cold Spring Harbor,
New York, USA
American Heart Association: “Molecular Biology of the Normal,
Hypertrophied and Failing Heart”, Snowbird, Utah, USA
First Xenopus Heart Development Meeting, Snowbird, Utah, USA
EMBL Workshop: “Myogenesis and Neuromuscular Diseases”, Ein Gedi,
Israel
The Genome Conference, Lorne, Australia
Page 19 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
1996, February
1995, August
1995, July
1994, July
1994, April
1994, February
1993, November
1993, December
1993, July
1993, April
1993, January
1992, September
1992, August
1992, February
1991, August
1991, July
1991, February
1990, August
Keystone Symposium: Cardiovascular Development, Keystone,
Colorado, USA
EMBL Conference: Mouse Molecular Genetics, Heidelberg, Germany
Gordon Conference: Myogenesis, Tilton, New Hampshire, USA
Melbourne Neuromuscular Research Centre, Melbourne, Australia,
“Control of Muscle Development: Growth Factors, Gene Regulation and
Potential for Therapy”,
Keystone Meeting: Molecular Biology of Muscle Development, Utah,
USA
The Genome Conference, Lorne, Australia
Thirty-Second National Australian Society for Medical Research
Conference, Adelaide, Australia
Cellular Signalling, Implications for Cardiovascular Physiology and
Medicine, Melbourne, Australia
Australian Society for Biochemistry and Molecular Biology, Adelaide,
Australia
Genes and Development Meeting, Monash University Institute of
Development and Reproduction, Melbourne, Australia
The Robertson Symposium: “Frontiers of Molecular Evolution”,
Canberra, Australia
EMBO Workshop: “Molecular Biology and Pathology of Skeletal and
Cardiac Myogenesis”, Alghero, Italy
Queenstown Molecular Biology Meeting, Queenstown, New Zealand
The Genome Conference, Lorne, Australia
The Seventh Welcome Summer School: “Gene Targeting and
Homologous Recombination”, London, UK
Australian Society for Biochemistry and Molecular Biology Meeting,
Canberra, Australia
Australia and New Zealand Society for Cell Biology, Adelaide, Australia
“Cell and Molecular Biology of Xenopus Development”, Les Diablerets,
Switzerland
MEETING, WORKSHOPS AND COURSES ATTENDED (2001-PRESENT)
2006
2001
Biology of Shape Meeting (Cell Press) Barcelona, Spain
International Congress of Developmental Biology, Kyoto, Japan
UNDERGRADUATE AND GRADUATE TEACHING LECTURES (1990-PRESENT)
2007
2006
2006
2002
National University of Singapore, Tamasek Life Science Laboratory;
Two PhD Program lectures: “Building blocks of the mammalian heart”
and “Cardiac stem cells: prospects for endogenous regeneration”
University Of Sydney, School of Aerospace, Mechanical & Mechatronic
Engineering J07. “Cardiac development, stem cells and tissue
engineering”
2hr lecture on Cardiac Development and Stem Cells for UNSW Masters
Course BIOT7072 on Eukaryotic Cell Physiology and Stem Cell Biology
PhD Course Lecture, Walter Eliza Hall Institute of Medical Research,
Melbourne, Australia
Page 20 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
1999
1994
1993
1992
1 lecture and Tutorial, 3rd year Science and Medicine, Department of
Medicine, University of NSW, Sydney, Australia
2 lectures, 3rd year Science, Department of Anatomy and Cell biology,
University of Melbourne, Melbourne, Australia
2 lectures, 3rd year Science, Department of Anatomy and Cell Biology,
University of Melbourne, Melbourne, Australia
2 lectures, 3rd year Science, Department of Anatomy and Cell Biology,
University of Melbourne, Melbourne, Australia
WIDER COMMUNITY ACTIVITIES AND MEDIA EXPERIENCE
2010
2009
2007
2007
2005
2005
2004
2002-2003
2002
1998
Represented Australian Academy of Science at Science Week launch
Interviewed for News Bulletin of HeartRepair, a European Union Sixth
Framework Programme Integrated Project (LSHM-CT-2005-01860),
published September 2009
Lay Lecture to National Heart Foundation Donors Group
Radio interviews with Youth Radio Melbourne and Radio National News
on involvement of TBX20 gene mutations in congenital heart disease
Interviewed by Sydney Morning Herald for a health and science piece on
holes in the hearts in adults (“There’s a hole in my heart” SMH April 28th
2005, Page 6; author: Judy Skatssoon)
Interview published in Life Scientist (January edition) in association with
award of Genome Conference Julian Wells Medal and Oration
Profiled in Sydney Morning Herald’s Labwatch (11.11.04)
Lay Lecture to Bondi Junction Probus Club
Interview for TVB Cantonese Cable TV on Stem Cells
Lay Lecture to Silverwater Rotary Club
SUPERVISED STUDENTS, POSTDOCTORAL FELLOWS AND RESEARCH STAFF
NAME
Thierry Lints
Ian Lyons
POSITION
PhD Student
Postdoctoral Fellow
Linda Parsons
PhD Student, University 1992 – 1996
of Melbourne
Jane Andrews
Craig Newman
Honours Student
University of Melbourne
Postdoctoral Fellow
PhD Student /
Postdoctoral, University
of Melbourne
Visiting PhD Student
Mary Familari
Postdoctoral Fellow
Matthijs Smith
David Elliott
TENTURE
1989-1993
1990-1993
1993
1993-1994
1995-2003
April –
June 1995
Feb –
Aug 1995
NEXT OR CURRENT POSITION
Assistant, City College of New York, NY, USA
Stem Cell Innovations, Amphioxus Cell
Technologies, Inc. 11222 Richmond Ave, Suite
180 Houston, TX 77082, USA
Postdoctoral with Phil Ingram, ICRF, London, UK;
maternity leave; Postdoctoral with Helena
Richardson, Peter MacCallum Cancer Institute,
Melbourne, Australia
Postdoctoral with Jim Smith, MRC Institute of
Medical Research, Mill Hill, London
Patent Law
Research Scientist, Monash Medical Research
Institute, Australia
PhD Student with Paul Krieg, University of Texas,
Austin, Texas, USA
Senior Research Fellow, Department of Medicine,
Western Hospital, Footscray, Australia
Page 21 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Jan 1997 –
Feb 2001
Chengchun Wang PhD Student of
July 1995 –
University of Melbourne May 2000
Eduard Stanley
Postdoctoral Fellow
March 1996 –
March 1998
Stephen Palmer
Postdoctoral Fellow
David Whyatt
Postdoctoral Fellow
Christine Biben
Aaron Schindler
Postdoctoral Fellow
May 1995
PhD Student, University April 1998 –
of New South Wales
2003
Quyen Trihn
Honour Student,
University of New South
Wales
PhD Student, University
of New South Wales
Postdoctoral
Fellow
Research Assistant
Donna (Yang) Li
Donna (Yang) Li
Lachlan
McDonald
Thomas Yeoh
Edwin Kirk
Mark Solloway
Fiona Stennard
Owen Prall
March –
Dec 1996
2000
5 May –
Dec 2003
Jan 2004 –
Aug 2006
Jan1999 –
June 2001
PhD Student, University Feb1999 –
of New South Wales
Feb 2003
PhD Student, (part time), Jan 2000 –
University of New
Jan 2008
South Wales
Post Doctoral
May 2000 –
Fellow
July 2005
Postdoctoral fellow
May 2000–
July 2005
Postdoctoral Fellow
May 2000Dec 2008
Joan Li
Research Assistant/ PhD Sept 2001 –
Student, University of
2008
New South Wales
Postdoctoral Fellow
2004-2006
Mauro Costa
Postdoctoral Fellow
Sept 2001 2008
Lopeti Lavulo
Postdoctoral Fellow
Jan 2002 –
May 2004
Milena Furtado
Research Scientist, Children’s Medical Research
Institute, Sydney, Australia
Postdoctoral Fellow with Dr WJ Hong, Institute of
Molecular and Cell Biology, Singapore
Full Professor, Group Leader, Monash Immunology
and Stem Cell Laboratories, Monash University,
Melbourne, Australia
Senior Research Fellow, Department of Cell
Biology and Genetic, Erasmus University,
Rotterdam, The Netherlands
Travel
Research Scientist | Orthopaedic Research &
Biotechnology, Kids Research Institute at The
Children's Hospital at Westmead, Sydney,
Australia
Unknown
Postdoctoral Fellow, Victor Chang Cardiac
Research Institute, Sydney, Australia
Molecular Biology Officer, Bosch Institute,
University of Sydney, Australia
Territory Manager, NSW
Qia gen Pty Ltd, Sydney, Australia
Cardiologist, Concord & Canterbury Hospitals,
Sydney, Australia
Clinical Geneticist, Sydney Children’s Hospital,
Randwick, Sydney, Australia
Senior Scientist, Molecular Biology Department,
Genetech, California, USA
Maternity Leave
Specialisation in Anatomical Pathology, Royal
Melbourne Hospital, Melbourne Australia;
Laboratory Head, Walter and Eliza Hall of
Medical Research; Melbourne, Australia.
