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SCHOOL OF CHEMICAL, BIOLOGICAL & MATERIALS ENGINEERING The University of Oklahoma Norman, Oklahoma 2004 – 2005 Seminar Series CBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBME CBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBMECBME DR. WARREN D. SEIDER PROFESSOR DEPARTMENT OF CHEMICAL AND BIOLMOLECULAR ENGINEERING UNIVERSITY OF PENNSYLVANIA PHILADELPHIA PENNSYLVANIA Will present a seminar on “A GAME THEORETIC APPROACH TO MULTI-OBJECTIVE PROCESS DESIGNS” A method of designing processes that are inherently safe is introduced. In cases where safety is not threatened (e.g., in isothermal fermentation reactors), but product compositions can rapidly degrade, this method provides designs that insure high product quality (e.g., in pharmaceuticals processes). Using game theory, the method accounts for the tradeoffs in profitability, controllability, safety and/or product quality, and flexibility. For nonlinear processes that are hard to control, that is, have an unstable and/or non-minimum phase steady state, over a wide range of operating conditions, extended bifurcation diagrams (EBDs) are introduced. When a steady state is non-minimum-phase, the process may exhibit inverse response. The steady states of processes are classified on the basis of instability and non-minimumphaseness to segregate the operating regimes into distinct zones. Local optimal designs, one corresponding to each zone, are obtained first. These are compared with other local optimal designs at alternate operating conditions, and/or process reconfigurations, to obtain the global optimal design using game theory. Four indices, profitability, controllability, safety and/or product quality, and flexibility, characterize the optimality of a design. A novel index for safe operation and/or product quality at a steady state is formulated as a function of the eigenvalues of the Jacobian of the process model and the Jacobian of the process zero dynamics, both evaluated at the steady state, providing a quantitative measure of instability and non-minimum phase behavior. The application of the proposed method to an isothermal continuous stirredtank reactor (CSTR) with van der Vusse reactions, an exothermic CSTR, and an anaerobic fermentor with substrate and product inhibition, is presented. THURSDAY, MARCH 3, 2005 COOKIES AND COFFEE -- 2:30 P.M. SEMINAR -- 3:00 P.M. SARKEYS ENERGY CENTER, ROOM M-204 THIS IS A REQUIRED SEMINAR FOR CHE 5971