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بشرى جبار. د Medical Biology Lecture 3 CONECTIVE TISSUE( PART/ 2) Loose Ordinary Connective Tissue Loose connective tissue (LCT) is literally found everywhere in the body, as filling between apposed body parts. It is also called areolar tissue. It consists of both fibrous extracellular molecules and a number of different cell types. In whole mount spreads of areolar tissue the extracellular fibers are very evident. Collagen, a tough, supporting fiber, appears as wide pink stained bundles, where as elastin fibers appear as thin black line (Areolar Tissue). Within these spreads the predominant cell type, the fibroblast, is also observed. In sections, LCT contains obvious collagen bundles, fibroblasts, and capillaries with their associated pericytes (Loose Connective Tissue). The "open"areas in this micrograph are filled with the amorphous matrix molecules, glycosaminoglycans and proteoglycans. LCT matrix molecules also exist within organs providing support for the resident cells. These fibers, reticular fibers, are arranged in a mesh-like arrangement through organs (Reticular Fibers). Elastin fibers are also found in many organs, and with special stains are visible in a "ribbon candy" morphology (Elastin Fibers) Adipose Tissue Adipose or fat tissue is the padding of the body. It is organized into groups of cells called lobules which are separated by بشرى جبار. د Medical Biology Lecture 3 collagenous and reticular connective tissue septa (Adipose Tissue). In the formation of a fat cell the cell produces numerous lipid containing vesicles which fuse into one large intracellular lipid droplet. The cell (Adipocyte) becomes so full of lipid that the nucleus and other cellular organelles become compressed into a small crescent of cytoplasm . Blood consists of red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes), which are tiny pieces of bone marrow cell. Plasma also contains water, salts, sugars, lipids, and amino acids. Blood is approximately 55 percent plasma and 45 percent formed elements. Blood transports substances from one part of the body to another and plays an important role in the immune system. dense connective tissue Also known as fibrous connective tissue. It has a matrix of densely packed collagen fibers. There are two types of collagen: regular and irregular. The collagen fibers of regular dense connective tissue are lined up in parallel. Tendons, which bind muscle to bone, and ligaments, which join bones together, are examples of dense regular connective tissue. The strong بشرى جبار. د Medical Biology Lecture 3 covering of various organs, such as kidneys and muscle, is dense irregular connective tissue. Cartilage (from the Latin, meaning “gristle”) is a connective tissue with an abundant number of collagen fibers in a rubbery matrix. It is both strong and flexible. Cartilage provides support and cushioning. It is found between the discs of the vertebrae in the spine, surrounding the ends of joints such as knees, and in the nose and ears. Bone Bone is a rigid connective tissue that has a matrix of collagen fibers embedded in calcium salts. It is the hardest tissue in the body, although it is not brittle. Most of the skeletal system is comprised of bone, which provides support for muscle attachment and protects the internal organs.