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Table number NATIONAL UNIVERSITY OF SINGAPORE EXAMINATION ST1232 STATISTICS FOR LIFE SCIENCES (Semester 1 : AY 2011-2012) November 2011 - Time Allowed: 2 Hours _________________________________________________________________ INSTRUCTIONS TO CANDIDATES 1. This examination paper contains FOUR (4) multiple-choice questions, and FOUR (4) structured questions. The examination paper comprises FOURTEEN (14) printed pages. 2. Candidates must answer ALL questions. For the multiple-choice questions, each correct answer will be awarded 3 marks, whereas one mark will be deducted for each incorrect answer. No marks will be awarded or deducted if the option (e) is selected as the answer for any of the questions. The mark allocated for each part of the structured question is shown in brackets. The total mark for this paper is 60. 3. Candidates may use programmable calculators and may bring one handwritten A4-size help sheet, written on both sides. 4. This is a CLOSED BOOK examination. 5. Please enter the answer to each question in the space allocated in the question sheet. 6. Write down your matriculation number in the space below, and your table number at the top right hand corner of the page. Matriculation No: ___________________________ Question 1-4 5 6 7 8 Marks scored Max. marks Total 12 10 8 16 14 (60) 1 ST1232 Questions 1-4 [12 marks] a. Probability that the data support the null hypothesis, given the alternative hypothesis is actually correct b. Probability that the data support the alternative hypothesis, given the null hypothesis is actually correct c. Probability that the null hypothesis is actually correct, given the data support the alternative hypothesis d. Probability that the alternative hypothesis is actually correct, given the data support the null hypothesis e. I don’t know Question 2. Which of the following statements is true? a. The larger the sample size, the greater the standard error of the estimated parameters b. The more categories you want to have in a nominal categorical variable, the larger the sample size needed to draw an inference with the same precision c. As sample size decreases, so does the size of the confidence interval for the parameter d. Listing the individuals in Singapore by ethnic group and choosing a proportion from within each ethnic group at random is an example of simple random sampling e. I don’t know Question 3. What will happen (all things remaining equal) to a confidence interval if you calculated a 99 percent confidence interval rather than a 95% confidence interval? a. It will be narrower b. The width will not change c. The sample size will increase d. None of the above e. I don’t know Question 4. Which of the following statements is true? a. A Type II error is the failure to reject a false null hypothesis b. Assuming innocence until “proven” guilty, a Type I error occurs when a truly guilty person is found to be innocent c. In two independent tests, if the P-value of test A is 0.001 and the P-value of test B is 0.01, then the effect size observed in A is necessarily bigger than the effect size observed in B d. When the P-value is < 0.05, this indicates that the null hypothesis is likely to be true e. I don’t know Q1 Ans: 2 Q2 Ans: Q3 Ans: Q4 Ans: ST1232 Question 5. [10 marks] Norton and Dunn carried out a case-control survey in 1985 on snoring behavior in relation to the presence or absence of heart disease. In a summarized version of their survey, subjects were categorized as either non-snorers or snorers, which were charted according to reports by the subjects’ spouses. Heart Disease No Heart Disease Total Snorers 86 1,019 1,105 An analysis with SPSS yielded the following output. 3 Non-snorers 24 1,355 1,379 Total 110 2,374 2,484 ST1232 Question 5. (10 marks) On the basis of the analyses, investigate the belief that snoring is associated with heart disease onset, stating what the appropriate null and alternative hypotheses are. Answer to Question 5 to be written below: 4 ST1232 Question 6. [8 marks] The time taken for a drug therapy to take effect in the body is often vital in deciding the best treatment to assign for a patient in a critical condition. There are two competing drugs in the market, and a clinical trial has been performed across two separate groups of 50 individuals to investigate the time-to-effect for these two treatments. The data from the clinical trial measure the time taken in minutes for each treatment to be effective. These data were subsequently analysed by a junior statistician, who produced the following output: 5 ST1232 6 ST1232 Based on