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Additional file 1 1.1. Journals publishing at least 15 randomized controlled trial (RCT) reports (search date February 2, 2014) indexed in PubMed with the keywords randomized controlled trial with the following filters: study type RCT, English language, human studies, published between January 1, 2013 and March 31, 2013, and with an abstract available Journal's Name Accident Analysis and Prevention Acta Anaesthesiologica Scandinavica Addictive Behaviors Addiction AIDS and Behavior Alcoholism- Clinical and Experimental Research American Heart Journal American Journal of Cardiology American Journal of Clinical Nutrition American Journal of Kidney Diseases American Journal of Ophtalmology Anesthesia and Analgesia Annals of Oncology Antimicrobial Agents and Chemotherapy Appetite Archives of Gynecology and Obstetrics Archives of Physical Medicine and Rehabilitation Atherosclerosis Behaviour Research and Therapy BJOG- an International Journal Of Obstetrics and gynaecology BJU International Blood BMC Musculoskeletal Disorders BMC Psychiatry BMC Public Health British Journal of Anaesthesia British Journal of Cancer British Journal of Clinical Pharmacology British Journal of Nutrition Cancer Circulation- Heart Failure Circulation Clinical Infectious Diseases Clinical Interventions in Aging Clinical Journal of the American Society of Nephrology Clinical Journal of Pain Impact Factor 1,964 2,355 2,021 4,746 2,979 3,421 4,497 3,209 6,504 5,294 3,631 3,300 7,384 4,565 2,541 1,330 2,358 3,991 3,471 3,760 3,046 9,060 1,875 2,233 2,076 4,237 5,082 3,578 3,302 4,901 6,684 15,202 9,374 2,651 5,068 2,552 Clinical Oral Investigations Clinical Rehabilitation Clinical Therapeutics Contemporary Clinical Trials Diabetes Care Diabetes Obesity & Metabolism Drug and Alcohol Dependence European Heart Journal European Journal of Applied Physiology European Journal of Cancer European Journal of Clinical Nutrition European Journal of Clinical Pharmacology European Journal of Heart Failure Experimental Brain Research Journal of Affective Disorders Journal of Alternative and Complementary Medicine Journal of the American College of Cardiology Journal of Applied Physiology Journal of Clinical Endocrinology and Metabolism Journal of Clinical Oncology Journal of Clinical Periodontology Journal of Clinical Pharmacology Journal of Dentistry Journal of Drugs in Dermatology Journal of Infectious Diseases Journal of Medical Internet Research Journal of Nutrition Journal of Pediatric Journal of Sports Science Journal of Strength and Conditioning Research Journal of Substance Abuse Treatment Journal of Urology JAMA Lancet Lancet Oncology Metabolism New England Journal of Medicine Neurorehabilitation and Neural Repair Nicotine & Tobacco Research Nutrition Obesity (Silver Spring) Osteoporosis International Pain Pediatrics PLoS One 2,200 2,191 2,230 1,597 7,735 5,181 3,141 14,097 2,660 5,061 2,756 2,741 5,247 2,221 3,295 1,464 14,086 2,660 6,430 18,038 3,688 2,963 3,200 1,161 5,848 3,768 4,196 4,035 2,082 1,795 1,985 3,696 29,978 39,060 25,117 4,514 51,658 4,278 2,477 2,859 3,491 4,039 5,644 5,119 3,730 Psychology & Health Psychopharmacology (Berl) Respiratory Medicine Schizophrenia Research Stroke Surgical Endoscopy and Other Interventional Techniques Trials Vaccine Zh Nevrol Psikhiatr Im S S Korsakova Zhongguo Zhen Jiu 1,950 4,595 2,585 4,590 6,158 3,427 2,206 3,492 NA NA 1.2. The 10 journals with the highest impact factor (Journal Citation Report 2012) for 14 medical areas. Only journals publishing at least one RCT report in the 3 last issues were included. Journal's name Anaesthesia Anesthesia and Analgesia Anesthesiology British Journal of Anaesthesia European Journal of Anaesthesiology European