Post-doctoral Fellow, Laboratório de Morfogênese
Cellular –Instituto de Ciências Biomédicas Universidade Federal do Rio de Janeiro - Brazil
Postdoctoral Fellow, Australia Stem Cell Centre,
Institute for Molecular Biosciences,
The University of Queensland NSW
Adjunct Professor, Instituto de Bifisica Carlos
Chagas Filho, Universidade Federal do Rio de
Janeiro, Brazil
Senior Scientist, Bioline Australia; Sydney,
Australia.
Page 22 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Changbaig Hyun
Postdoctoral Fellow
Sep 2002 –
Feb 2004
Daniel Schaft
Savita Kurup
Postdoctoral Fellow
Postdoctoral Fellow
Oct 2003 Oct 2003 –
June 2005
Alex Cheung
Postdoctoral Fellow
May 2004 –
July 2006
Feb 2002 –
Oct 2002
Martin Lange
Visiting German
Oct 2002 –
Student
Dec 2002
Ishtiaq Ahmed
PhD Student; enrolled
July 2004University of Durham
Sept 2008
Orit Wolstein
Postdoctoral Fellow
Jan 2005 –
June 2011
Romaric Bouveret Postdoctoral Fellow
Feb 2006 Vashe
Postdoctoral Fellow
April 2006 –
Chandrakanthan
June 2010
James Chong
PhD Student University Feb 2007 –
of New South Wales
Nov 2010
Munira
Postdoctoral Fellow
Aug 2006-July
Xaymardan
2007;
July 2008 –
Mar 2012
Naisana Asli
Postdoctoral Fellow
Jan 2009Stella Li
Postdoctoral Fellow
Feb 2009Dec 2009
Mhadi Moradi
PhD Student
Feb 2009 Tram Doan
Bioinformaticist
Feb 2009Nov 2011
Xiaohang Lani Li Postdoctoral Fellow
March 2009 Dec 2009
Danielle de Jong Postdoctoral Fellow
June 2009 –
Oct 2011
Amita Lamaye
Postdoctoral Fellow
Sept 2009 Helen
Honours Student,
July 2009Malinowska
University of New
June 2010
South Wales
Shanthosh
ILP Student, University May 2009 –
Sivpathan
of New South Wales
March 2010
Mirana
Postdoctoral Fellow
Feb 2010Ramialison
Sharon Pursglove Postdoctoral Fellow
Jan 2010 –
Saskia Haast
Visiting Dutch Student
Section Head/Assistant Professor, College of
Veterinary Medicine, Kangwon National
University, Chunchol, South Korea
Patent Law
Postdoctoral Scientist and Manager, Newborn
Care and Maternal-Fetal Medicine Research Lab,
Royal Hospital for Women; Prince of Wales
Hospital, Sydney, Australia.
Scientific Officer, Department of
Rehabilitation Sciences, The Hong Kong
Polytechnic University.
Completion of Science Degree, Free University,
Amsterdam, The Netherlands
PhD in Laboratory of Silke Sperling, Max-PlanckInstitute for Molecular Genetics, Berlin, Germany
Advanced Trainee Special Registrar,
Cardiothoracic Surgery. North Deanship, UK.
Clinical Trials Manager, St. Vincent’s Hospital,
Sydney Australia
Research Fellow, Adult Cancer Research Program,
UNSW
Postdoctoral Fellow, Laboratory of Charles Murry,
University of Washington, Seattle, USA
Lecturer, Faculty of Medicine, Univesity of Sydney;
Consultant, Victor Chang Cardiac Research
Institute
Law student, University of New South Wales
PhD student and part time bioinformatician,
Westmead Institute for Cancer Research, Australia
Scientist, Sydney University
Postdoctoral Fellow, laboratory, Hawaii, USA
Genetic counselling
Medical Student, UNSW
Page 23 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Li Xin
Nicole Schonrock
Reena Singh
Gonzalo del
Monte Neto
Henrik Reinhard
Alexis Bosman
Ashley
Waardenberg
Postdoctoral Fellow
Postdoctoral Fellow
Postdoctoral Fellow
Postdoctoral Fellow
Nov 2010 Jan 2011 April 2011June 2011-
Postdoctoral Fellow –
Sept 2011 Prince Christian Fellow
Postdoctoral Fellow
Dec 2011 Postdoctoral
March 2012 Fellow/bioinformatician
PhD STUDENTS AND POSTDOCTORAL FELLOWSHIPS AWARDS
Year
Name
Source
Duration
2001 –
2002
2001 –
2003
2001 –
2004
2002 –
2004
2003 –
2005
2004 –
2005
2005 –
2007
2006 2007
2007
Mauro Costa
CAPES (Brazil)
2 Years
Total Amount
(AUD)
$39,000
Mark Solloway
NIH (USA)
3 years
$156,810
Owen Prall
Doherty NHMRC
4 Years
$271,538
Edwin Kirk
National Heart Foundation
3 Years
$81,000
Thomas Yeoh
NHMRC PhD Fellowship
3 Years
$117,750
Daniel Schaft
DFG (Germany)
2 Years
$64,670
Daniel Schaft
HFSP
3 Years
$220,000
Romaric Bouveret
Swiss National Science Foundation 1 Year
$44,500
Milena Furtado
$17,571
2007 2008
Romaric Bouveret
National Heart Foundation PhD 9 Months
Fellowship
UNSW Vice Chancellor
2 Years
Postdoctoral Research Fellowship
Australian Research Coucil
Australian Postdoctoral
Fellowship
National Heart Foundation PhD
Fellowship
3 Years
$275,766
3yrs
$126,000
1yr
$US34,000
2 years
$128,240
20092011
20082010
20082009
James Chong
Michael Gramlich
Inaugural NSW AustraliaAmerican Fulbright
Commission Fellowship
German Research Foundation
$124,000
Page 24 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
20102011
Mirana Ramialison
EMBO Long Term Fellowship
HFSP Fellowship
2 yrs (1 taken)
3 yrs
$135,276
$216,900
20112014
James Chong
4yrs
$347,832
2011
Nicole Schonrock
NHMRC Postdoctoral Training
Fellowship (for study in US and
Australia)
HFSP Fellowship
2011
Henrik Reinhard
1 yr (transferred) $44,140
Danish Heart Foundation Award; 1 yr
Prince Christian Fellowship
(VCCRI)
$79,800
PRIZES AND AWARDS FOR STUDENTS AND POSTDOCTORAL FELLOWS
2011
2010
2009
2007
2007
2005
2005
2004
2002
2002
2002
2002
2002
Naisana Asli, winner Postdoctoral Poster Award, Australasian Society of
Stem Cell Research meeting, Leura, New South Wales, Australia.
Romaric Bouveret, Australian and New Zealand Society of Cell and
Developmental Biology Postdoctoral Award for Oral Presentation, 16th
Annual NSW Cell and Developmental Biology Meeting, Sydney, Australia
James Chong: finalist, Ralph Reader Prize, Cardiac Society of Australia and
New Zealand Annual Scientific Meeting, Sydney, Australia
Owen Prall (Postdoctoral Fellow): Australian and New Zealand Society for
Cell and Developmental Biology, Toshiya Yamada Postdoctoral Presentation
Prize (ComBio 2007)
Owen Prall (Postdoctoral Fellow): Runner up, Australian Museum Jamie
Callachor Eureka Prize for Medical Research
Owen Prall (Postdoctoral Fellow) Paul Korner Medal for best presentation at
the weekly seminar series at the Victor Chang Cardiac Research Institute,
Sydney
Owen Prall (Postdoctoral Fellow): Best Oral Presentation at the 15th St
Vincent’s and Mater Health Sydney Research Symposium
Edwin Kirk (PhD Student): Ralph Reader Prize (Basic Sciences Division) at
the 52nd Annual Scientific Meeting of the Cardiac Society of Australia and
New Zealand, Brisbane
Christine Biben (Postdoctoral Fellow): Paul Korner Medal for best
presentation at the weekly Paul Korner Seminar series at The Victor Chang
Cardiac Research Institute
Christine Biben (Postdoctoral Fellow): Poster Prize (Senior Research
Division) at the 12th St Vincent’s and Mater Health Sydney Research
Symposium
Thomas Yeoh (PhD Student): Ralph Reader Prize (Basic Science Division) at
the 50th Annual Scientific Meeting of the Cardiac Society of Australia and
New Zealand, Sydney
Thomas Yeoh (PhD Student), International Young Investigator’s Award
(Basic Science Division) at the XIVth meeting of the World Congress of
Cardiology, Sydney
Thomas Yeoh (PhD Student): Award for excellence (Junior Research
Division): Best Seminar at the 12th St Vincent’s and Mater Health Sydney
Research Symposium
Page 25 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
2000
Aaron Schindeler (PhD Student): Award of Excellence (Junior Research
Division): Best Seminar at the 10th St Vincent’s Health Sydney research
Symposium
Chengchun Wang (PhD Student): Paul Korner Medal for best presentation at
the weekly Paul Korner Seminar Series at The Victor Chang Cardiac Research
Institute
2000
PUBLICATIONS
Total Citations: 9033, H-Index: 49 (information gathered from Web of Science & Scopus),
Total: Peer reviewed: 99 (107); Reviews: 11; Editorials & Commentaries: 8; Edited Research
Books: 4; Book Chapters:6, Patents Applied: 8
Citations in Each Year (compiled Jan 2012)
REFEREED JOURNAL ARTICLES
1.
