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MOLECULAR BIOLOGY I: DNA Replication 2.28.07 molecular biology DNA replication Central dogma Nuclear genome Mitochondrial genome Base pairing Template strand Complementary strand Antiparallel helix Origin of replication Ori Helicase Single stranded DNA binding protein DNA polymerase Primase RNA primer RNAase Replication fork Leading strand Lagging strand Ligase Proofreading Excision repair Mismatch repair MOLECULAR BIOLOGY II: RNA synthesis 3.2.07 RNA Uracil Ribose Gene mRNA rRNA tRNA Transcribed region of a gene Promoter Un-(or non-) transcribed region of a gene TATA box Transcription factor Sequence-specific DNA binding protein Initiation complex Chromatin Histones Splicing Exon Intron Alternate splicing Gene expression MOLECULAR BIOLOGY III: Translation and molecular genotype 3.5.07 Protein Translation Genetic code Triplet code Codon Redundant but not ambiguous Coding region of mRNA Non-coding region of mRNA 5’UTR 3’UTR (5’) cap poly A tail Translation initiation codon tRNA Anticodon Charged tRNA Uncharged tRNA Ribosome rRNA Small subunit of ribosome Large subunit of ribosome AUG Stop codon Translation termination miRNA Nonsense mutation Missense mutation Frameshift mutation Silent mutation
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