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Cancer Sources: Huntsman Cancer Institute American Cancer Society What is Cancer? • Cancer is the general name for a group of more than 300 diseases. • Cancer is when cells grow out of control. (unorganized and mutated cells) • Untreated cancer can cause serious illness and death. • Cancer has the ability to spread. Normal Cells • The body is made up of trillions of living cells. • Normal cells grow, divide, and make new cells and die in an orderly way. • In early years of life, normal cells divide rapidly to allow a person to grow. • In adulthood, most cells only divide to replace worn-out or dying cells or repair injuries. How Cancer Starts • Cancer starts when cells in a part of the body start growing out of control. This can form a tumor. • Instead of dying, cancer cells continue to grow and form new, abnormal cells. • Cancer cells can also grow into other tissues, something normal cells can’t do. • Can spread. healthy organized cell structure disorganized cancer cell structure Cells become cancer cells due to damage in cell DNA. All Cancer Is Genetic: Starts in the genes of the cell. • DNA damage is caused by mistakes that happen when a cell is reproducing. • DNA damage can also occur from an exposure from the environment. (smoking, sun exposure (radiation), chemical exposure, viruses, bacteria) What Causes Cancer? Damage to DNA Radiation Some viruses and bacteria Certain chemicals All Cancer is Genetic • Cancer starts in the genes of a cell. • Not all cancer is inherited. Genetic Inherited How Cancer Spreads • Cancer cells often travel to other parts of the body where they grow and form new tumors. • This happens when the cancer cells get into the bloodstream or lymph vessels. • This process is called metastasis. Cancer Growth 1 million cells = Pinhead 2-6 weeks 2-6 weeks 2-6 weeks 9 2-6 weeks 1 billion cells = Small grape How Cancers Differ Different types of cancer can behave differently. For instance, lung cancer and skin cancer are very different diseases. They grow at different rates and respond to different treatments. This is why people with cancer need treatment that is aimed at their kind of cancer. Tumors that are not cancer • A tumor is an abnormal lump or collection of cells. • Not all tumors are cancer. • Tumors that are not cancer are called benign. • Benign tumors can cause problemsbut are seldom life threatening. Finding Cancer • Treatment works best when cancer is found early. (while cancer is small, less likely to have spread) • Sometimes, it’s possible to find cancer before experiencing problems. As you age it is recommended that you have cancerrelated check-ups and tests to detect cancer early. (breast cancer, prostate cancer, colon cancer) How common is cancer? 50% of men 33% of women Will develop cancer during their lifetime. Anyone can get cancer at any age. The risk of developing most types of cancer can be reduced by changes in lifestyle. • Stay away from tobacco • Limit your time in the sun • Avoid tanning beds • Be physically active • Eat healthy foods • Do proper self tests or schedule doctor check-ups How Is Cancer Treated? Dandelion • Pull it out • Burn it • Apply weed killer • Block the sun, prevent watering • Strengthen surrounding grass or improve the soil • Replace patches of lawn Cancer • Surgery • Radiation Therapy • Chemotherapy • Hormonal Therapy • Biological/Immuno therapy • Stem Cell Transplant/Bone Marrow Transplant Survival Rates for Cancer • Today, more than 14.5 million people alive in the U.S. have survived some type of cancer. • Every year more and more people survive cancer. • Early detection makes survival rates go up. Can you prevent cancer? NO, but you can do things to lower your risk. Limit alcohol consumption • Drinking alcohol is linked to a higher risk of certain types of cancer. • It’s the amount of alcohol drunk over time which seems to be the factor most significant in raising cancer risk. • No more than 2 drinks per day for men and 1 drink per day for women. Avoid smoking • The combined use of alcohol and tobacco raises the risk of mouth, throat, voice box, and esophagus cancer far more the effects of either alone. • Many cancers can be prevented if people don’t use