Download Constitutional Law - Mercer University

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

Document related concepts

Pharmacogenomics wikipedia , lookup

Genetic engineering wikipedia , lookup

Human genetic variation wikipedia , lookup

Genetic testing wikipedia , lookup

Medical genetics wikipedia , lookup

Designer baby wikipedia , lookup

Genome (book) wikipedia , lookup

Public health genomics wikipedia , lookup

Transcript
Contemporary Ethical
Dilemmas
Jody Blanke
Distinguished Professor of Computer
Information Systems and Law
Mercer University
Ethical Dilemmas
 An ethical dilemma arises in
situations where a choice must be
made between unpleasant
alternatives
 Ex. Should I choose life knowing an
unborn child will be born with severe
disabilities?
 Ex. Should I adhere to my spouse’s
wishes not to be placed on a respirator?
Noteworthy Historical Events
58,000 to 68,000 BC
 Neanderthal Burial Sites
 Evidence of belief in an afterlife
1932–1972
 Tuskegee Study of Syphilis study
1933–1945
 Holocaust
1946 - Military Tribunal for War Crimes
 Nuremberg Code
1949 – International Code of Medical Ethics
1954 – Guidelines on Human Experimentation
– The First Kidney Transplant
1960s – Cardiopulmonary resuscitation –
prolonging life beyond what was reasonably
expected
1964 – WHO guidelines for medical doctors
conducting biomedical research
– Declaration of Helsinki is the basis for
advanced clinical practices today
1968 – Harvard Ad Hoc Committee on
Brain Death
1970 – Patient as a Person
1971 – Kennedy Institute of Ethics
established
1972 – Informed consent – reasonable
man standard
1973 – Right to Abortion
– Roe v. Wade
1974 – National Research Act
– created the National Commission
for the Protection of Human Subjects of
Biomedical and Behavioral Research
1975 – First successful cloning of frogs
1976 – Karen Ann Quinlan case
– First living will legislation enacted
1978 – Commission for the Study of Ethical
Problems in Medicine
1980 – Hemlock Society formed to
advocate for physician-assisted dying
1983 – California passes first durable
power of attorney legislation
1990 – Patient Self-Determination Act
– Nancy Cruzan case
– Dr. Kevorkian assists terminally ill
patients in suicide
– Derek Humphry publishes Final Exit
1994 – Oregon’s Death with Dignity Act
– Michigan - assisted suicide illegal
1996 – HIPAA
– Cloning of Dolly
1997 – Dr. Kevorkian charged with murder
– Supreme Court – “laboratory of the
states”
1999 – Dr. Kevorkian convicted of murder
2001 – President’s Council on Bioethics
created
– U.S. Attorney General’s failed
attempt to challenge Oregon's Death
with Dignity Act
2003 – Human gnome system fully
sequenced
2007 – Supreme Court blocks Bush
administration’s attempt to punish
doctors who prescribe drugs in Oregon
Abortion
 Many interests
 Rights of the Woman
 Autonomy
 Rights of the Fetus
 Rights of the Spouse
 Rights of the State
 Protecting life
Abortion
 Many ethical questions
When does life begin?
Who decides?
Who protects the unborn fetus?
What are the rights of the child or woman
who has been raped?
 What are the rights of the spouse?
 What are the religious implications?
 When does control over one’s body begin,
and when does it end?




Roe v. Wade (1973)
 Woman’s right to privacy
 Recognition of state protecting the unborn
 First Trimester: abortion decision between
woman and physician
 Second Trimester: state may reasonably
regulate abortion procedure
 Third Trimester: state may prohibit all
abortions except those deemed necessary to
protect maternal life or health
Planned Parenthood v. Casey (1992)
 Reaffirmed a woman’s right to an abortion
 Rejected Roe v. Wade’s trimester approach
 Reaffirmed the state’s power to restrict abortions after
fetal viability as long as the rule does not impose an
undue burden
 It is not an undue burden





