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UNIT B: Human Body Systems Chapter 8: Human Organization Chapter 9: Digestive System Chapter 10: Circulatory System and Lymphatic System Chapter 11: Respiratory System: Section 11.2 Chapter 12: Nervous System Chapter 13: Urinary System Chapter 14: Reproductive System UNIT B Chapter 11: Respiratory System Chapter 11: Respiratory System In this chapter, you will learn about the structure and function of the respiratory system. How would a narrowing and swelling of the airways affect the respiratory volumes? How do the typical treatments for asthma work to reduce the symptoms? Asthma is a disease in which the airways become constricted (narrowed) and inflamed (swollen), both of which can result in difficulty breathing. It is one of the most common chronic diseases in children. It is estimated that 10 to 15 percent of children in Canada have asthma. TO PREVIOUS SLIDE Why is it so difficult to develop a cure for asthma? What are some of the normal defence mechanisms of the respiratory tract? UNIT B Chapter 11: Respiratory System 11.2 Mechanism of Breathing A free flow of air is vitally important during ventilation (breathing). A spirometer is a device used to record the volume of air inhaled and exhaled with each breath. TO PREVIOUS SLIDE Section 11.2 UNIT B Chapter 11: Respiratory System Section 11.2 Figure 11.7 Measuring ventilation. A spirometer measures the air inhaled and exhaled with each breath. During inspiration, the pen moves up. During expiration, the pen moves down. Vital capacity (red) is the maximum amount of air a person can exhale after taking the deepest inhalation possible. TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Respiratory Volumes Tidal volume: the amount of air that is inhaled and exhaled at rest TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Inspiratory reserve volume: the additional volume of air that can be inhaled beyond the tidal volume (e.g., during deep breathing) Expiratory reserve volume: the addition volume of air that can be exhaled beyond the tidal volume TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Vital capacity: the maximum volume of air that can moved in and out during a single breath • Vital capacity = tidal + inspiratory reserve + expiratory reserve TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Residual volume: amount of air that remains in the lungs and airways after a full exhalation • During normal breathing, only 70% of tidal volume reaches the alveoli; about 30% remains in the airways. This air is not useful for gas exchange because it has been depleted of oxygen. TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Respiratory volumes depend on various factors. • Age (decreasing after age 30) • Gender (10-20% lower in women) • Physical activity (20-30% higher in conditioned athletes) • Respiratory disorders o Some disorders decrease vital capacity or can increase residual volumes because the individual has difficulty emptying the lungs TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Inspiration and Expiration To understand ventilation, the following facts should be remembered: • There is a continuous column of air from the pharynx to the alveoli in the lungs. • The lungs lie within the sealed-off thoracic cavity. o Rib cage: top and sides of the thoracic cavity o Intercostal muscles: lie between the ribs o Diaphragm and connective tissue: floor of the thoracic cavity • The lungs adhere to the thoracic wall through the pleura. o Space between the two pleurae is minimal due to surface tension of the fluid between them TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Inspiration Inspiration is the active phase of ventilation. • Diaphragm: contracts and lowers • Intercostal muscles: contract • Rib cage: moves up and out • As the thoracic volume increases, the lung volume increases, and air pressure in alveoli decreases o Alveolar pressure is lower than atmospheric pressure outside lungs, causing air to flow into airways TO PREVIOUS SLIDE Section 11.2 UNIT B Chapter 11: Respiratory System Expiration Expiration is the passive phase of ventilation. • Diaphragm: relaxes and moves up • Intercostal muscles: relax • Rib cage: moves down and in • As the thoracic volume decreases, the lung volume decreases, and air pressure in alveoli increases o Alveolar pressure is higher than atmospheric pressure outside lungs, causing air to be pushed out TO PREVIOUS SLIDE Section 11.2 UNIT B Chapter 11: Respiratory System TO PREVIOUS SLIDE Section 11.2 Figure 11.8 Inspiration and expiration compared. a. During inspiration, the thoracic cavity and lungs expand so that air is drawn in. b. During expiration, the thoracic cavity and lungs resume their original positions and pressures. Now, air is forced out. UNIT B Chapter 11: Respiratory System Section 11.2 Control of Breathing Ventilation is controlled by a respiratory centre in the medulla oblongata of the brain. • Stimulates inspiration by automatically sending impulses to the diaphragm through the phrenic nerve, and to the intercostal muscles through the intercostal nerve Figure 11.9 Nervous control of breathing. The respiratory centre automatically stimulates the external intercostal (rib) muscles and diaphragm to contract via the phrenic nerve. After forced inhalation, stretch receptors send inhibitory nerve impulses to the respiratory centre via the vagus nerve. Usually, expiration automatically occurs because of the lack of stimulation from the respiratory centre to the diaphragm and intercostal muscles. TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Section 11.2 Control of Breathing • When the respiratory centre stops sending signals to the diaphragm and rib cage, the diaphragm relaxes and expiration occurs • Following inhalation, stretch receptors in the alveolar walls send inhibitory nerve impulses via the vagus nerve to the respiratory centre, which inhibits the respiratory centre from sending impulses TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System Control of Breathing Chemical Input • The respiratory centre is also sensitive to levels of carbon dioxide and hydrogen ions in the blood o When carbon dioxide or hydrogen ion concentrations increase, the respiratory centre increases rate and depth of breathing • Respiration rate is also influenced by cells called carotid bodies and aortic bodies o When concentration of blood oxygen decreases, these bodies signal the respiratory centre to increase rate and depth of breathing TO PREVIOUS SLIDE Section 11.2 UNIT B Chapter 11: Respiratory System Section 11.2 Check Your Progress 1. Compare tidal volume and vital capacity. 2. Explain why inspiration is considered the active phase of ventilation, and expiration the passive phase. TO PREVIOUS SLIDE UNIT B Chapter 11: Respiratory System TO PREVIOUS SLIDE Section 11.2 UNIT B Chapter 11: Respiratory System TO PREVIOUS SLIDE Section 11.2