Journal of Pain Minerva Anestesiologica Pain Pain Practice Regional Anesthesia and Pain Medicine Circulation Impact Factor 3,486 3,300 5,163 4,237 2,792 3,067 2,818 5,644 2,605 3,464 15,202 Circulation- Cardiovascular Genetics 6,728 Circulation- Cardiovascular Interventions 6,543 Circulation- Heart Failure 6,684 Circulation Research 11,861 European Heart Journal 14,097 JACC- Cardiovascular Imaging 6,164 JACC- Cardiovascular Interventions 6,543 Journal of the American College of Cardiology 14,086 Nature Reviews in Cardiology 10,400 Acta Neuropathologica Alzheimers & Dementia Annals of Neurology Archives of Neurology Brain Lancet Neurology Nature Reviews Neurology Neurology Neuro-oncology Sleep Medicine Reviews American Journal of Respiratory and Critical 9,734 14,483 11,193 7,685 9,915 23,917 15,518 8,249 6,180 8,681 11,041 Specialties Anesthesiology Anesthesiology Anesthesiology Anesthesiology Anesthesiology Anesthesiology Anesthesiology Anesthesiology Anesthesiology Anesthesiology Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Cardiac & Cardiovascular systems Clinical neurology Clinical neurology Clinical neurology Clinical neurology Clinical neurology Clinical neurology Clinical neurology Clinical neurology Clinical neurology Clinical neurology Critical Care Medecine Selected if at least 3 RCTs of clinical trials in 3 last issues Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No No Yes Yes No Yes Yes No Yes Yes Yes Yes Care Medicine Chest Critical Care Critical Care Medicine Current Opinion in Critical Care Intensive Care Medicine Journal of Neurotrauma Minerva Anestesiologica Neurocritical Care Resucitation Academic Emergency Medicine American journal of Emergency Medecine Annals of Emergency Medicine Emergencias Emergency Medicine Journal Injury Journal of Trauma - Injury infection and Critical Care Prehopospital Emergency Care Resuscitation Scandinavian Journal of Trauma Resuscitation & Medicine Arteriosclerosis Thrombosis and Vascular Biology Blood Blood Reviews Circulation Research Haematologica - The Hematology Journal Journal of Cerebral Blood Flow and Metabolism Journal of Thrombosis and Haemostasis Leukemia Stem Cells Thrombosis and Haemostasis AIDS Clinical Infectious Diseases Current Opinion in HIV and AIDS Current Opinion in Infectious Diseases Emerging Infectious Diseases Eurosurveillance JAIDS- Journal of Acquired immune Deficinecy Syndromes Journal of Antimicrobial Chemotherapy Journal of Infectious Diseases Lancet Infectious Diseases Annals of Internal Medicine 5,854 4,718 6,124 2,967 5,258 4,295 2,818 3,038 4,104 1,757 1,704 4,285 2,578 1,645 2,174 Critical Care Medecine Critical Care Medecine Critical Care Medecine Critical Care Medecine Critical Care Medecine Critical Care Medecine Critical Care Medecine Critical Care Medecine Critical Care Medecine Emergency Medicine Emergency Medicine Emergency Medicine Emergency Medicine Emergency Medicine Emergency Medicine Yes Yes Yes No Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 2,348 Emergency Medicine No 1,859 4,104 Emergency Medicine Emergency Medicine Yes Yes 1,680 Emergency Medicine Yes 6,338 Hematology Yes 9,060 6,000 11,861 5,935 Hematology Hematology Hematology Hematology Yes Yes Yes No 5,398 Hematology No 6,081 10,164 7,701 6,094 6,407 9,374 4,704 4,870 5,993 5,491 Hematology Hematology Hematology Hematology Infectious Diseases Infectious Diseases Infectious Diseases Infectious Diseases Infectious Diseases Infectious Diseases No Yes No Yes Yes Yes No No Yes Yes 4,653 Infectious Diseases Yes 5,338 Infectious Diseases 5,848 Infectious Diseases 19,966 Infectious Diseases 13,976 Medicine, General & Internal Yes Yes Yes Yes Archives of Internal Medicine BMC Medicine British Medical Journal Canadian Medical Association