tobacco. • Smoking damages nearly every organ in the human body and accounts for 30% of all cancer deaths. • Ex smokers have less cancer than people who continue smoking. Smoking There is no safe level of exposure to tobacco smoke. Any exposure to tobacco smoke – even an occasional cigarette or exposure to secondhand smoke – is harmful. - US Surgeon General Smoking increases risk of these cancers: sinuses, nose, lip, mouth, throat, lung, esophagus, pancreas, cervical, ovaries, kidney, bladder, stomach, colorectal, leukemia. It Is Your Decision You Know The Consequences • Health • Environment • Social • Financial • Addiction cycle is not fun • Tobacco companies target you to get you to try smoking 20 What Can I Do If Someone I Care About Uses Tobacco? • Tell them how you feel • Support and encourage them to quit, even if they have tried many times • Avoid secondhand smoke and try to protect yourself from breathing the smoke • Ask them to call 1-800-QUIT-NOW to get help quitting Diet • Eat a lot of fresh vegetables and fruits • Choose whole grains rather than refined grains and sugars • Limit red meats (beef, pork, lamb) • Limit processed meats (bacon, deli meat, hot dogs) • Eat recommended serving sizes each day Ultraviolet (UV) Rays and Sun Exposure • It’s important to protect ourselves from developing skin cancer. Because Utah is at a high elevation (closer to the sun) we need to protect ourselves from UV rays. • You should always use sun screen (SPF of 30 or higher). Re-apply frequently when doing outdoor activities. • Wear hats, sunglasses, and clothes that cover your skin. • Do not use tanning beds or sun lamps. Who Is at Risk for Skin Cancer? Everyone! 24 Factors that Increase Risk for Skin Cancer Main risk factor is exposure to UV radiation Other risk factors ♦ Blue, green or gray eyes ♦ Freckle or burn easily ♦Family history ♦ Many moles ♦ Fair skin ♦ Blond or red hair ♦ Blistering sunburns as a child Use tanning beds Live at a high altitude Work outside or do a lot of outdoor activities The Sun and You •The sun triggers Vitamin D synthesis, which is good for the body •Only SMALL amounts of sunlight are needed (10-15 minutes; NOT a suntan) •Vitamin D is found in foods such as eggs, fish, and cheese Cancerquest.org Main Types of Skin Cancer • Squamous Cell Carcinoma • Basal Cell Carcinoma • Melanoma Squamous Cell Carcinoma • Accounts for over 20% of all skin cancers in the U.S. • Slow growing but more likely to spread than basal cell carcinoma Warning Signs • Crusted or scaly red patch of skin with irregular borders • A growth with an indentation in the center that may bleed • Open sore that bleeds or crusts and doesn‘t heal • Wart-like growth that may crust and bleed Lower lip & rim of the ear are especially at risk Basal Cell Carcinoma Most common type of skin cancer in the U.S. Local destruction Rarely spreads Warning Signs • • • • • Shiny bump that is pearly or translucent Pink growth with a crusted indentation in the center Open sore that bleeds, oozes, or crusts, and doesn't heal A reddish patch or irritated area. It may crust, itch or hurt Scar-like area which is yellow, white or waxy Usually occurs on the face, eyelids, ears, scalp, shoulders, and back Melanoma • Most serious type of skin cancer • Starts in the melanocytes • 4% of all skin cancers in the U.S., but causes 79% of skin cancer deaths • If it is not caught early it can easily spread ABCDEs of Melanoma Asymmetry Border Color Diameter Evolution Dear 16 year old me… The Dangers of Tanning Beds Using a tanning bed, even once, during your lifetime may increase your risk of melanoma by 75% 35 Sunscreen • Blocks both UVA and UVB rays • Sun Protection Factor (SPF) of 30 • Apply 20 minutes before going outside • Reapply every 2 hours • Apply generously 36 Twins... Darrick Antell, M.D., F.A.C.S. What can I do to lower my risk of developing cancer? • Don’t use tobacco • Limit alcohol consumption • Protect yourself from sun exposure and do not use tanning beds • Avoid sugary drinks • Limit red meat intake and avoid processed meat • Limit salt consumption • Eat a mostly plant based diet • Maintain a healthy body weight through physical activity • Get recommended cancer screenings Because you don’t want to end up looking like this... 39