Crawford RJ, Krieg P, Harvey RP, Hewish DA, Wells JRE. Histone genes are
clustered with a 15-kilobase repeat in the chicken genome. Nature 1979;
279:132-36. (IF= 36.10; Citations 28)
2.
Harvey RP, Wells JRE. Isolation of a genomal clone containing chicken
histone genes. Nucleic Acids Research 1979; 7:1787-798. (IF=7.83; Citations
19)
3.
Harvey RP, Krieg PA, Robins AJ, Coles LS, Wells JRE. Non-tandem
arrangement and divergent transcription of chicken histone genes. Nature
1981; 294:49-53. (IF=36.10; Citations 15)
Page 26 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
4.
D’Andrea R, Harvey RP, Wells JRE. Vertebrate histone genes: nucleotide
sequence of a chicken H2A gene and regulatory flanking sequences. Nucleic
Acids Research 1981; 9:3119-3128. (IF=7.83; Citations 35)
5.
Harvey RP, Robins AJ, Wells JRE. Independently evolving chicken histone
H2B genes: Identification of a ubiquitous H2B-specific 5’ element. Nucleic
Acids Research 1982; 10:7851-64. (IF=7.83; Citations 123)
6.
Harvey RP, Whiting JA, Coles LS, Krieg PA, Wells JRE. H2A.F: an
extremely variant histone H2A sequence expressed in the chicken embryo.
Proceedings of the National Academy of Sciences (USA) 1983; 80:2819-23.
(IF=9.77; Citations 74)
7.
Rebagliati MR, Weeks DL, Harvey RP, Melton DA. Identification and
cloning of localised maternal RNAs from Xenopus eggs. Cell 1985; 42:769-77.
(IF=32.40; Citations 375)
8.
Harvey RP, Degryse E, Stefani L, Schamber F, Cazenave J-P, Courtney M,
Tolstoshev P, Lecocq J-P. Cloning and expression of a cDNA coding for the
anticoagulant hirudin from the bloodsucking leech, Hirudo Medicinalis.
Proceedings of the National Academy of Sciences (USA) 1986; 83:1084-88.
(IF=9.77; Citations 193)
9.
Harvey RP, Tabin CJ, Melton DA. Embryonic expression and nuclear
localization of Xenopus homeobox (Xhox) gene products. EMBO Journal
1986; 5:1237-44. (IF=10.12; Citations 121)
10.
Harvey RP, Melton DA. Microinjection of synthetic Xhox-1A homeobox
mRNA disrupts somite formation in developing Xenopus embryos. Cell 1988;
53:687-97. (IF=32.4; Citations 99)
11.
Dalton S, Robins AJ, Harvey RP, Wells JRE. Transcription from the introncontaining chicken histone H2A.F gene is not S-phase regulated. Nucleic
Acids Research 1989; 17:1745-56. (IF=7.83; Citations 26)
Page 27 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
12.
Harvey RP. The Xenopus MyoD gene: an unlocalised maternal mRNA
predates lineage- restricted expression in the early embryo. Development 1990;
108:669-80. (IF=6.89; Citations 82)
13.
Drago J, Murphy M, Carroll S, Harvey RP, Bartlett PF. Fibroblast growth
factor-mediated proliferation of central nervous system precursors depends on
endogenous production of insulin-like growth factor I. Proceedings of the
National Academy of Sciences (USA) 1991; 88:2199-203. (IF 9.77; Citations
184)
14.
Allen JD, Lints T, Jenkins NA, Copeland NG, Harvey RP, Adams JM. Novel
murine homeo box gene on chromosome 1 expressed in specific hematopoietic
lineages and during embryogenesis. Genes and Development 1991; 5:509-20.
(IF=12.88; Citations 98)
15.
Harvey RP. Widespread expression of MyoD genes in Xenopus embryos is
amplified in presumptive muscle as a delayed response to mesoderm induction.
Proceedings of the National Academy of Sciences (USA) 1991; 88:9198-202.
(IF=9.77; Citation 38)
16.
Green AR, Lints T, Visvader J, Harvey RP, Begley CG. SCL is expressed
with GATA-1 in hemopoietic cells but it also expressed in developing brain.
Oncogene 1992; 7:653-60. (IF=7.41; Citations 139)
17.
Adams JM, Houston H, Allen J, Lints T, Harvey RP. The hematopoietically
expressed vav proto-oncogene shares homology with the dbl GDP-GTP
exchange factor, the bcr gene and a yeast gene (CDC24) involved in
cytoskeletal organization. Oncogene 1992; 7:611-18. (IF=7.41; Citations 196)
18.
Harvey RP, MyoD protein expression in Xenopus embryos closely follows a
mesoderm induction-dependent amplification of MyoD transcription and is
synchronous across the future somite axis. Mechanisms of Development 1992;
37:141-49. (IF=2.95; Citations 21)
19.
Lints TJ, Parsons LM, Hartley L, Lyons I, Harvey RP. Nkx-2.5: a novel
murine homeobox gene expressed in early heart progenitor cells and their
myogenic descendants. Development 1993; 119:419-31. (IF=6.89; Citations
490)
20.
Tonissen KD, Drysdale TA, Lints TJ, Harvey RP, Krieg PA. XNkx-2.5, a
Xenopus gene related to Nkx-2.5 and tinman. Evidence for a conserved role in
cardiac development. Developmental Biology 1994; 162:325-28. (IF=4.09;
Citations 164)
21.
Copeland NG, Jenkins NA, Harvey RP. The murine homeobox genes Nkx2.3
and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics
1994; 22:655-56. (IF=3.32; Citations 9)
Page 28 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
22.
Himmelbauer H, Harvey RP, Copeland N, Jenkins N, Silver LM. High
resolution genetic analysis of a deletion on mouse chromosome 17 extending
over the fused, tufted and homeobox Nkx2-5 Loci. Mammalian Genome 1994;
5:814-16. (IF=2.77; Citation 6)
23.
Lyons I, Parsons LM, Hartley L, Li R, Andrews J, Robb L, Harvey RP.
Myogenic and morphogenetic defects in the heart tubes of murine embryos
lacking the homeobox gene Nkx2-5. Genes & Development 1995; 9:1654-66.
[Journal Cover] (IF=12.88; Citations 599)
24.
Robb L, Lyons I, Li R, Hartley L, Kontgen F, Harvey RP, Metcalf D, Begley
CG. Absence of yolk sac hematopoiesis in mice with a targeted disruption of
the scl gene. Proceedings of the National Academy of Sciences (USA) 1995;
92:7075-79. (IF=9.77; Citations 358)
25.
Hentsch B, Lyons I, Li R, Hartley L, Lints T, Adams JM, Harvey RP. Hlx
homeobox gene is essential for an inductive tissue interaction that drives
expansion of embryonic liver and gut. Genes & Development 1996; 10:70-79.
(IF=12.88; Citations 94)
26.
Lints TJ, Hartley L, Parsons LM, Harvey RP. Mesoderm-specific expression
of the divergent homeobox gene Hlx during murine embryogenesis.
Developmental Dynamics 1996; 205:457-70. (IF=2.86; Citations 29)
27.
Blackburn CC, Augustine C, Li R, Harvey RP, Malin MA, Boyd RL, Miller
JFAP, Morahan G. The nu gene acts cell-autonomously and is required for
differentiation of thymic epithelial progenitors. Proceedings of the National
Academy of Sciences (USA) 1996; 93:5742-46. (IF=9.77; Citations 86)
28.
Ross RS, Navankasattusas S, Harvey RP, Chien KR. An HF1a/HF-1b/MEF-2
combinatorial element confers cardiac ventricular specificity and establishes an
anterior-posterior gradient of expression. Development 1996; 122:1799-809.
[Journal Cover] (IF=6.89; Citations 101)
29.
Zou Y, Evans S, Chen J, Kuo H-C, Harvey RP, Chien KR. Carp, a cardiac
ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway.
Genes and Development 1997; 124:793-804. (IF=12.88; Citations 164)
30.
Biben C, Harvey RP. Homeodomain factor Nkx2-5 controls left/right
asymmetric expression of bHLH gene eHand during murine heart
development. Genes and Development 1997; 11:1357-69. [Journal Cover]
(IF=12.88; Citations 205)
31.
Biben C, Stanley E, Fabri L, Kotecha S, Rhinn M, Drinkwater C, Lah M,
Wang C-C, Nash A, Hilton D, Ang S-L, Mohun T, Harvey RP. Murine
cerberus homologue mCer-1: a candidate anterior patterning molecule.
Developmental Biology 1998; 194:135-51. (IF=4.09; Citations 131)
Page 29 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
32.
