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Health and Safe
Travel - Coping
with
Travel Medicine
First Annual Summer School
Mount Juliet, June 2007
Dom Colbert MD FRCSI BSc CTH MFTM
Irish Society of Travel Medicine
1
Four recent mistakes
Š A doctor gives yellow fever to one of a
couple going to India. The other half
comes to me because he has seen on the
internet that there is no need for this
Š He is right. There is no yellow fever in
India. It is still confined to Sub Saharan
Africa and some parts of Central and
South America.
WHB give C and P to a group of school
girls going to Kolkata in April. Their
leader comes to me and asks the
pertinent question
Š She is right. Malaria risk in India follows this
pattern:
Š Kolkata May to November
Š Delhi July to September
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Š Chennai July to December
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Š Mumbai July to October
Š Goa..7 cases p falciparum
Dec 2006 -Jan 2007 !
A doctor gives C and P to someone backpacking in East
Africa. She gets malaria. Was flown to S Africa very
sick and has confirmed falciparum malaria.
Š This is a serious mistake and the
girl could have died. She was a
student in Trinity at the time. The
doctor ‘thought he read that C and
P was ok for Africa’. ‘
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Should I give typhoid to a
an 18 month old toddler
going to visit family in
India?>
Š No it is not used under 2 years of age.
Š Please note the difference between a
‘booster’ e.g. for hep A and starting
from scratch as in typhoid vaccine!
HOW RISKY IS FOREIGN
TRAVEL?
Š Rose examined records of 7 million US
tourists who went to less developed
countries(<90 days, median 19 days)
Š 60 - 70% chance of getting an illness 8%
sought medical care
Š < 1.0% hospitalized
Š On return 26% had a bout of diarrhea, a
respiratory illness, a skin problem or a
fever !
INDIVIDUAL RISK VARIES
Š WHERE you go
Š WHEN you go
Š WHAT you did
Š DURATION of trip
Š OWN HEALTH STATUS
Š PRECAUTIONS taken
Š UNEXPECTED….
OVERALL RISKS %
Š
Š
Š
Š
Š
Š
Š
Š
Š
DIARRHEA 34
RESPIRATORY INFECTION 26
SKIN DISORDER 8
FEVER 7
MOUNTAIN SICKNESS 6
MOTION SICKNESS 5
ACCIDENT INJURY 5
NON SPECIFIC FEVER 3
OTHER 13 (e.g. unmasks disease, AIDS HIV
Hepatitis , snake bites etc )
The Big Four
Š DIARRHEA
Š RESPIRATORY ILLNESS
Š SKIN PROBLEM
Š FEVER
Although infections account
for only 1% this is still a large
number
Š Republic 43 cases reported of malaria in
2005 ( 2 died). 100+ reported 2006
Š 2000 reported in the UK in 2005 (9 died)
Š In UK 75% have not taken antimalarial
prophylactics
Š In 20% the wrong antimalarial or failure to
comply
Š In 5% of cases other types of malaria
Š Two-thirds of cases occur in people of African
or South Asia ethnic origin and over half of the cases
occur in those who had been visiting friends and
relatives (VFRs) in endemic areas.
Š Most patients with falciparum malaria
acquire infection in Africa: West Africa is the commonest
geographical source.
Š Most Plasmodium vivax infections are acquired in
South Asia.
Malaria
Š The minimum incubation period for falciparum is 6
days. Most present in the first month, almost all present
within 6 months Approximately three-quarters in the UK
& ROI are caused by Plasmodium falciparum, which is
capable of invading a high proportion of red blood cells
and rapidly leading to severe or life-threatening multiorgan
disease.
Vivax or ovale infections commonly present
after 6 months and may be delayed for years.
Diagnosis of Malaria
Š Three thick and thin blood slides is still
the gold standard in diagnosis but P.
falciparum can be diagnosed almost as
accurately using rapid diagnostic tests
(RDTs) which detect plasmodial antigens or
enzymes
Š RDTs are not as reliable for other
Plasmodium species.
