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Version of 22nd July 2011 French School of Public Health Ecole des Hautes Etudes en Santé Publique MASTER OF PUBLIC HEALTH 2011/2012 SCHEDULE YEAR 2 EPIDEMIOLOGY Master of Public Health - Semester 3 Weeks 36 to 40: from Tuesday 06th September to Tuesday 04th October 2011 Module 203 Core curriculum « Epidemiology » Course Director : Pr. Moïse Desvarieux Location: Reid Hall 4 rue de Chevreuse – 75006 PARIS Tuesday September 06th Tuesday September 13th Tuesday September 20th Tuesday September 27th Tuesday October 04th 9h 9h 9h 9h 8h30 Introduction & Fundamental concepts Study Design 1: case-control studies. Clinical trials (1) Confounding and bias Screening Ryan Demmer (Columbia University Mailman School of Public Health) Anders Boyd (Inserm) Moïse Desvarieux (Inserm, Columbia Katherine Keyes University Mailman School (Columbia of Public Health and EHESP) University Mailman School of Public Health) Bill Friedewald (Columbia University Mailman School of Public Health) 12h : Lunch 12h : Lunch 12h : Lunch 12h : Lunch 12h : Lunch 14h 14h 14h 14h 14h Causal Inference Study Design 2: - cohort studies - ecological studies Clinical trials (2) Ethical issues controversies in Health Moïse Desvarieux Katherine Keyes Bill Friedewald 17h (Assignment: EPV causal inference 17h 17h (Assignment: EPV CCS, (EPV: Randomized trials) Cohorts, Ecological studies) and Sample size calculations for Public various study designs. Data collection, centralization, standardization and quality Ron Bayer (Columbia control. Design of study University Mailman School questionnaires and data of Public Health) collection instruments Anders Boyd 17h 17h (EPV: Bias and (EPV: Screening) Confounding) Master of Public Health - Semester 3 Week 42: Wednesday 19th to Friday the 21st of October 2011 Location: (to be confirmed) Exams for core modules: (to be confirmed) Module 202 Social and Behavioral Sciences Module 203 Epidemiology Module 204 Information Sciences and Biostatistics Module 205 Management and Health Policy Sciences Module 206 Environmental and Occupational Health Sciences Master of Public Health - Semester 3 Week 43: from Monday 24th to Friday 28th of October 2011 Module 210 Minor A: “Infectious Disease Epidemiology” Coordinator: Dr. Andrea HOWARD Monday October 24th 9h Overview of the Biologic Basis of Infectious Disease Epidemiology, Immune Response, and Methods for Detection of Infectious Diseases Application of Fundamental Epidemiological Study Designs to Infectious Disease Problems of Public Health Significance: Group Work and Student Presentations Andrea Howard, Columbia University 12h : Lunch 14h Overview: Biology of Mycobacterium tuberculosis infection Tuesday October 25th 9h Molecular Methods Used in Infectious Disease Epidemiology Location: Reid Hall 4 rue de Chevreuse – 75006 PARIS Wednesday October 26th 9h Introduction to Concepts of Transmission and Dynamics Application of Molecular Epidemiology: Investigating Transmission of MethicillinResistant Staphylococcal aureus (MRSA) Thursday October 27th 9h Pandemic Influenza A (H1N1): Public Health Investigation and Response Evaluating Interventions on the Population Level: Modelling Influenza Transmission and Control Friday October 28th 9h Natural History of Human Papillomavirus (HPV) Infection and Development of Cervical Cancer Critical Review of Primary Studies Evaluating HPV Vaccination Discussion: The HPV Vaccine Mandate Controversy Andrea Howard, Columbia University 12h : Lunch 14h Infectious Disease Surveillance Outbreak Detection and Investigation of Foodborne Illness Evaluation of Diagnostics Tests: Critical Review of Tuberculin Skin Tests and T-cell-based Assays for Latent TB Infection