Biben C, Hatzistavrou T, Harvey RP. Expression of NK-2 class homeobox
gene Nkx2-6 In foregut endoderm and heart. Mechanisms of Development
1998; 73:125-27. (IF=2.95; Citations 34)
33.
Stanley E, Gilbert DG, Jenkins NA, Copeland NG, Harvey RP. Murine
cerberus homologue Cer1 maps to chromosome 4. Genomics 1998; 49:337-38.
(IF=3.32; Citations 5)
34.
Ranganayakulu G, Elliot DA, Harvey RP, Olsen EN. Divergent roles for Nk-2
Class homeobox genes in cardiogenesis in flies and mice. Development 1998;
125:3037-48. (IF=6.89; Citations 76)
35.
Robb L, Mifsud L, Hartley L, Biben C, Harvey RP. Epicardin: a novel basic
helix-loop-helix transcription factor gene expressed in epicardium, branchial
arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads.
Developmental Dynamics 1998; 213:105-13. (IF=2.86; Citations 49)
36.
Robb L, Wang C-C, Harvey RP, Begley G. Musculin: a murine basic helixloop-helix transcription factor gene expressed in embryonic skeletal muscle.
Mechanisms of Development 1998; 76:197-201. (IF=2.95 Citations 22)
37.
Stanley E, Biben C, Kotecha S, Fabri L, Tajbakhsh S, Wang C-C, Hatzistavrou
T, Roberts R, Drinkwater C, Lah M, Buckingham M, Hilton D, Nash A,
Mohun T, Harvey RP. DAN is a secreted glycoprotein related to Xenopus
cerberus. Mechanisms of Development 1998; 77:173-84. (IF=2.95; Citations
66)
38.
Lah M, Brodnicki T, Maccarone P, Fabri LJ, Nash A, Stanley E, Harvey RP.
Human cerberus related gene CER1 maps to chromosomes 9. Genomics 1999;
55:364-66. (IF=3.32; Citations 6)
39.
Brown S, Biben C, Ooms L, Maimone M, McGrath MJ, Gurung R, Harvey
RP, Mitchell CA. The cardiac expression of striated muscle LIM protein 1
(SLIM1) is restricted to the outflow tract of the developing heart. Journal of
Molecular and Cellular Cardiology 1999; 31:837-43. (IF=5.49; Citations 17)
40.
Reecy JM, Li X, Yamanda M, Demayo FJ, Newman CS, Harvey RP,
Schwartz RJ. Identification of upstream regulatory regions in the heartexpressed homeobox gene Nkx2-5. Development 1999; 126:839-49. (IF=6.89;
Citations 70)
41.
Robb L, Brodnicki T, Misfud L, Copeland NG, Gilbert DJ, Jenkins NA,
Harvey RP. Assignment of the human helix-loop-helix transcription factor
gene musculin/activated B-cell factor 1 (Msc) to chromosome 8q21 and its
mouse homologue (Msc) to the proximal region of chromosome 1. Genomics
1999; 57:318-19. (IF=3.32; Citations 3)
Page 30 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
42.
Semsarian C, Wu M-J, Ju Y-K, Marciniec T, Yeoh T, Allen DG, Harvey RP,
Graham RM. Skeletal muscle hypertrophy is mediated by a Ca2+ -dependent
calcineurin signalling pathway. Nature 1999; 400:576-81. (IF=36.10;
Citations 267)
43.
Woldeyesus MT, Britsch S, Riethmacher D, Xu L, Sonnenberg-Riethmacher E,
Abou-Rebyeh F, Harvey RP, Caroni P, Birchmeier C. Peripheral nervous
system defects in erbB2 mutants following genetic rescue of heart
development. Genes & Development 1999; 13:2538-48. (IF=12.88; Citation
139)
44.
Stanley EG, Biben C, Allison J, Hartley L, Wicks I, Campbell I, McKinley M,
Barnett L, Koentgen F, Robb L, Harvey RP. Targeted insertion of a lacZ
reporter gene into the mouse Cer1 locus reveals complex and dynamic
expression during embryogenesis. Genesis (Formally Developmental Genetics)
2000; 26:259-64. (IF=2.39; Citations 31)
45.
Wang C-C, Brodnicki T, Copeland NG, Jenkins NA, Harvey RP. Conserved
linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in
mammals. Mammalian Genome 2000; 11:466-68. (IF=2.77; Citations 12)
46.
Wang C-C, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F,
Tarlinton D, Harvey RP. Homeodomain factor Nkx2-3 controls regional
expression of leukocyte homing coreceptor MAdCAM-1 in specialised
endothelial cells of the viscera. Developmental Biology 2000; 224:152-67.
[Journal Cover] (IF=4.09; Citations 29)
47.
Christoffels VM, Habets PEMH, Franco D, Campione M, de Jong F, Lamers
WH, Bao Z-Z, Palmer S, Biben C, Harvey RP, Moorman AFM. Chamber
formation and morphogenesis in the developing mammalian heart.
Developmental Biology 2000; 223:266-78. [Journal Cover] (IF=4.09;
Citations 200)
48.
Bates MD, Schatzman LC, Lints T, Hamlin PE, Harvey RP, Potter SS.
Structural and functional characterisation of the mouse Hlx homeobox gene.
Mammalian Genome 2000; 11:836-42. (IF=2.77; Citations 6)
49.
Biben C, Weber R, Kesteven S, Stanley E, McDonald L, Barnett L, Konentgen
F, Robb L, Feneley M, Harvey RP. Cardiac septal and valvular
dysmorphogenesis in mice heterozygous for mutations in the homeobox gene
Nkx2-5. Circulation Research 2000; 87:888-95. (IF=9.50; Citations 124)
50.
Palmer S, Groves N, Schindeler A, Yeoh T, Biben C, Wang C-C, Sparrow DB,
Bartnett L, Jenkins NA, Copeland NG, Koentgen F, Mohun T, Harvey RP.
The small muscle-specific protein Cs1 modifies cell shape and promotes
myocyte fusion in an insulin-like growth factor 1- dependent manner. Journal
of Cell Biology 2001; 153:985-97. (IF=9.92; Citations 44)
Page 31 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
51.
Bates MD, Schatzman LC, Harvey RP, Potter SS. Two CCAAT boxes in a
novel inverted repeat motif are required for Hlx homeobox gene expression.
Biochimica et Biophysica Acta-Gene Structure and Expression 2001;
1519:96-105. (IF=4; Citations 4)
52.
Phiel CJ, Gabetta V, Parsons LM, Rothblat D, Harvey RP, McHugh KM.
Differential binding of an SRF/NK-2/MEF2 transcription factor complex in
normal versus neoplastic smooth muscle tissues. Journal of Biological
Chemistry 2001; 276:34637-650. (IF=5.32; Citations 19)
53.
Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson E, Srivastava D.
The combinatorial activities of Nkx2.5 and Dhand are essential for cardiac
ventricle formation. Developmental Biology 2001; 239:190-203. [Journal
Cover] (IF=4.09; Citations 82)
54.
Zammit DJ, Berzins SP, Gill JW, Barnett L, Koentgen F, Lambert GW,
Harvey RP, Boyd RL, Classon BJ. Essential role for the lymphostromal
plasma membrane Ly-6 superfamily molecule thymic shared antigen 1 in
development of the embryonic adrenal gland. Molecular and Cellular Biology
2002; 22:946-52. (IF=6.18; Citations 47)
55.
Stanley E, Biben C, Elefanty A, Barnett L, Koentgen F, Robb L, Harvey RP.
Efficient cre-mediated deletion in cardiac progenitor cells conferred by a
3’UTR-ires-cre allele of the homeobox gene Nkx2-5. International Journal of
Developmental Biology 2002; 46:431-39. (IF=2.85; Citations 65)
56.
Biben C, Wang C-C, Harvey RP. NK-2 class homeobox genes and
pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth
morphogenesis. International Journal of Developmental Biology 2002;
46:415-22. (IF=2.85; Citations 11)
57.
Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson
T, Ghosh S, Brynjolfsson J, Gunnarsdottir S, Ivarsson O, Chou TT, Hajaltason
O, Birgisdottir B, Jonsson H, Gudnadottir VG, Gudmundsdottir E, Bjornsson
A, Ingvarsson B, Ingason A, Sigfussion S, Hardardottir H, Harvey RP, Lai D,
Zhou M, Brunner D, Mutel V, Gonzalo A, Lemke G, Sainz J, Johannesson G,
Andresson T, Gudbjartsson D, Manolescu A, Frigge ML, Gurney ME, Kong
A, Gulcher JR, Petursson H, Stefansson K. Neuregulin 1 and susceptibility to
schizophrenia. American Journal of Human Genetics 2002; 71:877-92.
(IF=11.68; Citations 730)
58.
Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp
R, Jen K, Biben C, Runke G, Mackay J, Novotny J, Schwartz RJ, Harvey RP,
Mullins MC, Epstein JA. Hop is an unusual homeobox gene that modulates
cardiac development. Cell 2002; 110:713-23. (IF=32.40; Citations 136)
59.