Symptoms of malaria
Š No specific symptoms
Š Most patients complain of fever, headache and
general malaise. Gastrointestinal disturbances,
jaundice or respiratory symptoms occasionally
occur and are often responsible for
misdiagnosis.
Š Thrombocytopenia is highly suggestive of
malaria in all kinds of malaria
Who gets malaria….
Two-thirds of cases occur in people of African
or South Asia ethnic origin and over half of the cases
occur in those who had been visiting friends and relations
(VFRs) in endemic areas. Immunity lost rapidly
Most patients with falciparum malaria
acquire infection in Africa especially West Africa.
Most Plasmodium vivax infections
are acquired in South Asia.
Backpackers, younger tourists, adventure trailers at risk
FATALITIES THE BIG THREE
ŠHEART ATTACK
ŠINJURY - ACCIDENTS
ŠINFECTIONS ( only 1%)
CVS
Accident
Vehicle accidents per 100
million kilometers
Š
Š
Š
Š
Š
Š
Š
Š
Š
Take accident rate in Finland as 1.0
Rate in UK is 0.9
ROI is 1.7
Europe: north 3.0 east 5.0
Spain 5.3
South Africa >10.0
Turkey 20.0
Kenya 41.0
Egypt 44.0 ……….No figures for India
Travel Medicine includes
Š Preventive and curative
medicine in all areas related to
the travelling public before and
after travel
Š Screening, diagnosis and
treatment of immigrants from
countries of different ethnic
origin and where diseases not
associated with Ireland are
endemic.
Š Some working knowledge of
travellers rights and
responsibilities and of our
rights and responsibilities in
2
relation to them
Recognizing Travel Medicine as a
special entity
Š Australia, N Zealand, South Africa now
Hungary(2006) demand training in
Travel medicine before granting y fever
license
Š This can be possession of a Certificate
in Travel Medicine, proof of
attendance at a Course or other
Europe
Š Each country has started some sort of Travel
Health Society usually based on existing
organizations that were once totally devoted
to Tropical Medicine
Š For example Irish Soc Travel Med, The
College of Nursing Travel Health Forum,(UK)
National Travel Health Network (UK) ,Health
Protection Scotland,British Travel Health
Associatioin, The Swedish Soc for Tropical
Medicine, the Norwegian Forum for Travel
Medicine, The Danish Soc Travel Medicine
etc ..
6
Š Helsinki NECTM 2008 May 21-24
North America
The International Society of Travel
medicine based in Stone Mountain
Georgia
Š Brings all groups together, produces
a regular Journal of Travel
Medicine and runs a biannual
international scientific
conference.
Š Also operates Geosentinal an email service based on information
from participating members world
wide. ( Note that the French send
Lettre d’informations santevoyages )
7
Certificate in Travel
medicine
Becoming a requirement in some countries
e.g. Australia, South Africa
CERTIFICATE EXAM IN TRAVEL HEALTH
(IRELAND) held in RCSI and run
in conjunction with the Irish Soc Tr Medicine
Next date Oct 2006. Fee €250. Open to all health
care professionals
Travel Health Course RCSI/ISTM €500 (€400 for
ISTN members) March 2008
International transport carries
diseases of all kinds
Š
Š
Š
Š
Infectious agents, vectors, rodents all come
along especially by ship
Aedes Aegypti has appeared in countries
where it was previously eliminated. Asian A
albopictus recently arrived in the USA Dengue
has spread to all warmer climates.
Mosquitoes, flies, cockroaches -20% 15%
and 50% respectively carried to China by air,
land and sea in 2003 !
Four aircraft carrying rodents originated in
Saudia ,Japan, Russia and Hong Kong
Don’t forget runway and airport malaria..even 8
suitcase malaria!.
