Download Table S1.

Gene Symbol
Gene Name
Amino Acid Metabolism
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
BCAT1
branched chain aminotransferase 1, cytosolic
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
CTH
cystathionase (cystathionine gamma-lyase)
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
KYNU
kynureninase (L-kynurenine hydrolase)
Carbohydrate Metabolism
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
ALDOB
aldolase B, fructose-bisphosphate
ALDOC
aldolase C, fructose-bisphosphate
ENO1
enolase 1, (alpha)
ENO3
enolase 3 (beta, muscle)
FBP1
fructose-1,6-bisphosphatase 1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
GBA
glucosidase, beta, acid
GYS1
glycogen synthase 1 (muscle)
HK1
hexokinase 1
LDHA
lactate dehydrogenase A
PC
pyruvate carboxylase
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PFKM
phosphofructokinase, muscle
PGAM1
phosphoglycerate mutase 1 (brain)
PGK1
phosphoglycerate kinase 1
PGM1
phosphoglucomutase 1
PKM2
pyruvate kinase, muscle
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
TPI1
triosephosphate isomerase 1
Cell Differentiation
CES1
carboxylesterase 1 (monocyte/macrophage serine esterase 1)
FSTL1
follistatin-like 1
INHBB
inhibin, beta B
MEST
mesoderm specific transcript homolog (mouse)
PEX11A
peroxisomal biogenesis factor 11 alpha
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
SFRP2
secreted frizzled-related protein 2
Cell Proliferation
ANG
angiogenin, ribonuclease, RNase A family, 5
CCND1
cyclin D1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DNASE2
deoxyribonuclease II, lysosomal
FGF2
fibroblast growth factor 2 (basic)
GHR
growth hormone receptor
IGF1
insulin-like growth factor 1 (somatomedin C)
IRS1
insulin receptor substrate 1
IRS2
insulin receptor substrate 2
Biological Function
amino acid catabolism
amino acid catabolism
amino acid catabolism
amino acid synthesis
amino acid synthesis
amino acid synthesis
amino acid catabolism
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
glycolipid metabolism
glycogenesis
aerobic glycolysis
anaerobic glycolysis
gluconeogenesis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
aerobic glycolysis
glucose transport
aerobic glycolysis
adipogenesis
cell differenciation
energy balance
adipogenesis
peroxysome organization
cell differenciation
adipogenesis
angiogenesis
cell cycle
cell cycle
cell cycle
apoptosis
cell cycle
lipolysis
glycogen synthesis
insulin signaling
insulin signaling
MAPK3
PRKAR2B
VEGFA
Cell Structure
ARPC1A
CFL1
GIT2
SNTB2
mitogen-activated protein kinase 3
protein kinase, cAMP-dependent, regulatory, type II, beta
vascular endothelial growth factor A
actin related protein 2/3 complex, subunit 1A, 41kDa
cofilin 1 (non-muscle)
G protein-coupled receptor kinase interacting ArfGAP 2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic
component 2)
SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
TUBA1A
tubulin, alpha 1a
TPM3
tropomyosin 3
WDR1
WD repeat domain 1
Energy Metabolism
ADHFE1
alcohol dehydrogenase, iron containing, 1
AK2
adenylate kinase 2
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1,
cardiac muscle
ATP8A1
ATPase, aminophospholipid transporter, class I, type 8A, member 1
CKB
creatine kinase, brain
COX7C
cytochrome c oxidase subunit VIIc
CYCS
cytochrome c, somatic
ETFA
electron-transfer-flavoprotein, alpha polypeptide
ETFDH
electron-transferring-flavoprotein dehydrogenase
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
LEP
leptin
MDH2
malate dehydrogenase 2, NAD (mitochondrial)
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
NDUFA9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NDUFB8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
UCN
Urocortin
UQCRC2
ubiquinol-cytochrome c reductase core protein II
Immune Response
C1QA
complement component 1, q subcomponent, A chain
C1QB
complement component 1, q subcomponent, B chain
C1QC
complement component 1, q subcomponent, C chain