Tarlinton D, Light A, Metcalf D, Li R, Harvey RP, Robb L. Architectural
defects in the spleens of Nkx2-3 deficient mice are intrinsic and associated
with defects in both B cell maturation and T cell-dependent immune responses.
Journal of Immunology 2003; 170:4002-10. (IF=5.74; Citations 21)
Page 32 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
60.
Elliott DA, Kirk E, Yeoh T, Chander S, McKenzie F, Taylor P, Grossfield P,
Fatkin D, Jones O, Hayes P, Feneley M, Harvey RP. Cardiac homeobox gene
NKX2-5 mutations and congenital heart disease: Associations with atrial septal
defect and hydroplastic left heart syndrome. Journal of the American College
of Cardiology 2003; 41:2072-76. (IF=14.29; Citations 77)
61.
Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJP, Lai D, McDonald
PA, Niederreither K, Dolle P, Bruneau BG, Zorn AM, Harvey RP. Cardiac Tbox factor Tbx20 directly interacts with Nkx2-5, GATA4 and GATA5 in
regulation of gene expression in the developing heart. Developmental Biology
2003; 262:206-24. (IF=4.09; Citations 96)
62.
Von Both I, Silvestri C, Erdemir T, Lickert H, Walls JR, Henkelman RM,
Rossant J, Harvey RP, Attisano L, Wrana JL. Foxh1 is essential for
development of the anterior heart field. Developmental Cell 2004; 7:31-345.
(IF=13.94; Citations 74)
63.
Stennard FA, Costa MW, Lai D, Biben C, Preis JI, Dunwoodie SL, Elliott DE,
Prall OWJ, Black BL, Fatkin D, Harvey RP. Murine T-box transcription
factor Tbx20 acts as a repressor during heart development, and is essential for
adult heart integrity, function and adaption. Development 2005; 132:2451-462.
(IF=6.89; Citations 75)
64.
Schindeler A, Lavulo L, Harvey RP. Muscle costameric protein, Chisel/Smpx,
associates with focal adhesion complexes and modulates cell spreading in vitro
via a Rac1/p38 pathway. Experimental Cell Research 2005; 307:367-80.
(IF=3.60; Citations 7)
65.
O’Tuathaigh CM, O’Sullivan GJ, Kinsella A, Harvey RP, Tighe O, Croke DT,
Waddington JL. Sexual dimorphism changes in the exploratory and habituation
profiles of heterozygous neuregulin-1 knockout mice. NeuroReport 2006;
17:79-83. (IF=1.82; Citations 31)
66.
Mikhalkevich N, Becknell B, Caligiuri MA, Bates MD, Harvey RP, Zheng
WP. Responsiveness of naïve CD4 T Cells to polarizing cytokines determines
the ratio of Th1 and Th2 cell differentiation. Journal of Immunology 2006;
176:1553-60. (IF=5.74; Citations 10)
67.
Elliott DA, Solloway MJ, Wise N, Biben C, Costa M, Furtado MB, Lange M,
Dunwoodie S, Harvey RP. A tyrosine-rich domain within homeodomain
transcription factor Nkx2-5 is an essential element in the early cardiac
transcriptional regulatory machinery. Development 2006; 133:1311-1322
[Journal Cover]. (IF=6.89; Citations 9)
68.
Vermont J, Garnier J-M, Dierich A, Niederreither K, Harvey RP, Chambon P,
Dolle P. Conditional (loxP-flanked) allele for the gene encoding the retinoic
acid-synthesizing enzyme retinoic acid-synthesizing enzyme (RALDH2).
Genesis 2006; 44:155-158. (IF=2.39; Citations 8)
Page 33 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
69.
Kirk EP, Hyun C, Thompson PC, Lai D, Castro ML, Biben C, Buckley MF,
Martin IC, Moran C, Harvey RP. Quantitative trait loci modifying cardiac
atrial septal morphology and risk of patent foramen ovale in the mouse.
Circulation Research 2006; 98:651-658. (IF=9.50; Citations 9)
70.
Christoffels VM, Mommersteeg MTM, Trowe M-O, Prall O, de Gier-de Vries
C, Soufan AT, Bussen M, Schuster-Gossler K, Harvey RP, Moorman AFM,
Kispert A. Formation of the venous pole of the heart from an Nkx2-5-negative
cell population requires Tbx18. Circulation Research 2006; 98:1555-1563.
(IF=9.50; Citations 64)
71.
Bates MD, Dunagan DT, Welch LC, Kaul A, Harvey RP. The H1x homeobox
transcription factor is required early in enteric nervous system development.
BMC Developmental Biology 2006; 6:33. (IF=2.78; Citations 7)
72.
Preis JI, Wise N, Solloway MJ, Harvey RP, Sparrow DB, Dunwoodie SL.
Generation of conditional Cited2 null alleles. Genesis 2006; 44:579-83.
(IF=2.39; Citations 4)
73.
Mommersteeg MTM, Hoogaars WMH, Prall OWJ, de Gier-de Vries C, Wiese
C, Papaioannou VE, Brown NA, Harvey RP, Moorman AFM, Christoffels
VM. Molecular pathway for the localized formation of the sinoatrial node.
Circulation Research 2007; 100:354-62. (IF=9.50; Citations 71)
74.
Prall OWJ, Menon MK, Solloway MJ, Watanabe Y, Zaffran S, Bajolle F,
Biben C, McBride JJ, Robertson BR, Chaulet H, Stennard FA, Wise N, Schaft
D, Wolstein O, Furtado MB, Shiratori H, Chien KR, Hamada H, Black BL,
Saga Y, Robertson EJ, Buckingham ME, Harvey RP. An Nkx25/Bmp2/Smad1 negative feedback loop orchestrates cardiac progenitor cell
specification and proliferation in the second heart field. Cell 2007; 128:947959. (IF=32.40; Citations 106)
75.
Karl T, Duffy L, Scimone A, Harvey RP, Schofield P. Altered motor activity,
exploration and anxiety in heterozygous neuregulin 1 mutant mice:
implications for understanding schizophrenia. Genes, Brain and Behaviour
2007; 6:677-87. (IF=4.06, Citations 30)
76.
O’Tuathaigh CMP, Babovic D, O’Sullivan GS, Meara GF, Clifford JJ, Tighe
O, Croke DT, Harvey RP, Waddington JL. Phenotypic characterisation of
spatial cognition and social behaviour in mice with “knockout” of
schizophrenia risk gene neuroegulin-1. Neuroscience 2007; 147:18-27.
(IF=3.21; Citations 1)
77.
Kirk EP, Sunde M, Costa MW, Rankin SA, Wolstein O, Castro MK, Butler
TL, Hyun C, Guo G, Otway R, Mackay JP, Waddell LB, Cole AD, Hayward
C, Keogh A, Macdonald P, Griffiths L, Fatkin D, Sholler GF, Zorn AM,
Feneley MP, Winlaw DS, Harvey RP. Mutations in cardiac T-box factor
TBX20 are associated with diverse cardiac pathologies, including defects of
septation and valvulogenesis, and cardiomyopathy. American Journal of
Human Genetics 2007; 81:280-291. (IF= 11.68; Citations 24)
Page 34 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
78.
Hattori K, Nakamura K, Hisatomi Y, Matsumoto S, Suzuki M, Harvey RP,
Kurihara H, Hattori S, Yamamoto T, Michalak M, Endo F. Arrhythmia
induced by spatiotemporal over- expression of calreticulin in the heart.
Molecular Genetics and Metabolism 2007; 91:285-93. (IF=3.53; Citations 9)
79.
Mommersteeg MTM, Brown NA, Prall OWJ, de Gier-de Vries C, Harvey RP,
Moorman AFM, Christoffels VM. Pitx2 and Nkx2-5 are required for the
formation and identity of the pulmonary myocardium. Circulation Research
2007, 101:902-909. (IF=9.50; Citations 60)
80.
Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M,
Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A, Mackay CR,
Mackay F. Disrupted cardiac development but normal hematopoiesis in mice
deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proceedings of the
National Academy of Sciences (USA) 2007: 104:14759-764. (IF=9.77;
Citations 48)
81.
Yadava RS, Frenzel I–I, McCardell CD, Yu Q, Srinivasan V, Tucker AL,
Puymirat J, Thorton CA, Prall OWJ, Harvey RP, Mahadevan MS. RNA
toxicity in mytonic muscular dystrophy induces NKX2-5 expression. Nature
Genetics 2008; 40:61-68. (IF=36.37; Citations 41)
82.
O’Tuathaigh CM, O’Connor AM, O’Sullivan G, Lai D, Croke DT, Harvey
RP, Waddington JL. Disruption to social dyadic interactions but not
emotional/anxiety-related behaviour in mice with heterozygous ‘knockout’ of
the schizophrenia risk gene neuregulin-1. Progress in NeuroPsychopharmacology & Biological Psychiatry 2008; 32:462-466. (IF=2.87;
Citations 36)
83.