Discussion: Critical Review of Primary Studies of TB Control Strategies Targeting People with Latent TB Infection Andrea Howard, Columbia Andrea Howard, University University 17h 17h Pascal Crepey, EHESP 12h : Lunch 14h Overview: Biology of HIV Infection Criteria for Causality: Critical Review of Primary Studies of Male Circumcision to Prevent HIV Transmission Discussion: Critical Review of Modelling Papers Evaluating the Effects of Male Circumcision on HIV Transmission at the Population Level Columbia Andrea Howard, Columbia University 17h Andrea Howard, Columbia University 12h : Lunch 14h Biology and Natural History of Chlamydia trachomatis Infection Andrea Howard, Columbia University 12h : Lunch Epidemiology and Control of Malaria Critical Review of Primary Studies Evaluating Chlamydia Screening to Prevent Reproductive Sequelae Andrea Howard, Columbia University 17h Jacques Lebras, Malaria French Reference Centre (CNR Palu), University Paris 16h30: Module evaluation 17h Master of Public Health Week 44/45: from Wednesday 02nd to Friday 04th and Monday 07th to Tuesday 08th of November 2011 (Start Wednesday because of November the 1st and extends to Tuesday 8th) Module 211 Minor B: “Chronic Disease Epidemiology” Coordinator: Ryan Demmer Location: Reid Hall 4 rue de Chevreuse – 75006 PARIS Wednesday November 02rnd Thursday November 03rd Friday November 04th Monday November 07th Tuesday November 08th 9h 9h 9h 9h 9h Introduction to Chronic Disease -Ryan DEMMER, Columbia University Pharmacoepidemiology Meta-analysis & systematic Cancer Epidemiology reviews -Philippe RAVAUD -Alfred NEUGUT EHESP (tentative) Columbia University Diet and Chronic Disease -David R. JACOBS Jr University of Minnesota -Moise DESVARIEXU Columbia University EHESP -Joe KIM Roche, UK & Department of Medical Statistics, London School of Hygiene and Tropical Medicine 12h : Lunch 12h : Lunch 12h : Lunch 12h : Lunch 12h : Lunch 14h 14h 14h 14h 14h Genome Wide Association Studies -Brandon PIERCE University of Chicago Chronic Disease from a Gene Expression Studies Historical Perspective -Gerald OPPENHEIMER -Ryan DEMMER Columbia University Columbia University Cancer Epidemiology Continued Cardiovascular Disease Epidemiology -Alfred NEUGUT Columbia University Dr. Alan BERGER University of Minnesota Hygiene and Trop Diabetes Epidemiology -Ryan DEMMER, Columbia University 16h30: Module evaluation 17h 17h 17h 17h 17h Master of Public Health – M2 Week 48: Monday 28th to Friday 02nd of December 2011 Location: to be announced Exams minors: Monday 28th of November: tba Tuesday 29th of November: tba Wednesday 30th of November: tba Thursday 01st of December: tba Friday 02nd of December: Master of Public Health – Semester 3 Week 50: from Monday 12th to Friday 16th of December 2011 Module 223 Major A: “Design, Concept and Methods in Epidemiology” Coordinators: Sharon Schwartz Location: Reid Hall 4 rue de Chevreuse – 75006 PARIS Monday December 12th 9h Tuesday December 13th 9h Wednesday December 14th 9h Thursday December 15th 9h Friday December 16th 9h Introduction to casual inference Study designs: Randomized control trials. Natural experiments. Cohort study designs Case control studies I Identifying causes (main effects and confounding) Sampling and power 12h : Lunch 14h 12h : Lunch 14h 12h : Lunch 14h 12h : Lunch 14h 12h : Lunch 14h Implications of causality for Cohort studies basic epidemiologic concepts Case control studies II Explaining causes (mediation Measurement issues and effect modification) 16h30: Module evaluation 17h 17h 17h 17h 17h Master of Public Health - Semester 3 Week 51 and 52: from 19th to 30th of December 2011 Holidays (to be confirmed) Week 01: from Monday 02nd to Friday 06th of January 2012 