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Transcript
Chapter 16
Nutrition in Metabolic &
Respiratory Stress
© 2007 Thomson - Wadsworth
Body’s Response to
Stress & Injury
• Stress response
 Infection
 Burns
 Fractures
 Surgery
 Extensive bleeding
• Body focuses on
immediate survival
• Nutrients are
mobilized from
storage
• Heart rate and
respiration
increase
• Blood pressure
rises
© 2007 Thomson - Wadsworth
Hormonal Response to Stress
• Epinephrine &
norepinephrine
• Cortisol
 Enhances protein
degradation
 Stimulate heart
muscle
• Aldosterone &
 Alter blood flow rate
antidiuretic hormone
 Raise basal
 Help maintain blood
metabolism
volume
• Glucagon
 Stimulate kidneys to
reabsorb sodium &
 Releases nutrients
water
from storage
© 2007 Thomson - Wadsworth
The Inflammatory Response
• Serves to
• Classic signs
 Contain & destroy
infectious agents
 Prevent further
tissue damage
• Dilation of arterioles
• Constriction of
venules
 Swelling
 Redness
 Heat
 Pain
© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
Nutrition Treatment
• Problems
• Diet goals
 Hypermetabolism &
negative nitrogen
balance
• Wasting
 Hyperglycemia &
insulin resistance
• Increases infection risk
 Preserve lean tissues
 Maintain immune
defenses
 Promote healing
• Need to balance
overfeeding &
underfeeding
© 2007 Thomson - Wadsworth
Estimating Requirements
• Energy
 Harris-Benedict
equation (BEE)
• Protein
 1.0-2.0 g/kg
• Carbohydrates:
70% of kcalories
• Lipids: 40% of
kcalories
• Vitamins &
minerals
 May have
increased needs
© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
Approaches to Nutrition Care
• Initial care: maintain fluid &
electrolyte balance
• May need enteral and/or
parenteral support
• High-kcalorie, high-protein diet
Take care not to overfeed
Reassess frequently
© 2007 Thomson - Wadsworth
Nutrition & Respiratory Stress
• Respiratory stress
Reduced oxygen
Increased carbon
dioxide
• Labored breathing
Interferes with food
intake
Weight loss &
malnutrition
© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
Chronic Obstructive
Pulmonary Disease (COPD)
© 2007 Thomson - Wadsworth
Chronic Obstructive
Pulmonary Disease (COPD)
• Persistent obstruction
of airflow
 Chronic bronchitis
• Excessive mucus
secretions
• Productive cough
 Emphysema
• Breakdown of lung’s
elastic structure
• Dyspnea
• Causes
 Smoking
 Chronic respiratory
infections
 Occupational exposure to
dusts or chemicals
 Genetic susceptibility
• Goals




Improve food intake
Maintain healthy weight
Prevent muscle loss
Improve exercise
endurance
© 2007 Thomson - Wadsworth
Treatment
• Small, frequent
meals
• Adequate fluids
• Liquid supplements
• Exercise plan
© 2007 Thomson - Wadsworth
Respiratory Failure
• Gas exchange
between air & blood
is greatly impaired
• Consequences
 Hypoxemia
 Hypercapnia
 Hypoxia
 Acidosis
 Cyanosis
• Causes
 Obstruction
 Weakness or
paralysis of muscles
 Embolus
 Toxic substances
 Severe trauma &
infection
© 2007 Thomson - Wadsworth
Treatment
• Support lung function
• Correct underlying disorder
• Careful monitoring of fluid
• Medications
© 2007 Thomson - Wadsworth
Treatment
• Chronic lung disease
Oxygen therapy
• Acute respiratory
distress syndrome
(ARDS)
Mechanical ventilation
© 2007 Thomson - Wadsworth
Nutrition Care
• Individualize according to
patient’s condition
• Enough energy & protein to
support lung function
without overtaxing the
respiratory system
© 2007 Thomson - Wadsworth
Nutrition in Practice
Multiple Organ Failure
© 2007 Thomson - Wadsworth
Multiple Organ Failure
• Cause of death in ½
of ICU patients
• A failure of two or
more organ systems
• Chemical mediators
can cause systematic
response syndrome
(SIRS), leading to
shock & organ failure
• Organs




Lungs
Liver
Kidneys
GI tract
• Causes
 Acute respiratory
failure
 Trauma
 Sepsis
 Burns
 Extensive surgery
 Pancreatitis
© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
Risk Factors
• Age over 55
• Prior chronic
illness
• Persistent SIRS
• Major infection
• Blood
transfusions
• Severity of tissue
injury
• Length of time
between injury &
arrival at hospital
• Malnutrition
© 2007 Thomson - Wadsworth
Treatment
• Mechanical
ventilation
• Fluid &
electrolytes
• Medications to
sustain or
increase cardiac
output & blood
pressure
• Hemofiltration or
dialysis
• Antibiotic therapy
for infection
• Enteral &
parenteral
nutrition
© 2007 Thomson - Wadsworth