the output, comment on whether there is any difference in the time-to-effect for these two treatments. (8 marks) Answer to Question 6 to be written below: 7 ST1232 Question 7. [16 marks] A study into the time taken to complete a 100 metre sprint by male and female athletes was conducted. The data originated from 25 races which were held once every two years across a span of 50 years from 1960 to 2008. Question 7a. (5 marks) On the basis of the scatterplot figure above (ignoring the dashed and dotted regression lines for the time being), comment on how the time taken to complete 100 metres has changed over the years. Answer to Question 7a to be written below: 8 ST1232 Question 7b. (8 marks) A local newspaper reporter took a look at the scatterplot and added the two regression lines (dashed and dotted) as shown in the figure. He went on to report that from the year 2050 onwards, female athletes are expected to complete the 100 metre sprint in a shorter time than male athletes. Comment on the overall suitability of the regression lines and the validity of his report. Answer to Question 7b to be written below: 9 ST1232 Question 7c. (3 marks) A junior analyst with a local newspaper attempted to explain the relationship between the timespan (year) and the time taken to complete the 100 metre sprint. Based on the scatterplot, she decided to fit a regression model adjusting for gender, and produced the following analysis: Parameter Intercept Gender-male Year Beta Std. Error P-value 69.783 -1.195 -0.029 5.207 0.076 0.003 1.1 10-17 2.0 10-20 8.7 10-17 95% Confidence Interval Lower Bound Upper Bound 59.370 80.196 -1.346 -1.044 -0.035 -0.024 Comment on the validity of this analysis, in light of the scatterplot figure seen earlier. Answer to Question 7c to be written below: 10 ST1232 Question 8. [14 marks] A survey on the salary of 52 tenure-track professors was performed in 1972 to investigate whether there were any evidence of discrimination. The following information is available: Variable name sex rank year degree years_degree salary Description Coded 0 for female and 1 for male Current professorial rank of the person, one of: Assistant, Associate or Full Professor Number of years in current rank Highest degree, whether Doctorate or Masters Number of years since the highest degree was earned Annual salary, in dollars A plot of the salary by gender is shown below: Question 8a. (3 marks) Comment on the figure above, specifically focusing on whether there is any evidence of gender discrimination. Answer to Question 8a to be written below: 11 ST1232 Question 8b. (3 marks) A multivariate regression model is fitted to the data, and the following output is generated: Parameter Beta Std. Error P-value Intercept rank-associate rank-full year degree-masters years_degree sex-male 16912 5292 11119 476 1389 -125 -1166 816 1145 1352 95 1019 77 926 1.2 10-24 3.2 10-5 1.6 10-10 8.7 10-6 0.180 0.115 0.214 95% Confidence Interval Lower Bound Upper Bound 15280 18545 3002 7583 8415 13822 286 666 -649 3426 -280 30 -3018 685 On the basis of the analysis above, what is the evidence that male academics on average are paid more than the female equivalent? Answer to Question 8b to be written below: Question 8c. (4 marks) On the basis of the cross-tabulation table below on the distribution of academics by their rank and gender, explain what may have explained the disparity between the figure in (a) and the output seen in (b). Female Male Assistant 8 10 Associate 2 12 Answer to Question 8c to be written below: 12 Full 4 16 ST1232 Question 8d. (4 marks) An associate professor is interested to investigate whether there was any significant difference in the salaries of associate versus the full professors. Are the analyses performed thus far adequate to address whether there is any difference in the salary of an associate professor when compared to a full professor of the same gender and experience? If so, comment whether there is any difference. Answer to Question 8d to be written below: 13 ST1232 ANSWER CHECKLIST To help ensure that you have answered all the relevant questions, the boxes below remind you of the number of parts each question has. You are welcome to tick the boxes to indicate you have completed the relevant parts of each question. You will not be penalized for not ticking the boxes. Question 1 (3 marks) Question 2 (3 marks) Question 3 (3 marks) Question 4 (3 marks) Question 5 (10 marks) Question 6 (8 marks) Question 7a (5 marks) Question 7b (8 marks) Question 7c (3 marks) Question 8a (3 marks) Question 8b (3 marks) Question 8c (4 marks) Question 8d (4 marks) ~~~ END OF PAPER ~~~ 14