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Magnetic Resonance Imaging Can you imagine being treated for a high fever, racking cough and pneumonia without a chest x-ray? It has taken 34 years, many scientists and clinicians worldwide to develop prostate MRI for clinical use. Prostate MRI was introduced into the North American healthcare system only few years ago. Can you imagine being diagnosed or treated for prostate cancer without your doctor being able to see it? The current practice of PSA Screening Trans Rectal Ultrasound (TRUS) schematic biopsy is inaccurate and misses one third of the prostate cancers that cause serious illness and frequently diagnoses non-aggressive cancers which cause no harm. That is what we were doing! GE Finally, for the first time in medical history the prostate can be seen in anatomic and functional detail with TRUS Schematic biopsy non aggressive cancer aggressive cancer TRUS/MRI Fusion Targeted biopsy Biopsy Welcome to the advanced new world of MRI accurate diagnosis treatment and monitoring of prostate cancer prostate TRUS/MRI fusion targeted biopsy usually diagnoses the aggressive cancers at the initial biopsy session avoiding repeat biopsy sessions and biopsy complications. When aggressive prostate cancers are diagnosed Prostate MRI becomes key in treatment selection and planning. rectum The MRI Exam Prostate MRI takes 40-50 minutes. The MRI unit may surround you to your chin, vibrates and is noisy. A small injection of Buscopan and Gadolinium are given. Buscopan can cause a dry mouth and difficulty voiding after the exam. A cold sensation may occur with the Gadolinium injection. Patients with poor kidney function can not have Gadolinium. MRI examines the prostate in 3 different detailed parameters – external and internal anatomy, cell density and micro blood vessels. Imaged are all the pelvic organs – prostate, bowel, bladder, bones, large blood vessels and lymph nodes. You may not be able to have a prostate MRI if you have moving metal body parts or are claustrophobic. Prostate MRI A Major Advancement o Evaluates men at risk of prostate cancer o Locates and characterizes cancer nodules o Selects/limits the number of men requiring biopsy o Precision TRUS/MRI fusion targeted biopsy earlier diagnosis and treatment Accuracy Prostate MRI is 90% accurate in diagnosing aggressive prostate cancer when the MRI exam is of high quality, the report clinically useful, experienced radiologist, MRI knowledgeable urologist and a pathologist to provide proof of the presence of cancer from tissue samples. prostate o Local-regional staging o Decreases overdiagnosis of non-aggressive cancers and unnecessary treatment o Active surveillance criteria and monitoring o More accurate treatment selection and planning (Focal Therapy, Surgery, Radiation) cancer nodule o Post-treatment evaluation for residual or recurrent cancer Learn more o An imaging biomarker An evolving major advancement in prostate cancer management American Urological Association White paper, online, 2017 Prostate Cancer Imaging App, iTunes, 2016 An interactive imaging course teaching radiologist and urologist how to read and interpret Prostate MRI Philippe Puech, M.D., Lille, France o Updates Prostate Cancer Classifications, Predictor Tables and Risk Stratifications for doctors AUA Standard Operating Procedure for MRI of the Prostate, for patients PCAMRI.com, 2017 Prostate Cancer Accurate Diagnosis and Treatment 21 Educational Pamphlets For Patients And Curious Doctors Samuel Aronson, M.D., Montreal, Canada This pamphlet is available free online PCAMRI.com