Drenckhahn J-D, Schwarz QP, Gray S, Laskowski A, Kiriazis H, Ming Z,
Harvey RP, Du X-J, Thorburn DR, Cox TC. Compensatory growth of healthy
cardiac cells in the presence of diseased cells restores cardiac tissue
homeostasis during heart development. Developmental Cell 2008; 15:521-533
[Journal Cover] (IF=13.94; Citations 15).
84.
Furtado MB, Solloway MJ, Jones V, Costa MW, Biben C, Wolstein O, Preis
JI, Sparrow DB, Saga Y, Dunwoodie SL, Robertson EJ, Tam PPL, Harvey
RP. BMP/SMAD1 signalling sets a threshold for the left/right pathway in
lateral plate mesoderm and limits availability of SMAD4. Genes and
Development 2008; 22:3037-3049 (IF=12.88; Citations 10)
85.
Ferdous A, Caprioli A, Lacovino M, Martin CM, Morris J, Richardson JA,
Latif S, Hammer RE, Harvey RP, Olson EN, Kyba M, Garry DJ. Nkx2-5
transactivates the Ets-related protein 71 gene and specifies an
endothelial/endocardial fate in the developing embryo. Proceedings of the
National Academy of Science (USA) 2009; 106:814-819 (IF=9.77; Citations
19)
Page 35 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
86.
Xaymardan M, Cimini M, Fazel S, Weisel RD, Lu W-Y, Martin U, Harvey
RP, Li R-K. c-kit Function is Necessary For In vitro Myogenic Differentiation
Of Bone Marrow Hematopoietic Cells. Stem Cells 2009 27:1911-1920
(IF=7.87; Citation: 6)
87.
Tomiyama K, O’Tuathaigh CM, O’Sullivan GJ, Kinsella A, Lai D, Harvey
RP, Tighe O, Croke DT, Koshikawa N, Waddington JL. Phenotype of
spontaneous orofacial dyskinesia in neuregulin-1 ‘knockout’ mice. Progress in
Neuro-Psychopharmacology & Biological Psychiatry 2009; 33:330-333
(IF=2.87; Citation: 2)
88.
Chikhani S, Fernandez F, Poetter K, Toohey B, Harvey R, Griffiths LR.
Investigation Between the S377G GATA-4 Polymorphism and Migraine. The
Open Neurology Journal 2009 2:35-38. (IF=n/a; Citation: 2)
89.
Esposito G, Grutter G, Drago F, Costa MW, De Santis A, Bosco G, Marino B,
Bellacchiol E, Lepri F, Harvey RP, Sarkozy A, Dallapiccola B. Molecular
Analysis of PRKAG2, LAMP2 and NKX2-5 Genes in a Cohort of 125 Patients
with Accessory Atrioventricular Connection. American Journal of Medical
Genetics A 2009 149A: 1574-1577 (IF=2.55; Citation 7).
90.
Macindoe I, Glockner L, Vukasin P, Stennard FA, Costa MW, Harvey RP,
Mackay JP and Sunde M. Conformational stability and DNA binding
specificity of the cardiac T-box transcription factor Tbx20. Journal of
Molecular Biology 2009 389:606-618 (IF=4.00; Citation 6).
91.
Posch MG, Gramlich M, Sunde M, Schmitt K, Richter S, Perrot A, Panek AN,
Al Khatib I, Nember G, Megarbane A, Dietz R, Stiller B, Berger F, Harvey
RP, Ozcelik C. A gain-of-function TBX20 mutation causes human congenital
cardiac atrial septal and valve defects. Journal of Medical Genetics 2009 47:
230-235 (IF=7.03; Citations 8)
92.
O’Tuathaigh CMP, Harte M, O’Leary C, O’Sullivan GJ, Blau C, Lai D,
Harvey RP, Tighe O, Fagan AJ, Kerskens C, Reynolds G, Waddington JL.
Schizophrenia-related endophenotypes in heterozygous neuregulin-1
‘knockout’ mice: NMDA-receptor antagonist effects, neurochemistry and brain
structure. European Journal of Neuroscience 2010, 31:349-358 (IF=3.65;
Citation: 2)
93.
Walsh J, Tighe O, Lai D, Harvey R, Karayiorgou M, Gogos JA, Waddington
JL, O’Tuathaigh CMP. Disruption of thermal nociceptive behaviour in mice
mutant for the schizophrenia-associated genes NRG1, COMT and DISC1.
2010 Brain Research 1348:114-119 (IF=2.62; Citation: 3)
94.
Yuasa S, Onizuka T, Shimoji K, Ohno Y, Kageyama T, Yoon SH, Egashira T,
Seki T, Hashimoto H, Nishiyama T, Kaneda R, Murata M, Hattori F, Makino
S, Sano M, Ogawa S, Prall OWJ, Harvey RP, Fukuda K. Zac1 Is an Essential
Transcription Factor for Cardiac Morphogenesis. Circulation Research 2010,
106 (IF=9.50;Citation: 4)
Page 36 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
95.
Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wieelmann A,
Harriss J, Ferrazzi F, Bottger T, Harvey RP, Tucker PW, Engel FB. Cardiac
deletion of Smyd2 is dispensable for mouse heart development. PLoS ONE
2010 5(3): e97748 (IF=4.41; Citation:5)
96.
Butler TL, Esposito G, Blue GM, Cole AD, Costa MW, Waddell LB, Walizada
G, Sholler GF, Kirk EP, Harvey RP, Winlaw DS. GATA4 mutations in 357
unrelated patients with congenital heart malformation. Genetic Testing and
Molecular Biomarkers 2010, 14:797-802 (IF=0.87; Citation: 2)
97.
Lai D, Forrai A, Liu X, Wolstein O, Michalicek J, Ahmed I, Garratt AN,
Birchmeier C, Zhou M, Hartley L, Robb L, Feneley MP, Fatkin D, Harvey
RP. Neuregulin 1 sustains the gene regulatory network in both trabecular and
non-trabecular myocardium. Circulation Research 2010, 107:715-727
[journal cover] (IF=9.50; Citation: 5)
98.
Granados JT, Pope M, Eason J, Bu’lock F, Cox J, Kirk EP, Fatkin DA, Feneley
MP, Harvey RP, Armour JAL, Brook JDB. A-myosin heavy chain (MYH6)
mutations affecting myofibril formation are associated with congenital heart
defects Human Molecular Genetics 2010 in press (IF=8.05; Citation: 4)
99.
Medioni C, Bertrand N, Mesbah K, Dupays L, Wolstein O, Washkowitz AJ,
Papaiannou VE, Mohun T, Harvey RP and Zaffran S. Expression of Slit and
Robo genes in the developing mouse heart. Developmental Dynamics 2010,
239:3303-3311 (IF=2.86; Citation 1)
100.
Furtado MB, Biben C, Harvey RP. Characterization of Pitx2c expression in
the mouse heart using a reporter transgene Developmental Dynamics 2011,
240:195-203 (IF=2.86; Citation 1)
101.
Takeuchi JK, Lou X, Alexander JM, Sugizaki H, Delgado-Olguin P, Holloway
AK, Mori AD, Wylie JN, Munson C, Zhu Y, Zhou Y, Yeh R-F, Henkelman
RM, Harvey RP, Metzger D, Chambon P, Stainier DYR, Pollard KS, Scott,
IC, Bruneau BG. Chromatin Remodelling Complex Dosage Modulates
Transcription Factor Function in Heart Development. Nature
Communications, 2011, 2:187; doi: 10.1038/ncomms1187 (IF=n/a; Citation
5)
102.
Bondue A, Tannler S, Chiapparo G, Chabab S, Ramialison M, Paulissen C,
Beck B, Harvey RP, Blanpain C. Defining the earliest step of cardiovascular
progenitor specification during embryonic stem cell differentiation. Journal of
Cell Biology 2011, 192:751-765 (IF=9.92; Citation 3)
103.
Caprioli A, Koyano-Nakagawa N, Iacovino M, Shi X, Ferdous A, Harvey RP,
Kyba M, Olson E, Kyba M, Garry DJ. Nkx2-5 represses Gatal gene expression
and modulates cellular fate of cardiac progenitors during embryogenesis.
Circulation 2011; 123:1633-41. (IF=14.42)
Page 37 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
104.
Lopez Floro K, Artap ST, Preis JI, Fatkin D, Chapman G, Furtado MB,
Harvey RP, Hamada H, Sparrow DB, Dunwoodie SL. Loss of Cited2 causes
congenital heart disease by perturbing left-right patterning of the body axis.
Human Molecular Genetics 2011, 20:1097-110. (IF=8.05; Citation 1)
105.
Qian L Wythe JD, Liu J, Gartry J, Vogler G, Mohapatra B, Otway R, Hang Y,
King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C,
Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD,
Srivastava D, Ocorr K, Bruneau BG, Bodmer R. Conserved Cdc42 interaction
with tinman/Nkx2.5 via microRNA-1 in regulating heart function. Journal of
Cell Biology 2011, 193:1181-96. (IF=9.92; Citation 1)
106.
