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Practice & Communication of Science What is Science? What is Science About? Formally speaking… “the intellectual and practical activity encompassing the systematic study of the structure and behaviour of the physical and natural world through observation and experiment” (Google definition) Somewhat less formally… intellectual and practical – thinking and doing systematic study – organised, thorough structure and behaviour – what things are and do physical and natural – non-living and living observation and experiment – passive vs active What is Science About? Most informally… “Accounting for variation” Why accounting? We are aiming to explain rather than describe Why variation? my personal definition We are surrounded by variation in… structures (entities, things) and their behaviour (changes in relation to each other) Variation in structure/behaviour underpins everything Accounting for that is what science is about Variation in Structure/Behaviour is Everything Take vision… Relies on light propagation and objects in world behaving differently by virtue of their structures Relies on chemical/electrical variation/behaviour “If objects were entirely transparent they would be invisible” (R Tallis – The Kingdom of Infinite Space) Light’s interaction with visual pigments Na+ and K+ diffusion, ATP hydrolysis Myelin insulating properties, protein ion channel Above all, vision characterised by change Things do not ‘happen’ unless things ‘change’! The Aim of Science To explain the largest number of natural phenomena with the fewest principles That is the ‘direction’ that science moves in But it often seem to get more complicated! As our knowledge base increases Global scientific output doubles every 9 years (Nature newsblog, May 07 2014) Accumulation of detail precedes ‘collapse’ into explanation Petabytes of LHC data Higgs Boson Darwin’s years of observation Natural Selection The Aim of Science To predict the future, and thereby change it Is beef safe to eat? Will this drug cure this disease? What does it mean if I have this set of genes? What will happen if CO2 continues to rise? Science recognises itself as a ‘work in progress’ it is driven by ignorance The Role of Ignorance in Science Ignorance plays a critical role in science “The fuel on which science runs is ignorance. Science is like a hungry furnace that must be fed logs from the forests of ignorance that surround us. In the process, the clearing that we call knowledge expands, but the more it expands, the longer its perimeter and the more ignorance comes into view. . . . A true scientist is bored by knowledge; it is the assault on ignorance that motivates him - the mysteries that previous discoveries have revealed. The forest is more interesting than the clearing.” Matt Ridley. Genome: the autobiography of a species in 23 chapters, p 271 (1999) “Science is the belief in the ignorance of experts” R Feynman, American Scientist v87, p462 (1999) The Provisional Nature of Science What science can know is incomplete in both theory and practice Theoretical limits of knowledge… Plato’s cave Scientific Revolution – circa 17th century on Our view of reality as but shadows on a cave wall Success suggested determinable universe Kant’s Critique of Pure Reason (1781) ‘thing-in-itself’ unknowable; only things as they appear (phenomena) The Provisional Nature of Science Theoretical limits of knowledge… 20th Century shocks Quantum theory Gödel's Incompleteness Theorems Indeterminacy, randomness a feature of reality All complex logical systems are incomplete “…doomed also, as a result, is the ideal of science to devise a set of axioms from which all phenomena of the external world can be deduced” CB Boyer, A History of Mathematics (1991) Seems irrelevant to our day-to-day lives, but… How can we be 100% sure that… things will work tomorrow the way they did today? things will work over there as they do here? The Provisional Nature of Science Practical limits of knowledge… Observations are incomplete and error-prone So, all scientific interpretations are fallible This is a strength of science! It discourages dogma “Science alone of all the subjects contains within itself the lesson of the danger of belief in the infallibility of the greatest teachers in the preceding generation.” R Feynman, American Scientist v87, p462 (1999) Major shift occurred around 1600 Scholasticism Modern Science Studying existing knowledge accumulation of evidence (ie beginnings of the Scientific Method) The Provisional Nature of Science Scientific interpretations are falsifiable Science is the current ‘best guess’, open to being disproved; it is falsifiable “…we shall have to get accustomed to the idea that we must not look upon science as a ‘body of knowledge’, but rather as a system of hypotheses, or as a system of guesses or anticipations that in principle cannot be justified, but with which we work as long as they stand up to tests, and of which we are never justified in saying we know they are ‘true’” K Popper (1902-94), The Logic of Scientific Discovery Assertions that are not falsifiable are not scientific Bertrand Russel’s cosmic teapot burden of proof on the proposer, not us! Bottom Line Scientific thinking can be counter-intuitive incomplete, limited, provisional, fallible, ignorance involves lots of rigorous data-handling but “science a tribute to what we can know although we are fallible” J Bronowski, AoM, 1976 And give me Science over Superstition any day!