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5th year questions Q1. What are the pathological findings of a patient with APSGN? Q2. Discuss the treatment of patients with hemolytic uremic syndrome? Q3. What is the pathology of mesangial proliferation of idiopathic nephrotic syndrome? Q4. What is the pathology of focal segmental glomerulosclerosis of idiopathic nephrotic syndrome? Q5. Why patients with nephrotic syndrome are more prone for infections during relapse? What are your measures to decrease that complications? Q6. What are the risk factors for urinary tract infections? Q7. Discuss the ways of obtaining urine sample for urine cultures? Q8. What are the indications of prophylaxis in patients with urinary tract infection? Q9. What are the pathogenesis of HUS ? Q10. What is the pathology of minimal changes idiopathic nephrotic syndrome? Q11. Discus the imaginings study in patients with UTI ? MCQ 5th year Q1. Clinical pyelonephritis may be diagnosed with a positive urine culture and which of the followings: A. Urgency B. Flank pain C. Fever D. Vomiting E. Any of B, C, or D Q2.Cystitis is associated with all of the following except: A. B. C. D. E. Urgency Adenovirus Fever Absence of renal scarring Sexual activity in female Q3. Risk factors for UTI include all of the following except: A. B. C. D. E. Uncircumcised male Sexual activity Reflux nephropathy Breast feeding Spinabifida Q4. Nephritis with low C3 include all of the following except: A. Endocarditis B. SLE C. Chronic infection D. Membrano proliferative E. IgA nephropathy Q6. In treatment of UTI all are true except: A. Five days course of broad spectrum antibiotic is preferable. B. Children who are dehydrated or in whom sepsis is suspected should be admitted. C. Percutaneus drainage in children with perirenal abscess. D. A urine culture should be obtained 1 week after termination of treatment. E. Follow up urine culture should be for 1-2 years. Q7. Risk factors for UTI include all of the following except: A. B. C. D. E. Constipation Male sex Vesicouretral reflux Labial adhesion Tight clothing Q8. Indications of prophylaxis in UTI include all of the following except: A. B. C. D. E. Recurrence of UTI Neurogenic bladder Male with febrile UTI Vesicouretral reflux Urinary tract obstructions and calculi Q9. In acute hemorrhagic cystitis all are true except: A. B. C. D. E. Caused by E. Coli Caused by adenovirus 11 More frequent in females Caused by adenovirus 21 Not need treatment Q10. Cyclophosphamide in nephrotic syndrome, all are true except: A. Prolongs the duration of remission B. Reduces the number of relapses in frequently relapsing and steroid resistant nephrotic syndrome C. Is given as a single oral dose for a total duration 8-12 weeks D. Alternate day prednisone therapy is often continue with Cyclophosphamide E. Hemorrhagic cystitis is the more frequent complications Q11. In nephrotic syndrome, all true except: A. B. C. D. E. S. albumin is less than 2g/dl S. cholesterol and triglyceride are elevated S. calcium is increase Heavy proteinuria Microscopic hematuria may be present in 20% Q12. A 5-yr-old girl presents with cola-colored urine, oliguria, and body edema 2 wk after being treated for group A -hemolytic streptococcal pharyngitis. Her complement C3 is noted to be very low at 15 mg/dL. When should this patient's complement C3 level be repeated in order to confirm your suspected diagnosis? A. In 6 week B. In 2 wk C. In 3 wk D. In 4 wk E. In 8 wk Q13. All of the following statements regarding poststreptococcal glomerulonephritis (PSGN) are true except: A.PSGN is common in children 2-5 yr of age B. The acute phase of PSGN usually resolves in 6-8 wk C. Microscopic hematuria may persist for 1-2 yr following the initial presentation of PSGN D. The serum C3 level is usually reduced in the acute phase of PSGN E. The best single antibody titer to document cutaneous streptococcal infection is the deoxyribonuclease (DNase) B antigen Q14. All of the following statements about hemolytic-uremic syndrome (HUS) are true except: A.HUS is the most common cause of acute renal failure in young children B. Verotoxin elaborated by Escherichia coli O157:H7 initiates endothelial cell injury in HUS C. HUS always presents after enteritis with diarrhea D. The diagnosis of HUS requires microangiopathi hemolytic anemia, thrombocytopenia, and acute renal failure E. Mortality from HUS is less than 10 Q15. A 3-yr-old boy presents with periorbital and pedal edema. The differential diagnosis includes all of the following except: A.Protein-losing enteropathy B. Acute glomerulonephritis C. Nephrotic syndrome D. Hepatic failure E. Orthostatic proteinuria 1.E 2.C 3.D 4.E 6.A 7.B 8.C 9.C 10.B 11.C 12.E 13.A 14.C 15.E