Journal JAMA Journal of Internal Medicine Lancet New England Journal of Medicine Plos Medicine Annals of Neurology Annual Review of Neuroscience Behavioral and Brain Sciences Brain Molecular Psychiatry Nature Neurosciences Neurosci Nature Reviews Neuroscience Neuron Trends in Cognitive sciences Trends Neurosci Biochimica et Biopsysica - Reviews of Cancer CA- A Cancer Journal for Clinicians Cancer Cell Cancer Discovery JNCI- Journal of the National Cancer Institute Journal of Clinical Oncology Lancet Oncology Leukemia Nature Reviews Cancer Nature Reviews Clinical Oncology Archives of Disease in Childhood Archives of Disease in Childhood- Fetal and Neonatal Edition Archives Pediatrics Adolescent Medicine European Child & Adolescent Psychiatry Journal of Pediatric Journal of the American Academy of Child and Adolescent Psychiatry Pediatric Allergy and Immunology Pediatrics Seminars in Fetal & Neonatal Medicine The Pediatric Infectious Disease Journal American journal of Psychaitry Archives of General Psychaitry Biological psychiatry 10,579 6,679 17,215 6,465 29,978 6,455 39,060 51,658 15,253 11,193 20,614 18,571 9,915 14,897 15,251 31,673 15,766 16,008 13,582 Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Medicine, General & Internal Neurosciences Neurosciences Neurosciences Neurosciences Neurosciences Neurosciences Neurosciences Neurosciences Neurosciences Neurosciences Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No Yes Yes Yes No No Yes No Yes 9,033 Oncology No 153,459 24,755 10,143 Oncology Oncology Oncology Yes No Yes 14,336 Oncology Yes 18,038 25,117 10,174 35,000 14,771 3,051 Oncology Oncology Oncology Oncology Oncology Pediatrics Yes Yes Yes No No Yes 3,451 Pediatrics Yes 4,282 3,699 4,035 Pediatrics Pediatrics Pediatrics Yes Yes Yes 6,970 Pediatrics Yes 3,376 5,119 3,505 3,569 14,721 13,772 9,247 Pediatrics Pediatrics Pediatrics Pediatrics Psychiatry Psychiatry Psychiatry Yes Yes No Yes Yes No No British Journal of Psychiatry Journal of Psychiatry & Neuroscience Molecular Psychiatry Neuropsychopharmacology Psychoterapy and Psychosomatics Schizophrenia Bulletin World Psychiatry Annals of Rheumatic Diseases Arthritis and Rheumatology Arthritis Care & Research Arthritis Research & Therapy Best Practice & Research in Clinical Rheumatology Curr Opin Rheumatol Nature Reviews Rheumatology Osteoarthritis and Cartilage Rheumatology Seminars in Arthritis and Rheumatism American Journal of surgical pathology American Journal of Transplantation Annals of Surgery Annals Surgical Oncology Archives of Surgery British Journal of Surgery Endoscopy Journal of neurology Neurosurgery and Psychiatry Journal of the American College of Surgeons Surgery for obesity and Related Diseases 6,606 6,242 14,897 8,678 7,230 8,486 8,974 9,111 7,477 3,731 4,302 Psychiatry Psychiatry Psychiatry Psychiatry Psychiatry Psychiatry Psychiatry Rheumatology Rheumatology Rheumatology Rheumatology No No Yes No No No No Yes Yes Yes Yes 3,550 Rheumatology Yes 5,191 9,745 4,262 4,212 3,806 4,868 6,192 6,329 4,120 4,839 5,735 Rheumatology Rheumatology Rheumatology Rheumatology Rheumatology Surgery Surgery Surgery Surgery Surgery Surgery Surgery No No Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 4,924 Surgery Yes 4,500 Surgery Yes 4,121 Surgery Yes 1.3. Duplicate journals Annals of Neurology Brain Leukemia Circulation Research Minerva Anestesiol Anesthesia and Analgesia Atherosclerosis Blood British Journal of Anaesthesia Circulation- Heart Failure Circulation Clinical Infectious Diseases European Heart Journal Journal of the American College of Cardiology Journal of Clinical Oncology Journal of Infectious Diseases Journal of Pediatric JAMA Lancet Lancet Oncology New England Journal of Medicine Pain Pediatrics Molecular Psychiatry