C2
complement component 2
C3AR1
complement component 3a receptor 1
CCL18
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19
chemokine (C-C motif) ligand 19
CCL2
chemokine (C-C motif) ligand 2
CCL3
chemokine (C-C motif) ligand 3
CCR1
chemokine (C-C motif) receptor 1
CD14
CD14 molecule
CD163
CD163 molecule
CD163L1
CD163 molecule-like 1
CD209
CD209 molecule
CD48
CD48 molecule
CD53
CD53 molecule
CD68
CD68 molecule
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
CD9
CD9 molecule
cell cycle
signal transduction
angiogenesis
cytoskeleton organization
cytoskeleton organization
cytoskeleton organization
cytoskeleton organization
cytoskeleton organization
cytoskeleton organization
cytoskeleton organization
cytoskeleton organization
ketone metabolism
oxydative phosphorylation
oxydative phosphorylation
oxydative phosphorylation
creatin phosphate shuttle
oxydative phosphorylation
oxydative phosphorylation
fatty acid oxidation
fatty acid oxidation
creatin biosynthesis
tricarboxylic acid cycle
food intake control
tricarboxylic acid cycle
tricarboxylic acid cycle
oxydative phosphorylation
oxydative phosphorylation
corticoids metabolism
oxydative phosphorylation
complement system
complement system
complement system
complement system
complement system
chemotaxis
immune response
chemotaxis
chemotaxis
immune response
response to LPS
acute phase response
scavenger receptor activity
cell adhesion
Ig mediated immune response
cell adhesion
scavenger receptor activity
antigen presentation
immune response
CD97
CLEC10A
CSF1R
FCER1G
FCGBP
FCGR2B
FCGRT
FN1
FTH1
FTL
HLA-A
HMOX1
HP
IFI30
IL10
IL10RA
IL1RN
IL4R
ITGB2
ITGB5
ITGAM
ITGAX
KIT
LCP
LILRA6
CD97 molecule
C-type lectin domain family 10, member A
colony stimulating factor 1 receptor
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Fc fragment of IgG binding protein
Fc fragment of IgG, low affinity IIb, receptor (CD32)
Fc fragment of IgG, receptor, transporter, alpha
fibronectin 1
ferritin, heavy polypeptide 1
ferritin, light polypeptide
major histocompatibility complex, class I, A
heme oxygenase (decycling) 1
haptoglobin
interferon, gamma-inducible protein 30
interleukin 10
interleukin 10 receptor, alpha
interleukin 1 receptor antagonist
interleukin 4 receptor
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
integrin, beta 5
integrin, alpha M (complement component 3 receptor 3 subunit)
integrin, alpha X (complement component 3 receptor 4 subunit)
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
lymphocyte cytosolic protein 1 (L-plastin)
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain),
member 6
LILRB3
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM
domains), member 3
LY86
lymphocyte antigen 86
LY96
lymphocyte antigen 96
MARCO
macrophage receptor with collagenous structure
MNDA
myeloid cell nuclear differentiation antigen
MRC1L1
mannose receptor, C type 1-like 1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
MYD88
myeloid differentiation primary response gene (88)
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
(p49/p100)
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase,
plasma)
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding
protein Rac1)
S100A4
S100 calcium binding protein A4
SAA4
serum amyloid A4, constitutive
SCARA5
scavenger receptor class A, member 5 (putative)
SPP1
secreted phosphoprotein 1
TFRC
transferrin receptor (p90, CD71)
THBS4
thrombospondin 4
Lipid Metabolism
AACS
acetoacetyl-CoA synthetase
AADACL1
neutral cholesterol ester hydrolase 1
ABHD5
abhydrolase domain containing 5
cell adhesion
cell adhesion
cell differentiation
Ig mediated immune response
Ig mediated immune response
Ig mediated immune response
Ig transport
cell adhesion
iron homeostasis
iron homeostasis
antigen presentation
hemoglobin degradation
hemoglobin degradation
antigen presentation
inflammatory cytokine
inflammatory response
inflammatory response
inflammatory response
cell adhesion
cell adhesion