Moradi Marjaneh M, Kirk EP, Posch MG, Ozcelik C, Berger F, Hetzer R,
Otway R, Butler TL, Blue GM, Griffiths LR, Fatkin D, Martinson JJ, Winlaw
DS, Feneley MP, Harvey RP. Investigation of Association between PFO
Complicated by Cryptogenic Stroke and a Common Variant of the Cardiac
Transcription Factor GATA4. PLoS ONE 2011, 6:e20711 (IF=4.41)
107.
Esposito G, Butler TL, Blue GM, Cole AD, Sholler GF, Kirk EP, Grossfeld P,
Perryman BM, Harvey RP, Winlaw DS. Somatic mutations in NKX2-5,
GATA4 and HAND1 are not a common cause of Tetralogy of Fallot or
Hypoplastic Left Heart Syndrome. American Journal of Medical Genetics
Part A, 2011, 155:2416-1421 (IF=2.55)
108.
Grandos-Riveron JT, Pope M, Bu’Lock FA, Thornborough C, Eason J,
Setchfield K, Kirk EP, Fatkin D, Feneley, MP, Harvey RP, Brook JD.
Combined mutation screening of NKX2-5, GATA4 and TBX5 in congenital
heart disease: multiple heterozygosity and novel mutations. Congenital Heart
Disease 2011 [in press 27.07.11] (IF=n/a)
109.
Pelecanos R, Li J, Gongora M, Chandrakanthan V, Scown J, Suhaimi M,
Brooke G, Christensen ME, Doan T, Rice AM, Osborne GW, Grimmond SM,
Harvey RP, Atkinson K, Little MH. Comprehensive transcriptome and
immunophenotype analysis of renal and cardiac MSC-like populations
supports strong congruence with bone marrow MSC despite maintenance of
distinct identities. Stem Cell Research 2012, 8:58-53
[doi:10.1016/j.scr.2011.08.003] (IF=3.38; Citation 1))
110.
Costa MW, Lee S, Furtado MB, Xin L, Sparrow DB, Martinez CG,
Dunwoodie SL, Kurtenbach E, Mohun T, Rosenthal N, Harvey RP. Complex
SUMO-1 regulation of cardiac transcription factor Nkx2-5. PLoS One. 2011,
6:e24812 (IF=4.3)
111.
Chong JJH, Chandrakanthan V, Xaymardan M, Asli NS, Li J, Heffernan C,
Menon MK, Ahmed I, Scarlett CJ, Rashidianfar A, Biben C, Zoellner H,
Colvin EK, Pimander J, Biankin AV, Zhou B, Pu WT, Prall OWJ, Harvey RP.
Adult cardiac MSC-like stem cells with a pro-epicardial origin. Cell Stem Cell
2011, 9:527-540 (IF=25.94; Citation 1)
Page 38 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
Accompanied by Preview (Slukvin II, Cell Stem Cell 2011, 9:492-493 DOI
10.1016/j.stem.2011.11.010)
[Press releases from VCCRI and Cell Stem Cell; Media interviews for
Australian Associated Press (serving news outlets in Australian and
internationally), National Radio News, 2UE, ABC Radio National Health
Report (Norman Swan). Interview for an article in The Scientist magazine.
Research featured in Research Highlights in Nature 480, 7376, 2011].
112.
Koss M, Bolze A, Brendolan A, Saggese M, Capellini T, Bojilova E, Boisson
B, Prall OWJ, Elliott D, Solloway M, Hidaka C, Chang C-P, Mahlaoui N,
Harvey RP, Casanova J-L, Selleri L. Congenital Asplenia in Mice and
Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Developmental Cell [in
press 31.01.12]
113.
Moradi Marjaneh M, Kirk EP, Moran C, Martin ICA, Harvey RP, Thomson
PC. QTL Mapping of Complex Binary Traits in Advanced Intercross Line.
Animal Genetics 2012 [in press 25.01.12]
114.
Yang J, Bucker S, Jungblut B, Bottger T, Cinnamon Y, Tchorz J, Muller M,
Bettler B, Harvey RP, Sun Q-Y, Schneider A, Braun T. Inhibition of Notch2
by Numb/Numblike controls myocardial compaction in the heart. [Submitted,
Development 070112]
115.
Castagnaro L, Maruzzelli S, Lenti E, Spinardi L, Sitia G, Harrelson Z, Guidotti
LG, Evans S, Harvey RP, Brendolan A. Nkx2-5/Islet1+ spleen mesenchymal
progenitors generate different stromal cell lineages and participate in organ
regeneration. [submitted Nature Immunology Jan 2012]
116.
Nakano H, Arshi A, Shin J-H, Liu X, van Handel B, Sasidharan R, Harmon
AW, Nakashima Y, Schwartz RJ, Conway SJ, Harvey RP, Pashmforoush M,
Mikkola HKA, Nakano A. Hemogenic activity of the endocardium is
dependent on Nkx2.5 [in preparation]
117.
Lee LK, Bryant KJ, Bouveret R, Lei P-W, Duff AP, Harrop SJ, Huang EP,
Harvey RP, Gelb MH, Gray PP, Curmi PM, Cunningham AM, Church WB,
Scott KF. A role for vimentin in regulation of arachidonic acid metabolism
revealed by structure function studies of human group IIA secreted
phospholipase A2 and its inhibitors. [submitted Molecular Cell 231211]
118.
Wong SYY, Zhang JCL, Leung AWL, Leung KKH, Dung N, Shang C, Prall
OWJ, Pu WT, Chan D, Mohun TJ, Harvey RP, Tam PPL, Cheah KSE.
Procollagen IIA modulates BMP control of early cardiogenesis via an Nkx2-5
positive regulatory loop [in preparation].
119.
Behrens AN, Iacovino M, Lohr JL, Ren Y, Kyba M, Harvey RP, Garry D,
Martin CM. Nkx2-5 mediates differential differentiation through and
interaction with Hox10 [in preparation]
Page 39 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
120.
Guo G, Costa MW, Otway R, Castro ML, Baddeley O, Crotty H, Yeoh T, Riek
P, Cochrane N, Semsarian C, Weintraub RG, Haywood C, Keogh A,
McDonald P, Harvey RP, Fatkin D. Phenotypic spectrum of mutations in the
cardiac transcription factor, NKX2.5, includes adult-onset dilated
cardiomyopathy with conduction-system disease [In preparation].
Page 40 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
REVIEWS
1.
Balland A, Courtney M, Jallet S, Tessier L, Sondermeyer P, de la Salle H,
Harvey RP, Degryse E, Tolsteshev P. Use of synthetic oligonucleotides in gene
isolation and manipulation. Biochimie 1985; 67:725-36. (IF=3.07; Citations 4)
2.
Harvey RP. What regulates the cell cycle? Today’s Life Sciences 1990; 2:28-34.
3.
Harvey RP. NK-2 homeobox genes and heart development. Developmental
Biology 1996; 178:203-16. [Journal Cover] (IF=4.37; Citations 346)
4.
Harvey RP. Cardiac looping - an uneasy deal with laterality. Seminars in Cell &
Developmental Biology 1998; 9:101-08. (IF=6.34; Citations 24)
5.
Harvey RP. Links in the left/right axial pathway. Cell 1998; 94:273-76.
(IF=31.15; Citations 101)
6.
Harvey RP. Seeking a regulatory roadmap for heart morphogenesis. Seminars in
Cell & Developmental Biology 1999; 10:99-107. (IF=6.34; Citations 23)
7.
Prall OWJ, Elliott D, Harvey RP. Developmental paradigms in heart disease:
Insights from Tinman. Annals of Medicine 2002; 34:148-56. (IF=4.63;
Citations 25)
8.
Harvey RP. Patterning the vertebrate heart. Nature Reviews Genetics 2002;
3:544-56. (IF=27.82; Citations 119)
9.
Solloway MJ, Harvey RP. Molecular pathway in myocardial development: a
stem cell perspective. Cardiovascular Research 2003; 58:264-77. (IF=5.80;
Citations 36)
10.
Kovacic JC, Muller DWM, Harvey RP, Graham RM. Update on the use of stem
cells for cardiac disease. Internal Medicine Journal 2005; 35:348-56. (IF=1.78)
11.
Stennard F, Harvey RP. T-box transcription factor and their roles in regulatory
hierarchies in the developing heart. Development 2005; 132:4897-910. (IF=7.19;
Citations 21)
RESEARCH BOOKS
1.
Harvey RP, Olsen EN, Schultz RA, Altman J (Eds). Genetic control of heart
development: proceedings of the human frontiers science program workshop
III, Strasbourg, France, HFSP, Strasbourg 1997.
2.
Harvey RP, Rosenthal N (Eds). Heart Development. Academic Press, San Diego
1999. [~1,684 copies sold]
3.
Larson WJ (Harvey RP contributing Ed), Human Embryology (Fourth
Edition), Churchill Livingstone Inc., New York. 2008
Page 41 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
4.
Harvey RP and Rosenthal N (Eds). Heart Development and Regeneration.
Academic Press, San Diego, 2010
BOOK AND MEETING REVIEWS
1.
Harvey RP. Heart Matters. Cell 2001 107:276-77. (IF=31.15)
2.
