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Network Based Approaches to Studying Ebola and Emerging Infectious Diseases in Real-time Using Smartphones Solomon Abiola, MS CHET/DSAIL Outline Rationale and background mHealth and the application of Node to Ebola Network based approaches to combat disease 2 Twitter: eWizard2_0 www.oneabitech.com Mobile health and big data among the current most hyped technologies in 2014 3 Source: Gartner Twitter: eWizard2_0 www.oneabitech.com The rapid growth of mobile technology allows it to serve as the perfect health platform Why mobile health? There are over 334 million smartphones projected to be present in Africa in 2017 ~ 30% of the continent’s population How can we use mobile health? Remote assessments, diagnostics, increase access to care, disease modeling, etc. 4 Source: TechCrunch Twitter: eWizard2_0 www.oneabitech.com Objective real time geospatial modelling via smartphone sensors improves contact tracing 5 Twitter: eWizard2_0 www.oneabitech.com The Princeton University pilot allowed us to geospatially identify infectious disease sinks Main Application Page Source: Pilot Study Twitter: eWizard2_0 www.oneabitech.com Areas highly susceptible to interaction among students with the application appear darker. (Aerial Map of Princeton University) Node enables health workers and practioners to see incidents in real time Two user interactions sampled from March 17th, 2015 Twitter: eWizard2_0 www.oneabitech.com The Node study is designed to recruit a small subpopulation in Lagos, Nigeria Through our preparatory activities we’re expecting at least 100 participants (>40 University of Lagos + > 25 Nigerian Institute of Medical Research + >40 A/B testers) Enroll up to 100 individuals within Lagos state (city population over 21 million) Participants will be paid 50 USD equivalent in phone credits per month of completion during the study 8 Twitter: eWizard2_0 www.oneabitech.com Knowledge Discovery Process has lead to interesting insights in mHealth for disease mHealth App Node ~70 users Parse (Facebook) Google CartoDB PHASE 1 Twitter: eWizard2_0 www.oneabitech.com MongoDB ~30GB AWS PHASE 2 PHASE 3 Analytics ~2mb PHASE 4 9 The Node View platform allows for real time health action based on ubiquitous data Locate Identify View Enact Lagos, Nigeria Beta Test Twitter: eWizard2_0 www.oneabitech.com 10 Three distinct networks emerged over the course of the study, correlated with study pop. 11 Twitter: eWizard2_0 www.oneabitech.com Network evolved over three month time period, with some nodes leaving and coming AUG SEP OCT 12 Twitter: eWizard2_0 www.oneabitech.com Worse time to contract diseases starts early in the week – e.g. Today! Calendar Heatmap of contact events for entire study duration. 13 Twitter: eWizard2_0 www.oneabitech.com So if we perform a targeted removal of highly infectious individuals what happens? AUG Graph Density (.127 .098) Edges (198 130) Twitter: eWizard2_0 www.oneabitech.com SEP OCT 14 Public Health Official – “And so what?” Actionable data. Finding patient ZERO. When? Calendar Heatmap of contact events for select user. Who? Subject “_User$ri48ujTmJK” How? Where? 15 Twitter: eWizard2_0 www.oneabitech.com Where? Using geospatial information patient ZERO can be located, and path protected. 16 Twitter: eWizard2_0 www.oneabitech.com Where? Using geospatial information patient ZERO can be located, and path protected. _User$ri48ujTmJK Activity in_vehicle on_bike on_foot still tilting 64 unknown 34 4 49 580 96 17 Twitter: eWizard2_0 www.oneabitech.com Beyond Ebola, future emerging infectious diseases Continuous temperature tracking Household influenza tracking Disease forecasting NSF #1516340 [1] Abiola, S. O. Node: A Real Time Smartphone Big Data Application for Health Care Epidemiology. (2013). at http://dataspace.princeton.edu/jspui/handle/88435/dsp01sx61dm401 [2] Abiola, S. O., Portman, Eric., Kautz, Henry., Dorsey, E.R., Node View: A mHealth Real-time Infectious Disease Interface. Ubicomp/ISWC’15 Adjunct Proceedings. (2015). Twitter: eWizard2_0 www.oneabitech.com 18 Emerging infectious diseases platform – example case of Zika 19 Mobile Development and Analytics Courtesy of AbiTech, Inc. www.oneabitech.com Twitter: eWizard2_0 www.oneabitech.com 20