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Tessa Bergsbaken, Ph.D.
Instructor, Department of Pathology and Laboratory Medicine
Center for Immunity and Inflammation
Rutgers New Jersey Medical School
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Work address:
Rutgers New Jersey Medical School
Department of Pathology and Laboratory Medicine
Center for Immunity and Inflammation
205 South Orange Ave.
Cancer Center, G-1210
Newark, NJ 07103
T: 973-972-7933
E: [email protected]
Home address:
Jersey City, NJ
Academic Postitions

2017-
Rutgers New Jersey Medical School, Newark, NJ
Instructor, Department of Pathology and Laboratory Medicine
Center for Immunity and Inflammation
Education & Training

2009-2016
Postdoctoral Fellow, Immunology
University of Washington, Seattle, WA
Advisor: Michael Bevan
Research topic: Differentiation and maintenance of tissue-resident memory
CD8+ T cells
2002-2008
Ph.D., Microbiology
Tessa Bergsbaken, Ph.D.
University of Washington, Seattle, WA
Advisor: Brad Cookson
Dissertation title: Caspase-1 activation and pyroptosis during the innate
immune
1998-2002
response to bacterial infection
B.S., Medical Microbiology and Immunology
University of Wisconsin, Madison,WI
Publications

Peer reviewed journal articles:
-T Bergsbaken, MJ Bevan, PJ Fink. Local inflammatory cues regulate differentiation and
persistence of tissue-resident memory CD8+ T cells. Cell Rep. 2017 Apr 4; 19(1):114-124.
-KA Deets, AM Berkley, T Bergsbaken, PJ Fink. Cutting Edge: Enhanced clonal burst size
corrects an otherwise defective memory response by CD8+ recent thymic emigrants. J
Immunol. 2016 Mar 15; 196(6):2450-2455.
-T Bergsbaken and MJ Bevan. Cutting Edge: Caspase-11 limits the response of CD8+ T cells
to low abundance and low affinity antigens. J Immunol. 2015 July 1; 195(1):41-45.
-T Bergsbaken and MJ Bevan. Proinflammatory microenvironments within the intestine
regulate the differentiation of tissue-resident CD8+ T cells responding to infection. Nat
Immunol. 2015 Apr;16(4):406-414.
-AS Woodward-Davis, T Bergsbaken, MA Delaney, and MJ Bevan. Dermal-resident versus
recruited γδ T cell response to cutaneous vaccinia virus infection. J Immunol. 2015 Mar 1;
194(5):2260-2267.
-T Bergsbaken, SL Fink, AB den Hartigh, WP Loomis, and BT Cookson. Coordinated host
responses during pyroptosis: caspase-1-dependent lysosome exocytosis and inflammatory
cytokine maturation. J Immunol. 2011 Sep 1; 187(5):2748-54.
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Tessa Bergsbaken, Ph.D.
-BL Deatherage, JC Lara, T Bergsbaken, SL Barrett, S Lara, BT Cookson. Biogenesis of
bacterial membrane vesicles. Mol Microbiol. 2009 Jun; 72(6):1395-1407.
-SL Fink, T Bergsbaken, and BT Cookson. Anthrax lethal toxin and Salmonella elicit the
common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms.
Proc Natl Acad Sci. 2008 Mar 18; 105(11):4312-7.
-T Bergsbaken and BT Cookson. Macrophage activation redirects Yersinia-infected host cell
death from apoptosis to caspase-1-dependent pyroptosis. PLoS Pathog. 2007 Nov;
3(11):e161.
-LA Cummings, WD Wilkerson, T Bergsbaken, BT Cookson. In vivo, fliC expression by
Salmonella enterica serovar Typhimurium is heterogeneous, regulated by ClpX, and
anatomically restricted. Mol Microbiol. 2006 Aug; 61(3):795-809.
-WW Lathem, T Bergsbaken, and RA Welch. Potentiation of C1 esterase inhibitor by StcE, a
metalloprotease secreted by Escherichia coli O157:H7. J Exp Med. 2004 Apr 19;
199(8):1077-87.
-WW Lathem, T Bergsbaken, SE Witowski, NT Perna, and RA Welch. Acquisition of StcE, a
C1 esterase inhibitor-specific metalloprotease, during the evolution of Escherichia coli
O157:H7. J Infect Dis. 2003 Jun 15; 187(12):1907-14.
Review articles:
-T Bergsbaken and BT Cookson. Innate immune response during Yersinia infection: critical
modulation of cell death mechanisms through phagocyte activation. J Leukoc Biol. 2009
Nov; 86: 1153-1158.
-T Bergsbaken and BT Cookson. Pyroptosis: host cell death and inflammation. Nat Rev
Microbiol. 2009 Feb; 7(2):99-109.
Presentations

