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- - Identification and characterization of virulence factors and determinants from bacteria of the Burkholderia cepacia complex and their exploitation to identify potential targets for therapeutic intervention; Identification and characterization of small non-coding regulatory RNAs from Burkholderia cepacia complex; Molecular characterization of microbial populations of environmental and medical interest; Biochemistry, molecular biology and physiology of exopolysaccharide biosynthesis by gram-negative bacteria; Exploitation of the nematode Caenorhabditis elegans as an infection model to identify bacterial virulence determinants.