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Cecilia Trucchi
Department of Health Sciences
(DiSSal)
University of Genoa
Via A. Pastore, 1
16132 Genoa (Italy)
Genoa, 25/08/2015
Dear Editor,
We wish to submit a new manuscript entitled “Methodological criticisms in the evaluation of
Pneumococcal Conjugate Vaccine effectiveness” for consideration by the Journal of
Preventive Medicine and Hygiene.
We confirm that this work is original and has not been published elsewhere nor is it
currently under consideration for publication elsewhere.
In this paper, we discuss the variability in available estimates in Low Respiratory Tract
Infections (LRTIs) and associated risk factors, and the methodological criticism in their
evaluation. This is relevant in the light of the gradual introduction of PCV13 immunization
strategy targeted to elderly and risk groups in middle-high income countries. We think that
the paper should be of interest to readers in the areas of epidemiology and Public Health
immunization strategies.
We declare that Prof. Filippo Ansaldi has received research fundings as investigator or
principal investigator and has participated at speaker’s bureaus and advisory board
meetings sponsored by Pfizer, Sanofi Pasteur and GSK. Dr. Cecilia Trucchi and Chiara
Paganino have no conflict of interest.
No other relationships/conditions/circumstances that present a potential conflict of interest
exist.
Thank you for your consideration of this manuscript.
Sincerely,
The Authors
Cecilia Trucchi, Chiara Paganino and Filippo Ansaldi