Download Chapter 15: Chromosomal Basis of Inheritance

AP Biology II
Chapter 15 Outline
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Who was Thomas Hunt Morgan?
What is the chromosome theory of inheritance?
Why are Drosophila melanogaster good to use to study?
What does the “+” refer to when studying flies?
What are sex-linked genes and how were they discovered?
What are linked genes and how were they tested?
How does recombination occur?
How can we calculate recombination frequency?
What is a gene map? linkage map?
What was Alfred Surtevant’s contribution to Morgan’s study?
What is the chromosomal basis of gender?
How are sex linked traits distinct from autosomal?
Why do males suffer more from sex-linked disorders?
How many X’s are expressed in human females?
What is X-inactivation?
Define these terms:
a. nondisjunction
b. aneuploidy
c. polyploidy
Describe:
a. Down’s syndrome
b. Klinefelter’s syndrome
c. Turner’s syndrome
d. Fragile X syndrome
What are:
a. deletion
b. duplication
c. inversion
d. reciprocal translocations
What is genomic imprinting?
What are karyotypes?