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How to Perform a First Rate Diastology Exam Jill A Odabashian RDCS, FASE Cardiovascular Imaging Core Clinical/Research Sonographer Heart and Vascular Institute Cleveland Clinic Disclosure • Speaker Bureau for GE Healthcare Objectives • Components and technique for performing a diastolic exam • Including right sided diastology exam • Proper Doppler display • Respiratory variation • Incorporate maneuvers • TDI • Recognize diastolic abnormalities 1 Great Reference Publication date: 2008 How Do We get Diastolic Dysfunction? • Happens with aging • LVH • Most cardiac diseases • Pericardial Constriction • Results in increased filling pressures Who Should Have a Diastolic Assessment? • CAD • Conduction system disorder • Hypertensive Heart disease • Heart transplant rejection • Diabetes • Constrictive pericarditis • Obesity/Metabolic syndrome • Drug related cardiac toxicity • Chronic renal failure • Diabetes • Cardiomyopathies (HCM, DCM, ICM) • Chronic renal failure • Valvular heart disease • Infiltrative Disorder (amyloid) amyloid) • Sleep Apnea 2 Diastology is part of the echo exam • Includes left heart evaluation • Essential for all CHF pts • HTN • Nearly 50% of pts with HF have normal or near normal global systolic function • Almost half of the pts presenting to ED with acute HF have diastolic dysfunction • Diastolic dysfunction is often overlooked Sonographers Diastolic Assessment • Establish a routine • Starts when meeting the pt and asking questions • Note HT, WT (BSA), HR, BP, rhythm, hemodynamics • Hx of HTN, HF • Dyspnea (walking down the echo hallway) • Patient in wheelchair • SOB (lying flat on the echo table) • Requires O2 (during echo exam) Sonographers Diastolic Assessment cont. • Get the facts • Pt history • Previous echo or other imaging exams • Indication for echocardiogram QuickTime™ and a Cinepak decompressor are needed to see this picture. • Explain procedure… procedure…echo exam may take a few minutes longer 3 Back to Basics • Clean ECG signal (tap electrodes to confirm) • Good voltage, big R wave (change lead), no artifact • Place electrode over diaphragm and others close to heart (in case respirometer is needed) Look For Doppler Clues Quality PW Doppler Exam • SemiSemi-transparent spectral • Decrease Doppler gains • Clean/sharp edges for reproducibility • Optimize scale E A • Sample volume (SV) will vary • Use respirometer if E/A velocities vary beat to beat or effusion is present (a fib exception) 4 LV/MV Inflow Measurements • Peak E and A velocities • E wave Decel Time (DT) • E/A ratio • LV/MV IF and atrial duration E A AD 100 sweep speeds for measuring Observe and acquire at 50 sweep speed SV Placement and Size Affects Peak E/A Velocity E E A A E wave at MV tips 1.0m/sec A wave close to MV 0.2m/sec PERFECT! E wave close to MV 0.5m/sec A wave close to MV 0.2m/sec SV Placement and Size Affects Peak E/A Velocity SV too far away from MV tips SV too close to MV annulus E E E A PERFECT! A A 70 cm/sec 50 cm/sec 60 cm/sec 5 Atrial Fibrillation • No A wave present • Capture / acquire / measure 33-6 beats Respirometer Tips • • • • • Practice breathing technique with pt If needed optimize respirometer gain to observe peaks and valleys Deeper breathing Keep ECG and respirometer close together for timing Sweep speed (25(25-50) slower to better assess respiratory variation Observe septal motion during deep inspiration and expiration QuickTime™ and a Cinepak decompressor are needed to see this picture. SV placement at MV leaflet tips SV size 11-2cm 6 Valsalva Maneuver • If E wave > A wave perform valsalva maneuver • Valsalva maneuver on average should be held for at least 12 seconds to help differentiate between stages • Temporarily alters hemodynamics During valsalva maintain cursor and SV placement (use 2D update) Annotate on screen An adequate valsalva maneuver should have 20% decrease in E wave velocity Color MM-mode LV Filling Flow Propagation Velocity (Vp (Vp)) Early Filling Measure along first aliasing velocity Late Filling 4cm • Two components are present: early and late diastolic filling velocities velocities within the LV • Slope represents the speed of ventricular inflow • Not affected by loading conditions 7 Color MM-mode A4C Early Filling Measure along first aliasing velocity Late Filling 4cm Normal > 45cm/sec • Optimize image depth (14(14-16cm) • Shift color Doppler baseline shift upwards 3030-40cm for best aliasing • Size color sector (annulus to annulus) to cover entire LV chamber chamber (MV to apex) including 1/3 of LA • Maximize color frame rate • Adjust color gain to just below saturation • Cursor parallel to inflow (red/yellow diastolic inflow) • 100 sweep speed for measuring • Vp slope of 1st aliasing velocity from MV opening to 4cm into LV Pulmonary Vein • A5C, A2C, A3C • RUPV most common • Color guided (decrease color scale to 30 if not seen) • SV size 33-4mm • Placement 0.50.5-1cm into vein (avoid junction of LA/PV) S D • Sweep speed 50 assessment • Measure 100 sweep speed • Atrial fibrillation (collect 3 - 6 beats) A Avoid junction of LA/PV PV with contrast enhancement, try holding breath 8 Tissue Doppler Imaging (TDI) • Newer diastolic indexes for assessing filling pressures regardless of loading conditions • Optimize depth 16cm • Sweep speed 5050-100 • Evaluate filling pressures E/e’ E/e’ TDI Limitations • Irregular rhythm • Translational and rotational motion • Angle dependent SV size 5mm Activate color TDI, reduce 2D gain s’ e’ a’ PW SV placement on septal/medial septal/medial and lateral MV annulus add TV annulus (practice with ROI with translation) Ventricular systolic evaluation (S wave) Optimize scale 1010-15cm/s (increase scale will be noisy) 9 Using E/e΄ E/e΄ to Estimate LV Filling Pressures Ratio <8 8 – 15 >15 Formula LVIF 100 Average TDI 8 100/8 = 12.5 LVEDP Low/NL Mod High LVIF 100 cm/sec Formula Average TDI 8 cm/sec If LA pressures are elevated, then MV inflow pattern is affected Formula Velocity Ratios LVIF 100 Average TDI 8 Normal LA pressures E/e’ <8mmHg 100/8 = 12.5 High LA pressures E/e’ >15mmHg LVIF 100 cm/sec Formula Average TDI 8 cm/sec e' Who Should Have a Right Heart Diastolic Exam? Right heart evaluation must be included: • Constrictive disease • Right heart failure • Differentiate COPD from constrictive disease Add: • IVRT • RV inflow • Respirometer • Hepatic vein flow • SVC vein flow 10 (IVRT) Isovolumic Relaxation Time • Between A4C and A5C view • Measuring time between AV closure and MV opening • Cursor between AV and MV • CW (increase filter) • PW (SV 33-4/low filter) 1 cm above AV in LVOT • Achieve AV closure click and MV opening click • Sweep speed 50 measure 100 sweep speed IVRT TV/RV Inflow • Repeat same measures as MV/LV inflow • Assess TR velocity in all views • Prepare for best Doppler alignment by moving RV image to center of sector • Optimize Doppler scale • 50 sweep speed for assessment • 100 sweep for measuring • Up to 35% respiratory variation is normal. • Use respirometer if E/A velocities vary beat to beat or effusion is present (a fib exception) E A TV/RV Inflow Observe septal motion during deep inspiration (does it bow to the left?) QuickTime™ and a Cinepak decompressor are needed to see this picture. SV placement at TV leaflet tips (try not crossover LV) SV size 11-2cm 11 IVC • Subcostal view • Proximal diameter of IVC (normal 2.1cm) • Optimize depth • IVC should collapse 50% with inspiration QuickTime™ and a Microsoft Video 1 decompressor are needed to see this picture. Collect and capture sniff test by 2D QuickTime™ and a Microsoft Video 1 decompressor are needed to see this picture. QuickTime™ and a Microsoft Video 1 decompressor are needed to see this picture. Practice (check respirometer) respirometer) Utilize mm-mode Hepatic Vein Doppler • Subcostal SAX • Index 12 o’ o’clock • PW SV size 33-4mm • Color guided SV placement 22-3cm into HV from IVC junction • Normal HV are sometimes difficult to obtain VR AR S D 12 Hepatic Vein Doppler Cont. ~15% respiratory variation is normal PW SV size 33-4mm Assess at 50 sweep speed Measure 100 sweep speed Superior Vena Cava Doppler • Pt supine, no pillow, chin up, head tilt to left • Right supraclavicular fossa • Index marker 10 o’ o’clock Superior Vena Cava Doppler • Color guided PW placement 5cm into SVC • Check respirometer • SV size 33-4mm • Sweep speed 50 (shows ~5 beats) • Measure 100 sweep speed QuickTime™ and a Microsoft Video 1 decompressor are needed to see this picture. AR VR D S 13 Other Helpful Maneuvers • Unmask the A wave • Change preload • Sitting • Standing • Raise legs • Isometrics • Maintain SV placement by using 2D update Use 2D update and annotate position on screen LV, LA, RA Volumes • Optimize depth and zoom on each chamber separately • A4C, A2C obtain biplane measurements • LV EDV/ESV • Planimeter atria at endend-systole (just before MV/TV opens • Extra attention to LA size • Largest LA / RA size • LAVI = LA Volume / BSA 14 Why Volumes to Assess Diastolic Dysfunction? • Assess the ability of the LV to fill to a normal EDV without abnormal increase of the EDP at rest and with exercise • Failure to increase LV EDV and maintain CO2 with exercise 2009 ASE/EAE Guidelines and Standards 15 Great Reference Publication date: 2008 Thank You 16