Download Probing Prokaryotic Social Behaviors with Bacterial Lobster Traps

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

Document related concepts

Hospital-acquired infection wikipedia, lookup

Sociality and disease transmission wikipedia, lookup

Infection wikipedia, lookup

Neonatal infection wikipedia, lookup

Biofilm wikipedia, lookup

Metagenomics wikipedia, lookup

Transmission (medicine) wikipedia, lookup

Triclocarban wikipedia, lookup

Traveler's diarrhea wikipedia, lookup

Gastroenteritis wikipedia, lookup

Infection control wikipedia, lookup

Trimeric autotransporter adhesin wikipedia, lookup

Human microbiota wikipedia, lookup

Bacterial cell structure wikipedia, lookup

Bacterial morphological plasticity wikipedia, lookup

Magnetotactic bacteria wikipedia, lookup

Marine microorganism wikipedia, lookup

History of virology wikipedia, lookup

Bacteria wikipedia, lookup

Urinary tract infection wikipedia, lookup

Horizontal gene transfer wikipedia, lookup

Anaerobic infection wikipedia, lookup

Skin flora wikipedia, lookup

Transcript
The survival of pathogens in the human body has been rigorously studied for well over a
century. Bacteria are able to colonize, persist and thrive in vivo due to an array of
capabilities, including the ability to attach to host tissues, produce extracellular virulence
factors, and evade the immune system. Most bacterial pathogenesis studies have
focused on mono-culture infections; however, it is clear that many bacterial infections
are not simply the result of colonization with a single species, but rather ensue from the
actions of polymicrobial communities. Microbes within polymicrobial infections often
display synergistic interactions that result in enhanced colonization and persistence in
the infection site, although the molecular processes controlling these synergistic
interactions are generally not known. Here, I will discuss how interactions between
biofilm bacteria impact community development, resistance to host innate immunity, and
in vivo persistence. I will also discuss the use of novel technologies for probing bacterial
interactions in small biofilm populations.