Download Medical Microbiology and Infectious Diseases

Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name: Denice Bay
Photo (optional):
Contact information including website address:
Rm 514C Basic Medical Sciences Bldg.
Department of Medical Microbiology and Infectious Diseases
University of Manitoba
745 Bannatyne Avenue
Winnipeg, MB, Canada R3E 0J9
Tel: (204) 977-5679
Fax: (204) 789-3926
Email: [email protected]
Website:
http://umanitoba.ca/faculties/health_sciences/medicine/units/medical_microbiology/faculty/denicebay
.html
Short Description of Research (3-4 sentences):
Examination of bacterial multidrug transporters and their lipid dependence to understand their
function, evolution, and structural biology using a multidisciplinary approach involving molecular
biology, microbiology, biochemistry, biophysics, and bioinformatics. Characterizing the antimicrobial
resistance of multidrug resistant efflux pumps transmitted via horizontal gene transfer between
Enterobacteriaceae. Developing screening arrays to identify antiseptic/disinfectant resistance
mechanisms among multidrug resistant bacteria.
Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name: Kevin Coombs
Photo (optional):
Contact information including website address: Manitoba Centre for Proteomics & Systems Biology
799 John Buhler Research Centre
204-789-3976
[email protected]
http://umanitoba.ca/faculties/health_sciences/medicine/
units/medical_microbiology/faculty/KevinCoombs.html
Short Description of Research (3-4 sentences):
Our lab is interested in understanding virus structure-function, assembly and pathogenesis, with
most recent focus on delineating how virus infection alters and is dependent upon the cellular
proteome. We study a variety of viruses, including reovirus, influenza and Zika virus. Our recent
proteomic screens identified several key cellular pathways such as apoptosis, autophagy and the
Ubiquitin-proteasomal system that these viruses require and we are currently elucidating exactly how
these cell signaling pathways affect the capacity of these viruses to replicate.
Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name:
Keith R. Fowke
Photo (optional):
Contact information including website address:
Keith R. Fowke, Ph.D.
Professor and Head,
Laboratory of Viral Immunology
Department of Medical Microbiology and Infectious Diseases
Max Rady College of Medicine
Rady Faculty of Health Sciences
539-745 Bannatyne Avenue
Winnipeg, Manitoba
Canada R3E 0J9
Telephone (204) 789-3818
Fax (204) 789-3926
http://umanitoba.ca/faculties/health_sciences/medicine/units/medical_microbiology/faculty/KeithFow
ke.html
Short Description of Research (3-4 sentences):
The Laboratory of Viral Immunology is a vital, active laboratory focused on training young scientists
through basic science studies in HIV infection. The lab studies why some people who are exposed
to HIV do not become infected and how we can use that information to prevent infection in
others. We also study how an over-activated immune response is a risk factor for acquiring HIV
or for rapid disease progression once infected. The lab is supported through funding by the
Canadian Institutes for Health Research and works in partnership with academic and
community groups in Nairobi, Kenya and Winnipeg, Manitoba.
Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name:
Dr. Ehsan Khafipour
Photo (optional):
Contact information including website address:
[email protected]
http://www.khafipourmicrobiomelaboratory.com
Short Description of Research (3-4 sentences):
The role of lifestyle factors, such as physical activity, nutrition, and sleep, in human health and disease is
well established. These lifestyle factors are often targeted by prevention and treatment strategies to
reduce chronic conditions, such as metabolic syndrome, diabetes, obesity and cardiovascular disease.
However, how these modifiable lifestyle factors interact with newer determinants of health, such as gut
microbiome and metabolic phenotype of the individual is relatively unknown. Both host genetics and
environmental exposures throughout the life (such as method of birth, breastfeeding, diet, and
medication use) can have life-long impact on gut microbiome. Gut microbiome on the other hand has
been shown to impact host physiology, metabolism, and immune function and to confer indirect
(immune-mediated) and direct resistance against enteric pathogens. Disruption of gut microbiome or
dysbiosis – which is referred to an abnormal balance of beneficial and protective members of microbiota
– has been linked to a growing number of chronic conditions such as obesity, insulin resistance and
inflammatory bowel diseases. The dysbiosis of gut microbiome impacts the profile of microbially-drived
metabolites and small molecules produced by the microbiota. These molecules influence the metabolic
and immunological capacities of the host both within and outside of the gut, i.e. through enterohepatic
pathway or gut-brain axis. Given the dynamics of the gut microbiome and metabolome, and their
potentially causal roles in multiple chronic diseases, microbiome and metabolome profiles of individuals
can be used as personalized biomarkers of health status, and thus, as targets for intervention.
