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Intercepting CKD in Primary Care Elizabeth Montgomery Sr. Project Director, NKF Primary Care Initiative National Kidney Foundation July 22, 2016 How can this be? Public Health Problem Engagement Issues • 22,000,000 at risk for adverse outcomes • Patients: asymptomatic so they can’t know until a medical professional tells them. • Unacceptably high rate of mortality • Extraordinary utilization of health care resources • Annual expenditures of a minimum of $100 billion for Medicare alone for 10% with diagnosis • Clinicians: they have the knowledge but do not apply it in practice • Insurers: It’s Medicare’s problem • Federal/State/Local Government: It’s not big enough/little to do One event has the greatest impact on improving health outcomes… Diagnosis Patient …when a patient seeks treatment Footer? X Clinician …and a clinician recognizes that the laboratory values presented represent an underlying condition that is treatable. Impact of Earlier Diagnosis on Health Outcomes Patient Life Cycle Symptom Onset Routine Screening: Routine BP check Lipid/cholesterol Mammogram/PAP Colonoscopy Search for Diagnosis Initial Diagnosis& Therapy Diagnosis Disorder Management Benefits: Increased longevity Fewer complications/side effects Improved quality of life Improved productivity Reduced health-related costs Patient Life Cycle Symptom Onset Search for Diagnosis Initial Diagnosis & Therapy Disorder Management 4 The “typical” CKD story Diagnosis Time in primary care Age-related kidney function decline Disease Management On average diagnosis received 6 months before dialysis starts Missed diagnostic opportunities Hypertension Diagnosis o o o o o o o o o o o o o o x x x x x x x x x x x x x x x x x x x x x x x x x x x x x xx Silent progressive decline in kidney function Type-2 Diabetes Diagnosis Symptoms CKD Onset ESRD - Dialysis Average life expectancy: 5 years 85 – 90% of CKD Patients Szczech, Lynda A, et al. "Primary Care Detection of Chronic Kidney Disease in Adults with Type-2 Diabetes: The ADD-CKD Study (Awareness, Detection and Drug Therapy in Type-2 Diabetes and Chronic Kidney Disease)." PLOS One - In press (2014). Tuot, Delphine S, et al. "Chronic Kidney Disease Awareness Among Individuals with Clinical Markers of Kidney Dysfunction." Clin J Am Soc Nephrol 6 (2011): 18381844. Diagnostic Delay: not exclusively a knowledge gap Clinician likelihood of identifying patient with CKD (n=445 PCPs) Clinician awareness: CKD screening in T2DM Clinician awareness: <60 eGFR indicates CKD Clinician awareness: >30 ACR in urine indicates CKD ≥50% <50% 0% 19 (4.3%) 217 (48.8%) 209 (47.0%) 100% 98.2% 97.6% 73.7% 59.9% 57.4% 57.9% 53.0% 54.5% Szczech LA, et al. PLoS One 9(11); 2014:e110535 Barriers to CKD Diagnosis • CKD is a largely asymptomatic presentation. • “CKD” is a relatively “new” nomenclature. • Many primary care clinicians were trained before the wide availability of the NKF guidelines, they may perceive that a CKD diagnosis has little utility as there is nothing that can be done to address CKD progression. • Lack of CKD diagnosis may not be understood by PCPs as a significant contributor to adverse events or a patient safety concern. • The absence of ongoing, timely feedback regarding the accuracy of CKD diagnosis may contribute to clinician overconfidence in CKD diagnosis. • Primary care clinicians (PCP) are trained (and compensated) to treat acute illness – there are challenges to implementing a chronic disease care model in primary care. …a major public health initiative leveraging demonstrated best practices in large scale change in health care. • • • • • Patient Journey Research Laboratory Interventions Improve engagement channels Tools to improve communication IMPROVED AWARENESS Consumers/ Patients • Performance Measures Pay for performance Population Health Interventions Disease Management/ Wellness Programs • • • • • • Diagnosis X Patient • • • Medical Societies/ Healthcare Providers Laboratory Profiling New approaches to CME Quality Improvement & Maintenance of Certification CME Research New tools Process changes (CPT Codes) Clinician • • • System Insurers Med School Training Residency curriculum Research Academia (Payers and Malpractice) • • • • • Medical Home Laboratory Innovations Novel approaches to testing • Industry (Laboratory, Diagnostic, & EMR) Government • • Pay for Performance Performance measures • • Hospitals & Health Networks Research Population Health Interventions • Improved communication Quality Improvement activities Developing performance measures Process changes (CPT codes) Population Health Model for CKD: – Establish preservation and protection of kidney health as a public health priority. – Ensure that assessment of kidney function is routine standard of care for at-risk populations in primary care. – Provide training and materials so that clinicians routinely engage their patients in conversations about the importance of kidney health and actively support patient alignment with behaviors that will protect it. – Provide people living with CKD the tools, information and resources necessary to make informed choices to protect their kidney health It’s all about perception… 10 CKD Prevalence, Diagnosis and Annual Cost 7 Increased utilization Increased hospitalization Increased mortality Cost per stage attributable to CKD: Honeycutt, A.A., et al., Medical costs of CKD in the Medicare population. Journal of the American Society of Nephrology : JASN, 2013. 24(9): p. 1478-83. CKD Diagnosis: Szczech, L.A., et al., Primary care detection of chronic kidney disease in adults with type-2 diabetes: the ADD-CKD Study (awareness, detection and drug therapy in type 2 diabetes and chronic kidney disease). PloS one, 2014. 9(11): p. e110535. 6 Prevalence CKD Diagnosis 5 Adult Population Percentage Prevalence and Medicare cost data: United States Renal Data System. 2015 USRDS annual data report: Epidemiology of Kidney Disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2015. 4 3 2 $3,000 1 $100+ billion annually $17,000 $0 $1,700 $80,000 0 Stage 1 Stage 2 Stage 3 Stage 4 Stage 5 Most people won’t solve a problem that they cannot see Kidney Disease Data Mining Illuminating the problem to engage and improve Case Study: Payer Group Over 3 million lives covered Before intervention: ~ 17,000 people with diagnosed CKD in database After intervention: 155,430 people with probable undiagnosed CKD identified Case Study: Primary Care Network • • Almost 140,000 lives covered After intervention: – 12,000 with probable undiagnosed CKD identified Case Study: Large Integrated Health Network • Almost 500,000 lives covered – 80% of patients with Stage 5 CKD not referred for nephrology – 65% of patients with Stage 4 CKD not referred to nephrology – 50% of patients with eGFR<60 on recommended medications CKDinsight Leadership summit to develop CKD Roadmap for change • Dr. Regina Benjamin 18th US Surgeon General Participants – CMS – HHS – IBM – Advocate Health – OhioHealth – Humana – Dialysis Clinic, Inc. – Walgreens – AAFP, AANP – Quest Laboratories – Anthem – HCSC – And others…. 13 Program Components 2016 Insight A leadership summit to clearly identify obstacles, define strategies to overcome them and build collaboration and momentum. Integrate Leveraging data mining and facilitated practice transformation to identify and manage CKD. Inform Innovative educational strategies for health professionals and people living with CKD. Thank you! Our Mission The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and wellbeing of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation. Our Vision To enhance the lives of everyone with, at risk of or affected by kidney disease. Key Fact The National Kidney Foundation is the leading organization in the U.S. dedicated to the awareness, prevention and treatment of kidney disease for hundreds of thousands of healthcare professionals, millions of patients and their families, and tens of millions of Americans at risk.