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Transcript
Complementary Medicines in the Management of Cholesterol
for Pharmacists
Assessment Test
HOW TO COMPLETE THE ASSESSMENT
You will find the answers to all the questions mostly in this manual. Please attempt all
questions and indicate your answer on the SEPARATE ASSESSMENT ANSWER SHEET
ONLY. When you have completed all questions, detach the sheet and return it to the
address provided.
1. Which of the following group of statements are true
I.
Cholesterol is not essential for life
II.
There is no healthy level for cholesterol in the body
III.
The prevalence of hypercholesterolaemia in Malaysia in 2006 was 53.5%
IV.
The only way to manage hypercholesterolaemia is to take medication
(A) III
(B) I,II,IV
(C) I,II,III
(D) II,III,IV
2. Which complementary medicines have been shown to have positive results compared to
statin medication in lowering cholesterol (also as adjunctive therapy)?
I.
Policosanol
II.
Fish oil
III.
Gugulipid
IV.
Garlic
V.
Vitamin B3
(A) I, II, III
(B) III, IV, V
(C) I, II, V
(D) II, III, IV
3. Which of the following complementary medicines are not recommended or
contraindicated in pregnancy and/or lactation?
I.
Policosanol
II.
Lecithin
III.
Garlic
IV.
CoQ10
(A) I, II
(B) I, II, IV
(C) I, III
(D) I, III, IV
4. Which of the following statements are TRUE for CoQ10?
I.
A fat-soluble vitamin-like antioxidant
II.
CoQ10 levels increases with ageing and exercise
III.
Reduce the degree of muscle pain (myalgia) associated with statin treatment
IV.
CoQ10 absorbs best when taken on an empty stomach or before meals
V.
It is recommended dosage is 100-150mg per day
(A) I, II, III
(B) II, III, V
(C) I, III, IV
(D) I, III, V
5. How does globe artichoke work on lowering hypercholesterolaemia?
(A) By acting as an antioxidant and therefore it prevents oxidation of LCL-C
(B) By increasing HDL-C levels and inhibiting platelet ‘clumping’
(C)
(D)
By inhibiting HMG-CoA reductase and thereby reducing cholesterol synthesis
By promoting bile production and increase bile flow, thus increasing the
emulsification of cholesterol into bile salts
6. The following statements are true for lecithin EXCEPT
(A) Naturally found in the myelin sheath which forms a protective covering for the
nerves
(B) Lecithin can be used as an adjunctive therapy with cholesterol-lowering drugs
without any adverse effects
(C) Higher doses of lecithin (more than the recommended dose) is needed to lower
cholesterol effectively
(D) It is contraindicated in patients who are on warfarin, aspirin and anti-platelet drugs
7. Which of the following has a drug-herb-vitamin interaction based on its clinical studies?
(Also refer to the Complementary Medicine Interaction Guide in this manual)
I.
Lecithin
II.
Fish oil
III.
Garlic
IV.
Gugulipid
V.
Vitamin C
(A) I, IV, V
(B) II, III, IV
(C) I, II, III
(D) III, IV, V
8. Which of the following statements are TRUE in the treatment of hypercholesterolaemia?
I.
Dietary and lifestyle changes should be considered and adopted before
considering drug therapy in patients without CHD or at high risk of CHD
II.
Some form of weight reduction by exercising (if necessary) is ideal to achieve
optimal weight and help to lower the risk of CHD
III.
Complementary medicines may be used as an adjunctive therapy with drugs in
the treatment of hypercholesterolaemia
IV.
Smoking and alcohol consumption has a compounding effect on CHD risk
(A) II,III,IV
(B) I, II, III, IV
(C) I, II, III
(D) I, II, IV
9. The following are important points that you need to highlight to your patients when taking
fish oil EXCEPT
(A) To be taken with meals as it absorbs better with a meal that consists of small
amounts of fat
(B) Fish oil decreases TG & TC levels only in hypercholesterolaemic patients based on
clinical trials
(C) Can be used safely with other complementary medicines or as an adjunctive
therapy with cholesterol-lowering medication
(D) Doses above 10gm a day should be suspended 1 week before surgery as it may
increase the risk of bleeding associated with surgery
10. Which of the following statement is FALSE?
(A) Policosanol has been found to decrease the activity of HMG-CoA reductase and
has undergone more than 30 clinical trials over a 15 year period
(B) Gugulipid’s active components, guggulsterones and gugulipid has been found to
have the ability to reduce cholesterol levels
(C) High intake of phytosterols and phytostanols has no effect on the absorption of fatsoluble vitamins & antioxidants
(D) Grape seed has been found to prevent damage to cholesterol and lining of the
artery by acting as an antioxidant.
Complementary Medicines in the Management of Cholesterol
for Pharmacists
Assessment Answer Sheet
Name: _____________________________________ MPS Membership No: ___________
Pharmacy / Institution: _______________________________________________________
Full Address: ______________________________________________________________
_________________________________________________________________________
Tel: __________________________
Fax: ________________________
Email: ________________________
Date: _______________________
Please circle the answer
Question
Answer
1
A
B
C
D
2
A
B
C
D
3
A
B
C
D
4
A
B
C
D
5
A
B
C
D
6
A
B
C
D
7
A
B
C
D
8
A
B
C
D
9
A
B
C
D
10
A
B
C
D
You may send in your answer by returning this sheet to the address/fax below, or via email
by stating the question number and answer.
Complementary Medicines in the Management of Cholesterol for Pharmacists
Malaysian Pharmaceutical Society
5B, Lorong Rahim Kajai 13
Taman Tun Dr Ismail
60000 Kuala Lumpur
Fax: 03-77263749
Email: [email protected]