Master of Public Health – Semester 3 Module 224 Major B: “Analysis in Epidemiology” Coordinator: Mary Beth Terry Location: Reid Hall 4 rue de Chevreuse – 75006 PARIS Monday 02nd January Tuesday 03rd January Wednesday 04th January Thursday 05th January Friday 06th January 9h 9h 9h 9h 9h Rationale for multi-variable model Confounding Logistic regression Matching: Conditional models and methods Mary Beth Terry Mary Beth Terry (Columbia Mary Beth Terry University Mailman School of Public Health) Mary Beth Terry Survival models: Kaplan Meir Cox Modeling Mary Beth Terry 12h : Lunch 12h : Lunch 12h : Lunch 12h : Lunch 12h : Lunch 14h 14h 14h 14h 14h Statistical considerations: Pure Count Interactive Extension of logistic models, Other cohort models: polytomous Poisson Advanced topics Mary Beth Terry Mary Beth Terry Mary Beth Terry Mary Beth Terry Mary Beth Terry 16h30: Module evaluation 17h 17h 17h 17h 17h Week 04: from Monday 23rd to Friday 27th of January 2012 Master of Public Health Semester 3 Optional module: « Mental health epidemiology » Coordinator : Viviane Kovess Masfety Location: Reid Hall 4 rue de Chevreuse – 75006 PARIS Monday January 23rd Tuesday January 24th January January 25th Thursday January 26th 9h V.Kovess Masfety -introduction -mental health definitions and paradigms -normal and pathological frontiers 9h J.Helzer V.Kovess 9h 12h 9h E.Bromet J.Helzer Mental health survey’s methodology Case-finding: surveys versus registers sampling (general and specific populations) Case ascertainment Survey instruments (checklists, diagnostic instruments) - -validation and concordance -translation for international surveys comparison 12h : Lunch 12h : Lunch 12h : Lunch 14h E.Bromet 14h E.Bromet 14h J.Helzer 10h30 J.Helzer -psychiatric disorders classifications -DSM V prospective mental health determinants -genetic/ environment, - social factors -traumas ,life events PTSD -Suicide and behavioural problems -WMH main results and international comparisons -clinical epidemiology : studying Psychosis 17h 17h Mental disorders over the course of life -Longitudinal surveys --Onset and incidence --Medical illness consequences --Mental disorders and mortality -Description of the various dependences including pathological gambling and bulimia : epidemiology and risk factors Friday January 27th 9h Mental health psychiatry and Health care utilisation law in France and Europe ( (V.Kovess) H.J.Salize) -Involuntary placements in -use of care for mental health France problems in France and the -EU comparisons on EU involuntary placements -medical non medical -Psychiatric patient’s providers, formal and responsibility determination informal providers roles -Psychiatric care in prisons -pharmaco epidemiology for psychotropics 12h : Lunch 12h : Lunch 14h S.Stansfeld 14h special group epidemiology A.Lovell V.Kovess Work, disability and Mental Health -children V.Kovess - homeless, prisoners A.Lovell 16h30: Module evaluation 17h 17h 17h Master of Public Health – M2 week 05: Monday 30th and Tuesday 31st of January 2012 Location: to be announced Examination of Major modules Monday 30th of January (tba) Tuesday 31st of January (tba) Master of Public Health – M2 Week 06 - 23: Monday 06th of February to Friday 08th of June 2012 Location: internship Internship Master of Public Health – M2 Week 26: Monday 25th to Friday 29th of June 2012 Location: EHESP Rennes Resit for minor and major modules (to be announced) Master of Public Health – M2 Week 27: Monday 02nd, Tuesday 03rd and Friday 06th of July 2012 Location: EHESP Rennes Defense of thesis and commencement ceremony Monday 02nd of July: Defense of thesis (tba) Tuesday 03rd of July: Defense of thesis (tba) Friday 06th of July: Commencement ceremony