cell adhesion
cell adhesion
immune response
T-cell activation
antigen presentation
inflammatory response
inflammatory response
innate immune response
innate immune response
inflammatory response
receptor-mediated endocytosis
inflammatory response
macrophage marker
macrophage marker
inflammatory response
transcription
inflammatory response
immune response
inflammatory response
acute phase response
iron transport
chemotaxis
iron homeostasis
cell adhesion
lipogenesis
cholesterol metabolism
lipolysis
ACACB
ACAD9
ACADM
ACAT1
ACOX1
ACSL1
ACSS2
AGPAT1
AGPAT9
ALOX12
ALOX5
AQP1
AQP7
AZGP1
CIDEA
CIDEC
DCI
DGAT1
DGAT2
ECHDC1
ECHDC3
ELOVL5
FABP4
FADS1
FADS2
FASN
GPD1L
GPR109A
HADH
HSDL2
KLB
LASS2
LDLR
LIPA
LIPE
LPCAT1
LPIN1
MECR
OSBPL9
PCCA
PECI
PECR
PGDS
PHYH
PKIG
PNPLA2
PNPLA3
RDH10
SCD
THRSP
acetyl-Coenzyme A carboxylase beta
acyl-Coenzyme A dehydrogenase family, member 9
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
acetyl-Coenzyme A acetyltransferase 1
acyl-Coenzyme A oxidase 1, palmitoyl
acyl-CoA synthetase long-chain family member 1
acyl-CoA synthetase short-chain family member 2
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid
acyltransferase, alpha)
1-acylglycerol-3-phosphate O-acyltransferase 9
arachidonate 12-lipoxygenase
arachidonate 5-lipoxygenase
aquaporin 1 (Colton blood group)
aquaporin 7
alpha-2-glycoprotein 1, zinc-binding
cell death-inducing DFFA-like effector a
cell death-inducing DFFA-like effector c
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A
isomerase)
diacylglycerol O-acyltransferase homolog 1 (mouse)
diacylglycerol O-acyltransferase homolog 2 (mouse)
enoyl Coenzyme A hydratase domain containing 1
enoyl Coenzyme A hydratase domain containing 3
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2,
SUR4/Elo3-like, yeast)
fatty acid binding protein 4, adipocyte
fatty acid desaturase 1
fatty acid desaturase 2
fatty acid synthase
glycerol-3-phosphate dehydrogenase 1-like
G protein-coupled receptor 109A
Hydroxyacyl-Coenzyme A dehydrogenase
hydroxysteroid dehydrogenase like 2
klotho beta
LAG1 homolog, ceramide synthase 2
low density lipoprotein receptor
lipase A, lysosomal acid, cholesterol esterase
lipase, hormone-sensitive
lysophosphatidylcholine acyltransferase 1
lipin 1
mitochondrial trans-2-enoyl-CoA reductase
oxysterol binding protein-like 9
propionyl Coenzyme A carboxylase, alpha polypeptide
peroxisomal D3,D2-enoyl-CoA isomerase
peroxisomal trans-2-enoyl-CoA reductase
prostaglandin-H2 D-isomerase
phytanoyl-CoA 2-hydroxylase
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
patatin-like phospholipase domain containing 2 (ATGL)
patatin-like phospholipase domain containing 3 (adiponutrin)
retinol dehydrogenase 10 (all-trans)
stearoyl-CoA desaturase (delta-9-desaturase)
thyroid hormone responsive (SPOT14 homolog, rat)
lipogenesis
lipogenesis
fatty acid oxydation
lipogenesis
fatty acid oxydation
lipogenesis
lipogenesis
lipogenesis
lipogenesis
leukotriene synthesis
leukotriene synthesis
glycerol transporter
glycerol transporter
lipolysis
fatty acid oxydation
lipogenesis
fatty acid oxydation
lipogenesis
lipogenesis
fatty acid oxydation
fatty acid oxydation
lipogenesis
fatty acid transport
lipogenesis
lipogenesis
lipogenesis
phospholipid metabolism
lipolysis
fatty acid oxidation
lipolysis
cholesterol metabolism
sphingolipid metabolism
cholesterol metabolism
cholesterol metabolism
lipolysis
phospholipid synthesis
lipogenesis
fatty acid oxydation
cholesterol transport
fatty acid oxidation
fatty acid oxidation
fatty acid biosynthesis
prostaglandin metabolism
fatty acid oxidation
lipolysis
lipolysis
lipolysis
retinol metabolism
lipogenesis
lipogenesis
WISP2
WNT1 inducible signaling pathway protein 2
Protein Metabolism
CST3
cystatin C
CSTB
cystatin B (stefin B)
CTSB
cathepsin B
CTSC
cathepsin C
CTSZ
cathepsin S
CTSZ
cathepsin Z
EMILIN2
elastin microfibril interfacer 2
LOX
lysyl oxidase
LOXL1
lysyl oxidase-like 1
LOXL2
lysyl oxidase-like 2
