Download G. Date and author of revision of data sheet

V1.0
Data sheet for genetically modified lines
(GM – strained or non-strained) or strained mutants
Articles 23 and 28 Animal Experiments Ordinance (TVV)
A.
Decision of cantonal authority
Decision of cantonal
authority
on constraint and further
breeding of the line
(Art. 127 Animal Welfare Ordinance TSchV)
Line subject to clarification (no decision of cantonal authority)
Non-strained line (no decision of cantonal authority)
Strained line - decision of cantonal authority enclosed:
Date:
B.
Number
maximum degree of stress:
Study director / owner of animal line
Study director /
owner of the line (of the
local population)
Surname, first name,
institute, address, e-mail,
phone
C.
Details of laboratory animal husbandry
C1
Licence number of
laboratory animal
husbandry
(if necessary, licence according to Art. 142 TSchV, Form-G:
C2
Husbandry manager
Surname, first name
Address, e-mail, phone
C3
Location of animal
husbandry
Address
D.
Basic scientific data
D1
Animal species
D2
Name of line
(Nomenclature according
to:
http://www.informatics.jax.o
rg/mgihome/nomen/ )
Mai 2011
(Art. 114 TSchV)
(Annex 2 TVV)
)
D3
Genetic modification
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Type of GM
Database reference
Literature details
Purpose of line
D4
Production

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
Producer
Method of production
Year of production
Number of generations
Status of breeding
(ongoing, stopped,
cryo-preserved)
D5
Genotype
 Genotype
 Genetic background
 Hygiene status
E.
Summary of monitoring of constraint (Annex 3 TVV)
E1
Status of monitoring of
constraint
still subject to clarification
still subject to clarification / stress provisionally reported
completed, not strained
completed / constraint definitively reported; decision of authority pending
completed / strained line according to decision of authorities (cf. chapter A)
E2
Record of constraint
 Scope of observations
conducted
 Comparison of mortality
and reproduction data
with those of wild type
E3
Phenotype
Maximum effective degree of severity (retrospective):
 Description of the
phenotype and the
constraint
 Assessment of constraint
 Degree of severity and
age of occurrence
 Expression of transgene
(dominant/recessive,
conditional, inducible)
E4
Mitigation of constraint
 specific needs
 strain-reducing measures
and their expected
impact
p. 2 / 3
E5
Criteria for withdrawal
 Euthanasia of strained
individuals
F.
Remarks
G.
Date and author of revision of data sheet
Date
Author
Contents / reason for revision
p. 3 / 3