During the phase I of this research program, we are conducting a cross-sectional investigation of the
interaction between lifestyle, genetics, and gut microbiota and how these are associated with additional
risk factors for chronic conditions prevalent in Manitobans, such as obesity, type 2 diabetes, metabolic
syndrome, and cardiovascular disease. Student will be involved in recruiting subjects and collection of
information and samples as well as DNA extraction, PCR amplification, bacterial sequencing and
bioinformatics analyses of data.
For more information about this project please visit: https://tmplr.ca/home
Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name: Kelly S MacDonald
Photo (optional):
Contact information including website address:
Head, Infectious Diseases
Sellers Research Chair
Professor of Internal Medicine & Medical Microbiology
University of Manitoba
Mail: 501-745 Bannatyne Ave, Winnipeg, MB, R3E 0J9
Email: [email protected]
Phone: 204-977-5680
Short Description of Research (3-4 sentences):
Dr. MacDonald research focuses on the development an effective HIV/SIV vaccine that induces a robust
cellular immune response in the genital mucosa, the natural site of infection. She has concentrated her
efforts on the use of Herpes family viruses, particularly Varicella Zoster Virus and Cytomegalovirus, as
viral vaccine vectors. Herpes viruses are well adapted to their hosts and are able to persist within the
host causing life-long infections. These adaptations are what make Herpes viruses an ideal vector for an
HIV/SIV cellular vaccine that can provide life-long protection.
Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name: Thomas Murooka
Photo (optional):
Contact information including website address:
Thomas Murooka
Assistant Professor
750 McDermot Ave, Room 433
Phone (204) 789 3941
Fax (204) 789 3921
Email: [email protected]
Website: www.murookalab.ca
Short Description of Research (3-4 sentences):
Our lab is interested in using advanced microscopy to visualize cellular motility during infection. The idea
is to study natural cellular functions in their most natural environment, and how infectious agents such
as bacteria and viruses, can alter these behaviors to block the immune system. By working in our lab,
students will be exposed to lab techniques in Molecular biology, Microbiology, Immunology and
Infectious Disease, and gain a deeper understanding of host-pathogen interactions.
Medical Microbiology and Infectious Diseases faculty interested in hosting an undergraduate student
applying for the Undergraduate Research Awards:
Name: Xiangguo Qiu
Photo (optional):
Contact information including website address:
Dr Xiangguo Qiu, National Microbiology Laboratory, Public Health Agency of Canada
Tel: (204) 784-7548 (O) (204) 789-5097 (Lab) E-mail: [email protected]
Web link:
http://umanitoba.ca/faculties/health_sciences/medicine/units/medical_microbiology/faculty/xiangguo
qiu.html
Short Description of Research (3-4 sentences):
I am actively doing research in the diagnosis, prevention, and treatment of high-risk pathogens such as
Ebola, Marburg, and Lassa viruses. With our modern high-containment lab and facilities, productive
works have been shown in my lab related to the development of vaccines and antiviral therapeutics. We
would like to have a student who has interest in immunology, virology, and molecular biology.
Medical Microbiology and
Infectious
Diseases
faculty
hosting an
undergraduate
student
applying
for
Undergraduate Research
Awards:
interested
the
in
Name:
Xiaojian
Photo
Yao
(optional):
Contact information
including
website
address:
XiaoJian Yao, Professor,
Director, Lab. of Mol. Human Retrovirology
Dept. of Medical Microbiology
University of Manitoba
204-977-5677
[email protected]
http://umanitoba.ca/faculties/health_sciences/medicine/units/medical_microbiology/faculty/xiaojian_y
ao.html
Short
Description
of
Research
(3-­‐4
sentences):
My lab is mainly working on the molecular biology of HIV, and the development of viral
vector based anti-cancer vaccine approach. There is two new projects on going: 1) the
biological role and impact of host CD40L on HIV replication; 2) Anticancer vaccine
development with viral vectors.
Medical Microbiology and Infectious Diseases faculty interested in hosting an
undergraduate student applying for the Undergraduate Research Awards:
Name: Dr. George G. Zhanel
Photo (optional):
Contact information including website address:
George G. Zhanel
Professor-Department of Medical Microbiology and infectious Diseases
Max Rady College of Medicine, Rady Faculty of Health Sciences, University of
Manitoba
Director-Canadian Antimicrobial Resistance Alliance (CARA, www.can-r.ca),
MS673 Microbiology, Health Sciences Center, 820 Sherbrook Street, Winnipeg,
CANADA R3A 1R9, Ph: 204 787-4902, Fax: 204 787-4699
Email: [email protected]
Short Description of Research (3-4 sentences):
The focus of the research is the study of infections caused by antimicrobial resistant
superbugs. The lab already consists of undergraduate students, graduate students,
medical students, technicians, clinicians and scientists. An excellent opportunity for a
gifted student to come and work and enjoy being around other successful individuals.