Kovacic JC, Harvey RP, Dimmeler S. Cardiovascular Regenerative Medicine:
digging in for the long haul - meeting report, cardiovascular regenerative
medicine symposium, NIH-NHLBI, Bethesda, USA, October 1-2-2007. Cell
Stem Cell 2008; 1:628-633 (IF =23.56)
BOOK CHAPTERS
1.
Harvey RP, Wells JRE. Chicken histone genes and their variants. In: Histone
genes and histone gene expression. Stein G, Stein J (Eds). John Wiley and Son,
New York 1984; pp 245-62.
2.
Wells JRE, Coles LS, D’Andrea R, Harvey RP, Krief PA, Robins AJ, Whiting
JA. Chicken histone genes: analysis of core, H1, H5 and variant sequences. In:
Manipulation and expression of genes in eukaryotes. In: Manipulation and
expression of genes in eukaryotes. Neagly P, Linnane AW, Peacock WJ,
Pateman JA (Eds). Academic Press, Sydney 1985.
3.
Harvey RP, Biben C, Elliott D. Transcriptional control and pattern formation in
the developing vertebrate heart: studies on NK-2 class Homeodomain factors. In:
Heart Development. Harvey RP, Rosenthal N (Eds). Academic press, San Diego
1999
4.
Harvey RP. Molecular determinants of cardiac development and congenital
disease. In: Mouse Development: Patterning, Morphogenesis and
Organogenesis. Rossant J and Tam P (Eds). Academic Press, San Diego 2002;
pp331-370.
5.
Kelly RG, Harvey RP. Cardiomyogenic Precursor Cells in the Mammalian
Embryo: Induction, Hysterogeneity and morphogenesis. In Handbook of Stem
Cells. Lanza RP, Gearhart JD, Hogan BLM, Melton DA, Pederson R, Thomson
JA, West MD (Eds). Academic Press, San Diego, 2004
6.
Elliott DA, Kirk EP, Schaft D. Harvey RP. NK-2 Class Homeodomain Proteins:
Conserved Regulators of Cardiogenesis. In Heart Development and
Regeneration, Rosenthal N, Harvey RP (Eds). Academic Press, Boston, 2010
Page 42 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
CONFERENCE PAPERS
1.
Weeks DL, Rebagliati MR, Harvey RP, Melton DA. Localised maternal mRNAs
on xenopus laevis eggs. Cold Spring Harbor Symposium Quantitative Biology
1985; 50:21-30.
2.
Engelmann GL, Worrell RA, Duff RA, Grutkoski PS, Harvey RP. Expression of
cardiac muscle markers in rat myocyte cell lines. Molecular Cellular
Biochemistry 1996; 157:87-91.
3.
Harvey RP. Nkx2.5 controls Myogenesis and morphogenesis in the developing
mammalian heart. In: Genetic Control of Heart Development. Harvey RP,
Schultz R, Olson E, Altman J (Eds). HFSP, Strasbourg 1997.
4.
Biben C, Palmer S, Elliot DA, Harvey RP. Homeobox genes and heart
development. In: Cold Spring Harbor Symposia on Quantitative Biology,
Pattern Formation During Development, Vol. 62, Cold Spring Harbor
Laboratory Press, Cold Spring Harbour, NY 1997
5.
Harvey RP, Lai D, Elliott D, Biben C, Solloway M, Prall O, Stennard F,
Schindeler A, Groves N, Lavulo L, Hyun C, Yeoh T, Costa M, Furtado M and
Kirk E, Homeodomain factor Nkx2-5 in heart development and disease. In Cold
Spring Harbor Symposium on Quantitative Biology. Volume 67, Cold Springs
Harbor Laboratory Press, Cold Springs Harbor, 2002.
COMMENTARIES AND EDITORIALS
1
Rosenthal N, Harvey RP. Single allele mutations at the heart of congenital
disease. Journal of Clinical Investigation 1999; 104:1483-84. (IF=15.38;
Citations 4)
2.
Winlaw DS, Sholler GF, Harvey RP. Progress and challenges in the genetics of
congenital heart disease, Medical Journal of Australia 2005; 182:100-101.
(IF=2.89; Citations 4)
3.
Elliott DA, Harvey RP. “Time to mend a broken heart”. Stem Cell Research
2007; 1:4-6 (IF=3.36)
4.
Trounsen A, Harvey RP. “A critical time for stem cell research in Australia”
Cell Stem Cell 2008; 2:1-5 (IF=23.56)
5.
Grossfeld P, Maoqing Y, Harvey RP. “Hypoplastic left heart syndrome: New
genetic insights”. Journal of the American College of Cardiology 2009,
53:1072-1074 (IF=12.53)
6.
Harvey RP, Meilhac SM, Buckingham ME. “Landmarks and lineages in the
developing heart” Circulation Research 2009, 104:1235-1237 (IF=9.21,
Citations 1)
Page 43 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
7.
Harvey RP “Heart redevelopment” Nature (News and Views) 2010, 467:39-40
(IF=34.48)
8.
Graham RM, Harvey RP. “The Ontogeny of Cardiac Regeneration” Circulation
Research 2011, 108:1304-5 (IF=9.21)
PATENTS
1.
Vectors, transformed cells and processes for preparation of hirudin Tolstoshev P,
Harvey RP, Courtney M, LeCocq J-P. International Application
PCT/FR85/00062 (WO/ 1985/004418), (Filed 27.3.85). (USA patent 5824505)
Granted 06.01.98 (5,702.355). Part of a package of hirudin patents filed by
Transgene SA (France) subsequently sold to Bohringwerke (now Aventis) in
1995. Currently held by Schering Aktiengesellschaft. Current Status: Active
2.
Hirudin, pharmaceutical compositions comprising it and the use Tolstoshev P,
Harvey RP, Courtney M, LeCocq J-P. Divisional of international patent
application PCT/FR85/00062 (WO/1985/004418) (Filed 27.03.85). Granted
6.1.98 (5,824.505). Part of package of hirudin patents filed by Transgene SA
(France) subsequently sold to Bohringwerke (now Aventis). Currently held by
Schering Aktiengesellschaft.
Current Status: Active.
(The Above 2 patents cover the cloning of the hirudin gene from the
medicinal leech Hirudo medicinalis and expression of active recombinant
protein. Hirudin encodes a potent antithrombin anticoagulant taken to
phase III clinical trials by Ciba Geigy and found to be highly efficacious,
comparable to existing low MW heparins).
3.
Novel molecules and uses thereof (DAN/CER) Biben C, Fabri L, Harvey RP,
Hilton DJ, Lah M, Nash A and Stanley E. International patent application
PCT/AU98/00078 (W/O1998/034951) (Filed 11.02.98), USA application (filed
09/022115 Lapsed) (W/O 1998/034951), Australia application (filed 58486/98).
Status: Patent covers the production – AU Patent number: 741708 held by Amrad
operations.
Current Status: Lapsed
(This patent covers the production and use of Dan and Cerl, novel
mammalian members of the TGF superfamily)
4.
Novel molecules and methods relating thereto (Epicardin) Robb L, Harvey RP,
Begley CG. International Patent no 61/078796 lodged USA, 20.3.98. Current
Status: Lapsed
5.
Novel regulatory molecules expressed during muscle development and genetic
sequences encoding same (musculin) Robb L, Begley CG, Harvey RP.
International Application PCT/AU99/00220 (Filed 30.7.1999). Australia
Application 51408/99 (filed 30.07.1999); USA Application 09/744778 (filed
30.7.1999) Current Status: Lapsed
Page 44 of 45
Curriculum Vitae – Prof Richard P Harvey PhD, FAA
(This patent covers the novel muscle-specific transcription factor gene
musculin and regulatory sequences)
6.
Novel therapeutic molecules and uses thereof Harvey RP, Palmer S, Rosenthal
N, Musaro N. Provisional application (PP2634/98) submitted 27.3.98.
International Application PCT/AU99/00220 (Lodged 26.3.99). Australia
application 31277/99 (filed 26.9.2000); European application 99912974.5 (filed
26.9.2000); New Zealand application 507315 (filed 5.8.2000); USA application
(filed 26.9.2000). Divisional of Australian patent application 31277/99 (filed
13.5.03). Current Status: Lapsed
(This Patent covers the novel muscle-specific protein Chisel which may
function in muscle adaptive and/or stress pathways).
7.
Cell differentiation and self-renewal Harvey RP and Yeoh T. Provisional patent
filed 2.5.02 in the name of The Victor Chang Cardiac Research Institute. PCT
lodged 2.5.03 (PCT/AU03/00518). Current Status: Lapsed
(This Patent covers a novel method for modulation of muscle stem cell selfrenewal using inhibitors of p38 mitogen activated protein kinases).
8.
Novel genetic screen Harvey RP, Hyun C, Kirk EPE, Feneley MP. US
provisional patent application filed February 23rd 2004 in the name of Victor
Chang Cardiac Research Institute. International PCT Application filed February
23rd 2005 (PCT/AU2005/000231).
Current Status: Lapsed.
(This Patent covers a screen for a genetic risk factor in stroke).
Page 45 of 45