3
Tessa Bergsbaken, Ph.D.
-T Bergsbaken, MJ Bevan, and PJ Fink. Intestinal inflammation drives differentiation of
tissue-resident memory CD8+ T cell populations. The American Association of
Immunologists Annual Meeting, 2016. (selected oral presentation)
-T Bergsbaken and MJ Bevan. Proinflammatory microenvironments within the intestine
regulate the differentiation of tissue-resident CD8+ T cells responding to infection.
Midwinter Conference of Immunologists, 2015. (selected oral presentation)
-T Bergsbaken and MJ Bevan.Caspase-11 Regulates the Expansion of CD8+ T Cells.
Cancer Research Institute - Cancer Immunotherapy Symposium, 2013.
-T Bergsbaken and MJ Bevan. Visualizing the intestinal CD8+ T cell response. Cancer
Research Institute - Cancer Immunotherapy Symposium, 2012.
-T Bergsbaken and MJ Bevan. Caspase-1 activation in CD8+ T cells. Regional Centers of
Excellence National Meeting, 2012.
-T Bergsbaken and MJ Bevan. Caspase-1 activation in CD8+ T cells. Cancer Research
Institute - Cancer Immunotherapy Symposium, 2011.
-T Bergsbaken and BT Cookson. Coordinated host responses during pyroptosis: lysosome
exocytosis and inflammatory cytokine maturation. General Meeting - American Society for
Microbiology, 2008.
-T Bergsbaken and BT Cookson. Macrophage activation redirects Yersinia-infected host cell
death from apoptosis to caspase-dependent pyroptosis. FASEB Conference on Microbial
Pathogenesis, 2007. (selected oral presentation)
-T Bergsbaken and BT Cookson. TLR stimulation redirects Yersinia-infected host cell death
from apoptosis to pyroptosis. Gordon Conference on Microbial Toxins and Pathogenicity,
2006.
4
Tessa Bergsbaken, Ph.D.
-T Bergsbaken and BT Cookson. Yersinia pseudotuberculosis-induced macrophage death
occurs by two distinct pathways. General Meeting - American Society for Microbiology,
2004.
Teaching & Service

Teaching:
-Guest Lecturer - University of Washington, 2006/2008. Medical Bacteriology, MICROM 443.
-Teaching Assistant - University of Washington, General Microbiology/General Microbiology
Laboratory, MICROM 301/302.
-Teaching Assistant – University of Washington, 2003. Introductory Biology: Molecular,
Cellular and Developmental Biology Lecture/Laboratory, BIOL 200.
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Tessa Bergsbaken, Ph.D.
Service:
-Graduate Student Retreat Organizer - University of Washington, 2006-2007.
-Microbiology Departmental Retreat Organizer - University of Washington, 2008.
Fellowships & Awards

-Trainee Abstract Award - The American Association of Immunologists, 2016.
-Irvington Institute Fellowship - Cancer Research Institute, 2011-2014.
-Developmental Immunology Post-Doctoral Traineeship - University of Washington, 2010.
-Helen Raiboff Whiteley Fellowship - University of Washington, 2008.
-Cellular and Molecular Biology Training Grant - University of Washington, 2003-2007
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