To require that a woman be informed of the nature of the
abortion and of the risks involved
To be provided with information about alternatives
To require informed consent before the procedure
To require parental consent for a minor (as long as there is
a judicial bypass option)
To require a 24-hour waiting period
Funding
 Denial of Financial Assistance for Elective
Abortions
 Funding Not Required for Therapeutic
Abortions
 Funding Bans Unconstitutional in
California
 Funding Discrimination Prohibited in
Arizona
 Refusal to Fund Abortion Counseling Not
Unconstitutional
Spousal Consent
 Husband’s Interest Insufficient
 Husband’s Required Consent
Unconstitutional
Eugenic Sterilization
 Buck v. Bell (1927)
 Supreme Court approved of sterilization
of the mentally deficient and
feebleminded
 Wade v. Bethesda Hospital (1971)
 Supreme Court reversed its position
Negligent Sterilization
 The improper performance of
sterilization may result in lawsuits
based on such theories as
 wrongful birth
 wrongful life
 wrongful conception
Wrongful Birth, Wrongful Life,
Wrongful Conception
 These case have generally not be
successful on claims for the costs of raising
normal healthy children
 Some claims have been successful
regarding




Additional medical costs
Pain and suffering
Lost wages
Damages associated with children born with
genetic defects
Artificial Insemination
 Homologous artificial insemination
 semen of spouse used to impregnate
 Heterologous artificial insemination
 semen from donor other than husband
 additional issues regarding consent and
confidentiality
Surrogacy
 Method of reproduction whereby a
woman agrees to give birth to a child
for another party
 Surrogate may be
 child’s genetic mother
 gestational carrier
Ethical and Legal Issues
 Legal right to enter a surrogacy
contract?
 Parental rights of commissioning
couple?
 Long-term effect of surrogacy
contracts?
 Psychological impact on child?
Organ Donations
 Federal regulations require
 protocols regarding an organization’s
organ procurement responsibilities
 specific notification duties
 requirements informing families of
potential donors
 Who lives? Who dies? Who decides?
Research, Experimentation,
and Clinical Trials
 Ethical considerations







Honesty
Integrity
Autonomy
Self-determination
Hippocratic maxim of do no harm
Justice
How to fairly conduct blind trials
Nuremberg Code and
Declaration of Helsinki
 International Code of Ethics
 governs human research
 Result of Nazi medical atrocities
 Requires human subjects be fully
informed
Food and Drug Administration
 Regulates the conduct of clinical trials
 Approval of a new drug often costs
much money and takes much time
 But, FDA must be cautious
 Ex. thalidomide
Institutional Review Board
 Federal regulations require hospitalbased Institutional Review Boards
(IRB)
 IRB Functions
 review proposed research studies
 approve protocols for research
 conduct research oversight
Informed Consent
 Organizations must
 Fully disclose to the patient the inherent
risks, benefits, and treatment
alternatives
 Determine competency of the patient to
consent
 Obtain written consent from the patient
Genetic Information
Nondiscrimination Act (GINA)
 Law prohibits discrimination on basis of genetic
information with respect to the availability of
health insurance and employment
 Prohibits group health plans and insurers from
denying coverage to a healthy individual based
on genetic predisposition to develop a specific
disease
 Prohibits employers from using genetic
information when making hiring, firing, job
placement, or promotion decisions
Genetic Markers
 A genetic marker is a gene or DNA
sequence that has a known location
on a chromosome and can be
associated with a particular gene or
trait
 Genetic markers can identify certain
diseases
Stem Cell Research
 Use of embryonic stem cells to create
organs and various body tissues
 Highly controversial issue generally
involving religious beliefs
 Concerns as to how far scientists
might go in their attempt to create
AIDS
 Deadliest epidemic in human history
 First case appeared in literature in 1981
 More than 35 million people have died
from AIDS
 Can be spread by direct contact with
infected blood or bodily fluids
Disclosure of Physician’s
HIV Status
 Physician cut his hand during a surgical
procedure
 Question about whether his blood contacted
patient’s open surgical incision
 Physician tested positive for HIV
 Pennsylvania Supreme Court held that a
compelling need existed for at least partial
disclosure
 Patients were not given physician’s name, but
were told of the potential risk
 “The welfare of the people is the supreme law”