The Irish Experience
Central Statistics Office Dublin 2006
These statistics tell us that
4.8 million people took trips
abroad from Ireland in 9
months Jan-Sept 2005 of
these 226,000 went to
developing countries
British stats tell us that up to 40%
of these were VFRs
( visiting friends and relatives)
IRISH Surveys 1999 and
2005
Š 400 000 Irish adults visited a
designated ‘at risk’ country
between 1996 - 1999
Š Numbers have significantly
increased since 2000 as you can
see from CSO figures
(Aer Rianta)
10
IRISH SURVEY 1999
Š Of those surveyed Africa was nominated as a
risk area (66%), India was first for 27% and
malaria and snakes as a risk for most
even when not a real risk
Š Virtually no one talked about Turkey (cluster
of cholers Sept 2005 8 Belgian tourists),
Morocco , Tunisia, Egypt or Mexico
Š Only one in ten knew that hepatitis A could
be contacted by contaminated water
Š Six in ten associated malaria and mosquitoes
and typhoid and water
11
IRISH SURVEY 1999/
2005
Š
Š
Š
Š
Š
Š
Š
Non Vaccinated - REASONS as per cent
Is not important
28
No time
8
Brief visit
8
Travel Agent
4
Complacency
4
No real reason
44
13
Numbers of Irish
vaccinated very low
Š Only 7% of those visiting North
Africa
Š Only 25% ( one in 4.0) visiting
sub-saharan Africa
Š Only 20%( one in 3.5) visiting
Thailand, India, Malaysia,
Š Only 6% of those visiting Turkey
Š Only 4% of those visiting Tunisia
14
2005 Feb Dublin Airport..have you any malaria
tablets with you going to a malaria country?
NO
75%
YES
25%
Why not?
Don’t take tablets when
22
nothing wrong with me
Mosquitos don’t bite
10me
The disease is not
6
dangerous
Cost
1
Allegeric
1
Malaria prevention
does not work 1
Side effects
75%
1
Other
24
Don’t know
23
Not stated
25%
17
No
Yes
Have You Malaria Tablets?
(Base: Malaria Sample= 199)
Of those who said YES
What are they for?
Prevention
Stand by emergency
treatment
78
6
12
Both
No Reply
75%
No
4
25%
Yes
3.
Is giving vaccines a piece of
cake?
Š
Š
Š
Š
Š
Š
Š
Š
Phone Calls
Shopping around
Come back sick
Time consuming
Outlay
Knowledge base - up to date
Reactions real imagined
Register with HSE
Typical reaction to
tetanus - the more
often it is given the
worse the reaction
Patients Information
and Misinformation
Lonely
Planet
Rough
Guide
Newspapers
Travel
Agent
Internet
Hearsay
Family
doctor
Travel
clinic
TV
programs
17
Information….
ISTM.IE Irish Soc Travel medicine on the web
with 4 different linked sites.
To join contact [email protected]
Newsletter gives Courses / Seminars/ Exams
Travax (normally £250/year. Members of ISTM ge
for €30 !!) WHO, CDC, MD Travel Health,
CSO and Dept of Health and Children
International Society,
Books: WHO ‘blue book’
A Primer of Travel Medicine Colbert 2005
Travel Chart updates 3 times a year
a few simple questions
• Do I give polio all the time to
every traveller ?
• Is it OPV or IPV. What are the real
differences?
• Is polio likely to be contracted by
the traveller?
Global campaign started in 1988
By 2003 no of
Countries endemic
reduced
from 125 to 6.
BY mid 2004 polio
Had returned to 22
countries of which
10 had been free
the previous
Year!
Is one mosquito repellent better
than another?
Does lariam really cause
hallucinations?
What abut garlic, vitamin B and
homeopathic medicine?
Can I take an OCP and doxycycline?
Should I give hep A vaccine to
children?
Is diamox any good?
What should I charge?
• What about ID versus IM rabies?
• Is Japanese encephalitis a real
risk? if so where?
• What about Hep B?
Thank you for your attention
QuickTime™ and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
QuickTime™ and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
QuickTime™ and a
TIFF (Uncompressed) decom
are needed to see this pictu
QuickTime™ and a
TIFF (Uncompressed) decompressor
are needed to see this picture.