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Download Product Datasheet BRMS1 Antibody Catalog Number: IPW1211
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Product Datasheet BRMS1 Antibody Catalog Number: IPW1211 Alternative name(s): Breast cancer metastasis-suppressor 1; BRMS1 Unit Size: 25μg/25μl, 50μg/50μl, 100μg/100μl Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Clonality: Rabbit polyclonal Storage/Stability: Store at -20℃/1 year Immunogen: Synthetic peptide conjugated to KLH, selected from the Internal region of Human BRMS1 . Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Specificity/Sensitivity: BRMS1 antibody detects endogenous levels of total BRMS1 protein. Reactivity: Human,Mouse,Rat Applications: WB: 1:500~1:1000 IHC:1:50-1:200 Gene ID : 25855 Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that Function: are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. For Research Use Only
