Download Angelo Lombardo, Ph.D. – Curriculum Vitae

Angelo Lombardo, Ph.D. – Curriculum Vitae
PERSONAL INFORMATION
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Angelo Lombardo, Ph.D.
Group Leader - San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
Assistant Professor - Vita-Salute San Raffaele University (UniSR), Milan, IT
[email protected]
+39 02 2643 5680
November the 10th 1976, Turin, IT
EDUCATION
2004-2011
Ph.D. in Molecular and Cellular Biology; The Open University (Milton Keynes, UK) and
UniSR
1997-2002
M.Sc. in Biotechnology, "Summa Cum Laude" 110/110; University of Turin (IT).
EMPLOYMENT AND EXPERIENCE
Since 2015
Since 2013
Since 2011
2004-11
2002-04
2000-02
Group Leader at the SR-Tiget.
Assistant professor at UniSR.
Project Leader at the SR-Tiget.
Ph.D. Student in Cellular and Molecular Biology.
Postgraduate research fellow in the Department of Oncological Sciences, University of
Turin.
Undergraduate student in the Department of Oncological Sciences, University of Turin.
SCIENTIFIC ACTIVITY
• Author on 23 peer-reviewed articles in international scientific journals, including Cell, Nature, Nature
Biotechnology, Nature Medicine, Nature Methods and Blood; cumulative IF: 367.9 (218.3 as first or
last author); total number of citations: 2225 (1128 as first or last author); h-index: 18.
• Membership: American and European Society of Gene and Cell Therapy (ASGCT and ESGCT,
respectively), International Society for Stem Cell Research (ISSCR).
• Ad hoc reviewer for granting agencies and for the journals Molecular Therapy, Nature
Biotechnology, Epigenetics & Chromatin and Stem Cell Reports. Abstract reviewer for the ASGCT,
ESGCT and ISSCR.
HONORS
Young Investigator Award (ESGCT 2011).
Excellence in Research Award (ASGCT 2006).
Best Abstract Award (ESGCT 2009).
Premio di Ricerca & Internazionalizzazione Ricercatissimi (Lombardy region 2008).
Travel Award recipient (n.12) from the ISSCR, the ESGCT and the ASGCT.
Patents n.5 (2 granted and 3 pending)
Oral presentations at international meetings (Peer-reviewed abstracts: n. 19; invited speaker: n. 16,
including two at the Keystone Symposium on Molecular Biology, two at the ISSCR (plenary), two at
the ESGCT (plenary), ASGCT, Congresso nazionale della Società Italiana di Genetica Umana
(SIGU; plenary), Associazione di Biologia Cellulare e Differenziamento (ABCD; plenary), European
Calcified Tissue Society (ECTS; plenary), European Society for Blood and Marrow Transplantation
(EBMT) and European Society for Organ Transplantation (ESOT; plenary).
• Current funding: Italian Telethon Foundation and Italian ministry of Health.
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RESEARCH ACTIVITIES
My lab is interested in developing innovative approaches to study fundamental biological questions and
to treat diseases. In the last years, we have developed a novel strategy based on targeted epigenetic
editing to permanently silence gene expression (Amabile et al., Cell 2016). We are further extending
these studies to: (i) tackle inherited diseases, such as the hemoglobinopathies and the familiar form of
the hypercholesterolemia; (ii) shed light into the basic processes that govern establishment and
maintenance of epigenetic repression during development and cell differentiation. Furthermore, based
on our previous experience (Genovese et al., Nature 2014) we have developed state-of-the-art gene
editing strategies and coupled them with cell reprogramming to devise universally allogeneic
transplantable cells.