MMP19
matrix metallopeptidase 19
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV
collagenase)
PLAU
plasminogen activator, urokinase
PLAUR
plasminogen activator, urokinase receptor
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
RNF5
ring finger protein 5
RPN1
ribophorin I
TPST2
tyrosylprotein sulfotransferase 2
Response to Stress
ATOX1
ATX1 antioxidant protein 1 homolog (yeast)
MT1E
metallothionein 1E
MT1G
metallothionein 1G
PRDX6
peroxiredoxin 6
OXSR1
oxidative-stress responsive 1
Signal Transduction
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
AP2M1
adaptor-related protein complex 2, mu 1 subunit
EHD4
EH-domain containing 4
LGR4
leucine-rich repeat-containing G protein-coupled receptor 4
MAOA
monoamine oxidase A
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
Gene Expression
AES
amino-terminal enhancer of split
ATF3
activating transcription factor 3
CARHSP1
calcium regulated heat stable protein 1, 24kDa
E2F4
E2F transcription factor 4, p107/p130-binding
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF4A1
eukaryotic translation initiation factor 4A1
EN2
engrailed homeobox 2
IRF5
interferon regulatory factor 5
MCM3
minichromosome maintenance complex component 3
MSH6
mutS homolog 6 (E. coli)
NEUROG3
neurogenin 3
NPAS3
neuronal PAS domain protein 3
NRIP1
nuclear receptor interacting protein 1
PELP1
proline, glutamate and leucine rich protein 1
PWP1
PWP1 homolog (S. cerevisiae)
RNH1
ribonuclease/angiogenin inhibitor 1
SREBF1
sterol regulatory element binding transcription factor 1
SIRT1
sirtuin (silent mating type information regulation 2 homolog) 1 (S.
adipogenesis
tissue remodelling
tissue remodelling
tissue remodelling
proteolysis
proteolysis
tissue remodelling
tissue remodelling
tissue remodelling
tissue remodelling
tissue remodelling
tissue remodelling
tissue remodelling
proteolysis
proteolysis
proteolysis
proteolysis
protein glycosylation
peptidyl-tyrosine sulfation
copper ion transport
response to oxidative stress
response to oxidative stress
response to oxidative stress
response to oxidative stress
endocytosis signaling
intracellular trafficking
endocytosis signaling
membrane receptor
dopamin catabolism
membrane trafficking
transcription
transcription
translation
transcription
translation
translation
transcription
transcription
transcription
transcription
transcription
transcription
transcription
transcription
transcription
transcription
transcription
histone deacetylase
SRP9
TCEAL8
TDRD7
TNRC6B
TSEN54
TWIST1
VGLL3
Transport
ARF3
EXOC1
LAPTM5
NUP62
CD52
POP4
SLC19A2
SLC19A3
SLC35C2
SLC4A4
TXNDC5
Miscellaneous
BTBD7
CIDECP
CYYR1
DNAJC13
NOMO1
SH3BGRL
TMEM135
cerevisiae)
signal recognition particle 9kDa
transcription elongation factor A (SII)-like 8
tudor domain containing 7
triosephosphate isomerase 1
tRNA splicing endonuclease 54 homolog (S. cerevisiae)
twist homolog 1 (Drosophila)
vestigial like 3 (Drosophila)
translation
transcription
translation
translation
translation
transcription
transcription
ADP-ribosylation factor 3
exocyst complex component 1
lysosomal protein transmembrane 5
nucleoporin 62kDa
CD52 molecule
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
solute carrier family 19 (thiamine transporter), member 2
solute carrier family 19, member 3
solute carrier family 35, member C2
solute carrier family 4, sodium bicarbonate cotransporter, member 4
thioredoxin domain containing 5 (endoplasmic reticulum)
protein trafficking
exocytosis
lysosome transport
mRNA transport
carbohydrates transport
RNA transport
thiamine transport
thiamine transport
response to hypoxia
Na-HCO3 transport
vesicule-mediated transport
BTB (POZ) domain containing 7
cell death-inducing DFFA-like effector c pseudogene
cysteine/tyrosine-rich 1
DnaJ (Hsp40) homolog, subfamily C, member 13
NODAL modulator 1
SH3 domain binding glutamic acid-rich protein like
transmembrane protein 135
unknown
unknown
unknown
unknown
unknown
unknown
unknown