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UNIVERSITY OF KENT 1 2 3 4 5 6 7 8 9 MODULE SPECIFICATION TEMPLATE The title of the module: PH800 Biomedical Optics The Department which will be responsible for management of the module: SPS The level of the module (M); The number of credits which the module represents: 15 (7.5 ECTS) Which term(s) the module is to be taught in (or other teaching pattern): 2nd term Prerequisite and co-requisite modules: PH504, PH604, PH513 or equivalent if the student comes from a different university The programmes of study to which the module contributes: PG qualification The intended subject specific learning outcomes introduce students to the concepts of propagation of light into the tissue, optical imaging methods with emphasis on confocal microscopy and on white light interferometry for optical coherence tomography; give students the necessary theoretical background for the successful completion of their research programme. On successful completion of the module students will have: a) an understanding of the interaction of low power optical waves with the tissue; b) a comprehensive understanding of the principles of white light interferometry applied for imaging tissue; c) knowledge and understanding of principles of fluorescence, adaptive optics, confocal microscopy and optical coherence tomography applied in imaging the eye and the skin; d) knowledge of optical sources for high resolution OCT; e) engineering of signal processing. The intended generic learning outcomes: Capability to develop and conduct independent research on optics applied for non-invasive optical imaging; ability to successful complete a thesis (Master or PhD) or a shorter research project (3-10 months). A synopsis of the curriculum Title Number of Lecturer lectures Introduction into tissue optics (absorption, scattering, anisotropy, therapeutic window), 3 Adrian Podoleanu reflectance spectrometry, fluorescence, safety), optical properties of the tissue Elements of histopathology 1 John Schofield, Maidstone and Tunbridge Wells NHS Trust Photodynamic therapy, contrast media, ICG angiography 1 Pearce Keane Confocal microscopy (CM) principles 4 Adrian Podoleanu OCT in ophthalmology 2 Pearce Keane, UCL Institute of Ophthalmology and Moorfields Eye Hospital CM in dermatology and biology Adrian Podoleanu Principles of Optical Coherence Tomography (OCT), relation between the linewidth and 6 Adrian Podoleanu depth resolution, large bandwidth sources, source correlation function, configurations of flying spot OCT systems Nanoparticles as contrast agents for CM, OCT, toxicity, measurements of their 1 Vladimir Gubala, School of Pharmacy concentration Imaging the nervous system with OCT 2 Gurprit Lall, School of Pharmacy UNIVERSITY OF KENT Signal processing in Longitudinal and en-face OCT Coherence radar Channelled spectrum and spectral OCT Swept source OCT Broadband lasers for OCT (elements of supercontinuum) Configurations of optical path difference scanning, Combining OCT with CM Noise in CM and in OCT Polarisation and dispersion in CM and OCT Adaptive optics for enhanced transverse resolution in CM and OCT Photorefractive surgery, CM and OCT in imaging the cornea 10 11 1 1 1 1 2 1 2 2 3 1 Adrian Podoleanu Adrian Podoleanu Adrian Podoleanu Adrian Podoleanu Ole Bang, Technical University of Denmark Adrian Podoleanu Adrian Podoleanu Sylvain Rivet, University of Brest Adrian Podoleanu Ranjan Rajendram, UCL Institute of Ophthalmology and Moorfields Eye Hospital Fred Barnes, School of Computing Peter Lee, Engineering and Digital Art Elements of graphic cards for OCT signal processing 2 Elements of field programmable arrays (FPGA) for OCT signal processing 2 Total: 39 Learning and Teaching Methods, including the nature and number of contact hours and the total study hours which will be expected of students, and how these relate to achievement of the intended learning outcomes There are more than 36 lectures. Each lecture will require an extra number of literature search hours and documentation which will amount to a total of 150 hours. Teaching methods include lectures and presentations of videos specially acquired for this course. Assessment methods and how these relate to testing achievement of the intended learning outcomes Formal unseen written examination by the end of the course: 70%, course work: one assessment 10% and one essay 20%. Convenor: Adrian Podoleanu, Professor of Biomedical Optics