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1613, either, cat. 57 NONINVASIVE ANALYSIS OF STROKE VOLUME VARIABILTY BY RECORDING OF CARDIAC MECHANICAL VIBRATIONS ON THE CHEST K. Tavakolian1, A.P. Blaber2, H.K. Symonds3, A. Akhbardeh4, W. Lee5, B. Kaminska6 1 Engineering Science, 2Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 3Fraser Health Authority, Burnaby, BC, Canada, 4School of Medicine, Johns Hopkins University, Baltimore, MD, USA, 5Burnaby General Hospital, 6Engineering Science, Simon Fraser University, Burnaby, BC, Canada Seismocardiography, SCG, is a method to record the mechanical vibrations created by heart beating from the sternum, noninvasively. In this study an integrative approach is presented to provide surrogate measures for beat-by-beat stroke volume variability using SCG. Recordings of suprasternal pulsed Doppler was used as the reference method for comparison. For each beat the stroke volume was determined by multiplication of the area under the curve on the Doppler signal (stroke distance) with the area of the aortic ring, LVOT. Morphological features were extracted from SCG signal based on current knowledge of the correspondence of SCG waves to cardiac events. Nonlinear methods were used to process these SCG features to produce an estimate the stroke volume. For the control group eight healthy young subjects were selected and the preliminary results, analyzed using Bland and Altman method, showed that in 95% of the heart beats the stroke volume estimated by SCG was in a 7.5 mL range of the Doppler values. As our abnormal group we have considered ten cardiac patients from the healthy heart program at Burnaby General Hospital who had low ejection fractions. Recent studies have shown that analysis of stroke volume variability can provide information about the inotropic state of the myocardium while the older method of heart rate variability, HRV, provides us with knowledge of the chronotropic state of myocardium and ventricular performance. SCG can provide us with an inexpensive alternative method of monitoring of the cardiac contractility in relation to electrocardiography.