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UNIVERSITY OF KENT
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MODULE SPECIFICATION TEMPLATE
The title of the module: PH800 Biomedical Optics
The Department which will be responsible for management of the module: SPS
The level of the module (M);
The number of credits which the module represents: 15 (7.5 ECTS)
Which term(s) the module is to be taught in (or other teaching pattern): 2nd term
Prerequisite and co-requisite modules: PH504, PH604, PH513 or equivalent if the student comes from a different university
The programmes of study to which the module contributes: PG qualification
The intended subject specific learning outcomes introduce students to the concepts of propagation of light into the tissue, optical imaging methods with
emphasis on confocal microscopy and on white light interferometry for optical coherence tomography; give students the necessary theoretical background for
the successful completion of their research programme. On successful completion of the module students will have:
a) an understanding of the interaction of low power optical waves with the tissue;
b) a comprehensive understanding of the principles of white light interferometry applied for imaging tissue;
c) knowledge and understanding of principles of fluorescence, adaptive optics, confocal microscopy and optical coherence tomography applied in imaging the
eye and the skin;
d) knowledge of optical sources for high resolution OCT;
e) engineering of signal processing.
The intended generic learning outcomes:
Capability to develop and conduct independent research on optics applied for non-invasive optical imaging; ability to successful complete a thesis (Master or
PhD) or a shorter research project (3-10 months).
A synopsis of the curriculum
Title
Number of Lecturer
lectures
Introduction into tissue optics (absorption, scattering, anisotropy, therapeutic window),
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Adrian Podoleanu
reflectance spectrometry, fluorescence, safety), optical properties of the tissue
Elements of histopathology
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John Schofield, Maidstone and Tunbridge
Wells NHS Trust
Photodynamic therapy, contrast media, ICG angiography
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Pearce Keane
Confocal microscopy (CM) principles
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Adrian Podoleanu
OCT in ophthalmology
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Pearce Keane, UCL Institute of
Ophthalmology and Moorfields Eye Hospital
CM in dermatology and biology
Adrian Podoleanu
Principles of Optical Coherence Tomography (OCT), relation between the linewidth and
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Adrian Podoleanu
depth resolution, large bandwidth sources, source correlation function, configurations of
flying spot OCT systems
Nanoparticles as contrast agents for CM, OCT, toxicity, measurements of their
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Vladimir Gubala, School of Pharmacy
concentration
Imaging the nervous system with OCT
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Gurprit Lall, School of Pharmacy
UNIVERSITY OF KENT
Signal processing in Longitudinal and en-face OCT
Coherence radar
Channelled spectrum and spectral OCT
Swept source OCT
Broadband lasers for OCT (elements of supercontinuum)
Configurations of optical path difference scanning, Combining OCT with CM
Noise in CM and in OCT
Polarisation and dispersion in CM and OCT
Adaptive optics for enhanced transverse resolution in CM and OCT
Photorefractive surgery, CM and OCT in imaging the cornea
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Adrian Podoleanu
Adrian Podoleanu
Adrian Podoleanu
Adrian Podoleanu
Ole Bang, Technical University of Denmark
Adrian Podoleanu
Adrian Podoleanu
Sylvain Rivet, University of Brest
Adrian Podoleanu
Ranjan Rajendram, UCL Institute of
Ophthalmology and Moorfields Eye Hospital
Fred Barnes, School of Computing
Peter Lee, Engineering and Digital Art
Elements of graphic cards for OCT signal processing
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Elements of field programmable arrays (FPGA) for OCT signal processing
2
Total:
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Learning and Teaching Methods, including the nature and number of contact hours and the total study hours which will be expected of students, and how
these relate to achievement of the intended learning outcomes
There are more than 36 lectures. Each lecture will require an extra number of literature search hours and documentation which will amount to a total of 150
hours. Teaching methods include lectures and presentations of videos specially acquired for this course.
Assessment methods and how these relate to testing achievement of the intended learning outcomes
Formal unseen written examination by the end of the course: 70%, course work: one assessment 10% and one essay 20%.
Convenor: Adrian Podoleanu, Professor of Biomedical Optics