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Incidence Around47%ofcancercasesand55%ofcancerdeathsoccurinlessdevelopedregions.(1) Incidenceofcanceris15%formeninhigherdevelopedregionsand8%higherinwomen CancerkillsmorepeopleeachyeargloballythanAIDS,tuberculosisandmalariacombined,the numberofcancerdeathsareincreasingrapidly.(2) Femalebreast,stomach,prostate,liver,colorectalandcervicalcancersconstitutemorethan58%of theestimatedglobalcancerburden.(3) Femalebreastcanceristheonlycancerwhichiscommoninallregions,regardlessoftheirlevelsof development(3).Thissaid,lungcanceristhemostcommoncancerworldwide.Formeninmany countriesitistheleadingcauseofcancerdeathsandforwomenthemostcommonformofcancer deathinNorthAmerica,partsofEuropeandChina.(3) 30%ofcancerdeathsarelinkedto5behaviouralanddietaryrisks:highbodymassindex,lowfruit andvegetableintake,lackofphysicalactivity,tobaccouseandalcoholuse.(4) Tobaccousealoneisthemostcrucialriskfactorincausingcancerdeaths,itisresponsibleforover20% ofglobalcancerdeathsand70%ofgloballungcancerdeaths.(4) Otherleadingriskfactorsforcancerinlow-andmiddle-incomecountriesarechronicinfectionsfrom hepatitisB(HBV),hepatitisCvirus(HCV)andsometypesofHumanPapillomaVirus(HPV. Cervicalcancer,whichiscausedbyHPV,isaleadingcauseofcancerdeathamongwomeninlowincomecountries.Upto20%ofcancerdeathsareduetoinfectionbyHBVandHPV.(4) Over 1.6 million new cases of breast cancer were diagnosed worldwide last year, a major conference in Glasgow has been told (6) Care Only5%ofglobalspendingoncancerisinthedevelopingworld(1) Predictions In2008thenumberofnewcaseswas12.7million,ifcancerspecifictrendscontinueasexpected thenby2030therewillbeanincreaseinannualincidenceofcancerto22.2million(3) DifferentCancers • • • • • • Cancerisaleadingcauseofdeathworldwide,accountingfor8.2milliondeathsin2012.Themain typesofcancerare: Lung(1.59milliondeaths) Liver(745000deaths) Stomach(723000deaths) Colorectal(694000deaths) Breast(521000deaths) Oesophagealcancer(400000deaths)(1). Prevention 30%ofcancerscouldbeprevented. Currentlyalmost4.2millionpeopleperyeardieprematurely(aged30to69years)dueto thediseaseacrosstheworld “Despiteexcitingadvances,thisReportshowsthatwecannottreatourwayoutofthe cancerproblem,”statesDrChristopherWild,DirectorofIARCandco-editorofthebook. “Morecommitmenttopreventionandearlydetectionisdesperatelyneededinorderto complementimprovedtreatmentsandaddressthealarmingriseincancerburdenglobally.” (5) In2012,theworldwideburdenofcancerrosetoanestimated14millionnewcasesperyear, afigureexpectedtoriseto22millionannuallywithinthenexttwodecades.(5) Thespirallingcostsofthecancerburdenaredamagingtheeconomiesofeventherichest countriesandarewaybeyondthereachofdevelopingcountries,aswellasplacing impossiblestrainsonhealth-caresystems.In2010,thetotalannualeconomiccostofcancer wasestimatedtoreachapproximatelyUS$1.16trillion.Yetabouthalfofallcancerscouldbe avoidedifcurrentknowledgewasadequatelyimplemented.(5) References: 1. 2. 3. 4. 5. 6. CancerResearchFactsheets http://publications.cancerresearchuk.org/cancerstats Scalingupcancerdiagnosisandtreatmentindevelopingcountries:WhatcanwelearnfromtheHIV/AIDSepidemic?Annalsof Oncology,Vol.21No.4,pp.680-682 Bray,F.GlobalcancertransitionsaccordingtoHDI,TheLancetOncology,Vol.13,No.8.pp-790-801 WHOfactsheetNo297 http://www.who.int/mediacentre/factsheets/fs297/en/ WorldCancerReportPressRelease http://www.iarc.fr/en/media-centre/pr/2014/pdfs/pr224_E.pdf Prof.BoylespeakingattheEuropeanBreastCancerConferencehttp://www.irishhealth.com/article.html?id=23393